Quantifying the coating yield by modeling heat and mass transfer in a Wurster fluidized bed coater

Madlmeir, Stefan; Forgber, Thomas; Trogrlic, M.; Jajčević, Dalibor; Kape, A.; Contreras, L.; Carmody, Alan; Liu, P.; Davies, C.; Sarkar, Avik; Khinast, Johannes

doi:10.1016/j.ces.2022.117505

Cited by 20 publications

(7 citation statements)

References 62 publications

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“…Pietsch et al 353 revealed that the spouting at a stable regime has a more uniform coating quality in a prismatic spouted bed with liquid injection compared with an unstable regime, which is caused by the narrow distribution of particle circulation frequencies in stable condition. Madlmeir et al 354 showed that coating time could be reduced by up to 75% and the coating yield can be improved by up to 22% through selecting the appropriate inlet air flow rate (75 m 3 /h), inlet air temperature (34 °C), and spray rate (25 g/min) in the Wurster fluidized bed.…”

Section: The Biot Number (mentioning

confidence: 99%

Recent Advances in CFD Simulations of Multiphase Flow Processes with Phase Change

Zhu

Zhang

et al. 2023

Ind. Eng. Chem. Res.

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Phase change is a phenomenon that has been extensively utilized in chemical engineering, energy, electronics, vehicle, and space exploration. From both the science and engineering perspectives, gaining a profound understanding of the intricacies of multiphase flow processes accompanied by heat and mass transfer due to phase change is of fundamental importance. Indeed, the computational fluid dynamics (CFD) has been increasingly applied as an effective tool to give an in-depth and efficient analysis of the phase change processes, thereby enhancing our understanding and capacity to control and optimize the phase change effects in these processes. This paper seeks to provide a comprehensive review of the utilization of CFD methodologies in the simulations of phase change flows across various applications, including temperature management, drying, separation and purification, and others. First, the CFD models at various scales that are developed to elucidate the phase change processes are summarized. Second, the noteworthy advances in the recent CFD simulation work on various phase change processes are presented, respectively. Finally, the challenges and potential prospects to facilitate the application of the phase change flow are discussed. The current review aims to offer insightful guidance for the CFD modeling of phase change processes in numerous engineering application scenarios.

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Section: The Biot Number (mentioning

confidence: 99%

Recent Advances in CFD Simulations of Multiphase Flow Processes with Phase Change

Zhu

Zhang

et al. 2023

Ind. Eng. Chem. Res.

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“…Our previous research 29 made a residence time analysis for a Wurster coater based on this method and studied the effects of various geometric and operational parameters on the coating processes. Li et al, 30 Jiang et al, 31 Che et al, 4 Madlmeir et al, 32 Kalbag et al, 33 and Boehling et al 25 also performed similar residence time analysis for spray coating processes. This method is conceptually intuitive and can be easily implemented.…”

Section: Introductionmentioning

confidence: 98%

Evaluation of Coating Variability in a Wurster Coater via Ray Tracing and Spray Zone Methods

Song,

Zhou,

Bai

et al. 2024

Ind. Eng. Chem. Res.

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This study investigated systematically the coating processes of ellipsoidal tablets in a Wurster coater by coupling CFD-DEM simulations and postprocesses. The tablets were represented by superquadrics in the CFD-DEM simulations. Two postprocessing methods (i.e., the ray tracing method (RTM) and the spray zone method (SZM)) were established and compared. Their algorithms were introduced in detail, and the effects of important model and operation parameters were analyzed, including the number of rays, the number of facets per tablet, the time step of the postprocesses, the fluidizing gas velocity, and the spray angle. Implemented in a postprocessing mode, the two methods provided a flexibility to simulate different spray settings with only one round of DEM runs. The RTM is able to provide multiple pieces of information relating to the coating processes but with a relatively high computation cost. By contrast, the SZM is simpler and faster but cannot estimate the intratablet coating variability and the coating efficiency. Besides, it is generally difficult to define a spray zone accurately under various conditions for this method. There is no obviously better choice at this stage, and more comparisons with experiments should be implemented in the future.

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“…For example, in the production of inhalers, [ 1 ] careful control of droplet size is necessary to ensure effective delivery of medication to the lungs. Additionally, in spray drying, [ 2 ] smaller droplets can result in faster drying times, higher yields, and reduced production costs. In agriculture, optimizing spray coverage and penetration of pests [ 3 ] and weeds [ 4 ] may be achieved through controlling droplet size and distribution.…”

Section: Introductionmentioning

confidence: 99%

Free‐energy lattice Boltzmann simulations of slicing of rising droplets

Cao,

Liu,

Wang

et al. 2023

Can J Chem Eng

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We performed two‐dimensional simulations of the slicing of a rising droplet by a vertical knife and by two knives. We used a free‐energy lattice Boltzmann method. Most simulations are for an Eötvös number of 3.96 and a Morton number of 1.24 × . We carefully probed effects of the spatial resolution on the rising speed and slicing process. The effect of wettability of the knife(s) was studied by varying the equilibrium contact angle of the drop on the knife in the range of 45° to 135°. Slicing time as well as fine droplet fragments staying behind on the knife depend on the knife's wettability.

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Quantifying the coating yield by modeling heat and mass transfer in a Wurster fluidized bed coater

Cited by 20 publications

References 62 publications

Recent Advances in CFD Simulations of Multiphase Flow Processes with Phase Change

Recent Advances in CFD Simulations of Multiphase Flow Processes with Phase Change

Evaluation of Coating Variability in a Wurster Coater via Ray Tracing and Spray Zone Methods

Free‐energy lattice Boltzmann simulations of slicing of rising droplets

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