Quantifying mortality burden in patients with cancer due to <scp>COVID</scp>‐19 in the <scp>US</scp>: A national <scp>cross‐sectional</scp> analysis

Jambunathan, Bhaghyasree; Lang, Jacob; Mays, Malik; Ekwenna, Obi

doi:10.1002/cam4.6364

Cited by 1 publication

(1 citation statement)

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“…Mortality rates of cervical and uterine cancers were higher in black women than in those of other races during the study period. This goes in line with known findings which showed that age-adjusted mortality rates in patients with cancer and COVID‐19 were found to be significantly higher in NH Black or African American, Hispanic or Latino, and NH American Indian or Alaskan Native groups in 2020 [ 14 ].…”

Section: Discussionsupporting

confidence: 90%

Trends in gynaecologic cancer mortality and the impact of the COVID-19 pandemic in the United States

Xi,

Guo,

Qiu

et al. 2024

Infect Agents Cancer

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Objectives Our aim was to assess the trend in gynaecologic cancer (GC) mortality in the period from 2010 to 2022 in the United States, with focus on the impact of the pandemic on increased deaths. Methods GC mortality data were extracted from the Center for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research (CDC WONDER) platform. We analysed mortality trends and evaluated observed vs. predicted mortality for the period from 2020 to 2022 with joinpoint regression and prediction modelling analyses. Results A total of 334,382 deaths among adults aged 25 years and older with gynaecologic cancer were documented from 2010 to 2022. The overall age-standardised mortality rate (ASMR, per 100,000 persons) for ovarian cancer-related death decreased gradually from 7.189 in 2010 to 5.517 in 2019, yielding an APC (annual percentage change) of -2.8%. However, the decrease in ovarian cancer-related mortality slowed down by more than 4-fold during the pandemic. Cervical cancer -related mortality decreased slightly prior to the pandemic and increased during the pandemic with an APC of 0.6%, resulting in excess mortality of 4.92%, 9.73% and 2.03% in 2020, 2021 and 2022, respectively. For uterine corpus cancer, the ASMR increased from 1.905 in 2010 to 2.787 in 2019, and increased sharply to 3.079 in 2021 and 3.211 in 2022. The ASMR rose steadily between 2013 and 2022, yielding an APC of 6.9%. Conclusions Overall, we found that GC-related mortality increased during the COVID-19 pandemic, and this increase was not specific to age, race, or ethnicity.

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Section: Discussionsupporting

confidence: 90%