“…One possibility is to study the adhesion force (and the separation work) between a colloidal particle coated with fibronectin and a living cell (Hyonchol et al, ). Following a similar trend, silicon nitride tips can be functionalized with fibronectin to measure single molecule interactions with molecules adsorbed on surfaces, like for example glycans (Gelmi, Higgins, & Wallace, ). Another approach, closer to ours, would consist in using non‐specific interactions, for example between a silicon nitride tips and fibronectin coatings, to investigate adhesion, surface interactions, unfolding forces and the unfolding events (Donlon et al, ).…”