Quantification of Total Phenolics and Tannins in the Bark Extract and Evaluation of Antioxidant Activity of<i>Cinnamomum malabatrum</i>(Burm.F) Blume

Aravind, R; Sithunnisa, P.K.; Anjitha,; Alexeyena, V

doi:10.5958/0974-360x.2015.00013.x

Cited by 5 publications

(4 citation statements)

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“…All of the extracts had moderate amounts of phenolic compounds and showed potential activity against hydrogen peroxide, nitric oxide, and lipid peroxide free radicals [66]. A recent study investigated the antioxidant properties of several parts (i.e., the leaves, barks, and buds) of C. cassia .…”

Section: Antioxidant Activitymentioning

confidence: 99%

Cinnamon: A Multifaceted Medicinal Plant

Rao

Gan

2014

Evidence-Based Complementary and Alternative Medicine

557

332

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Cinnamon (Cinnamomum zeylanicum, and Cinnamon cassia), the eternal tree of tropical medicine, belongs to the Lauraceae family. Cinnamon is one of the most important spices used daily by people all over the world. Cinnamon primarily contains vital oils and other derivatives, such as cinnamaldehyde, cinnamic acid, and cinnamate. In addition to being an antioxidant, anti-inflammatory, antidiabetic, antimicrobial, anticancer, lipid-lowering, and cardiovascular-disease-lowering compound, cinnamon has also been reported to have activities against neurological disorders, such as Parkinson's and Alzheimer's diseases. This review illustrates the pharmacological prospective of cinnamon and its use in daily life.

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Section: Antioxidant Activitymentioning

confidence: 99%

Cinnamon: A Multifaceted Medicinal Plant

Rao

Gan

2014

Evidence-Based Complementary and Alternative Medicine

557

332

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“…On the other hand, the albumin concentration did not change markedly in rats treated with difenoconazole throughout the experimental period. Meanwhile, there was a signi cant elevation (by 40.19 and 54.60%) in the globulin level in rats treated with both doses of difenoconazole when compared with control group Table (4).…”

Section: Resultsmentioning

confidence: 96%

“…The total phenolic might be the main bio-active compounds which, a potent scavenger of hydrogen peroxide( H2O2),nitric oxide (NO)and lipid peroxide [Aravind et al .,2012].The antioxidant activities of phenolic compounds is due to their redox properties.…”

Section: Resultsmentioning

confidence: 99%

Phytochemical Screening of Cinnamon Cassia and Its Protective Effects Against Hepatotoxicity Induced By Difenoconazole in Male Albino Rats.

Mohamed¹,

El-Said²,

Arief³

2021

Preprint

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The objective of the present study has focused on the phytochemical analysis of Cinnamon cassia bark for determination of bioactive components, which have been associated with antioxidative stress induced by difenoconazole treatment in hepatic tissue of male albino rats. Ninety rats were assigned randomly to 9 groups, each group comprised of 10 animals. The first group served as control animals were administrated distilled water and the rest served as the experimental groups. Groups II and III animals were orally administrated with difenoconazole at doses of 58.9 and 117.8 mg/kg BW (represent of 1/20 and 1/10 of oral LD 50 , respectively) while the groups IV and V animals were received aqueous extract of cinnamon (AEC) at doses of 200 and 400 mg/kg BW , respectively . In addition groups VI and VII, animals were received AEC prior to 2h of administration with difenoconazole at low dose as well as groups VIII and IX, rats were received with AEC before treatments with high dose of difenoconazole for 28 days. Results of the present study indicated the presence of total phenolic, flavinoids and tannins as the main bioactive components in the AEC. Furthermore, the final body weight and liver index were increased markedly in difenoconazole-treated rats and these parameters values were comparable to control group following co-administration with AEC. However, difenoconazole-treatment induced a significant elevation in the level of (LPO) associated with adepletion of GSH level and an elevation in the activities of serum liver enzyme markers (i.e., AST ,ALT,ALP and GGT) was observed. These results confirmed with histopatlogical findings . In contrast, treatment with AEC in difenoconazole-treated rats elevated the level of endogenous hepatic antioxidant system (SOD, CAT and GSH) along with reducing the activities of serum liver enzymes. However, the hepatic protective property of AEC was further confirmed by histopathological findings. These findings may be attributed to the presence of total phenolic , flavoniods and tannins , which have anti-oxidative effect against oxidative injury- induced by tested fungicide.

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“…Phenolic compounds are found in almost all parts of the plants that responsive for anti-oxidant activity of cinnamon and a potent scavenger of hydrogen peroxide, nitric oxide, and lipid peroxide free radicals [46].…”

Section: Resultsmentioning

confidence: 99%

Cardioprotective effect of Cinnamomum zeylanicum extract on rats fed on high fat high fructose diet

Elmongy

Hussein²,

ahmed³

et al. 2022

BESPS

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Background: As a result of the increased consumption of sugar-rich and fatty-products, and the increase in the preference for such products, metabolic disorders are becoming more common at a younger age. Hyperlipidemia, insulin resistance [IR] and inflammatory status induced by high fat high fructose diet [HFHFD] increase the risk of developing cardiovascular diseases [CVDs] which are the leading cause of death worldwide. Objective: This study is aiming to determine the effects of HFHFD on cardiovascular disease [CVD]-related parameters. Also, the possible protective and curative effects of cinnamon extract on cardiac diseases. Methodology: Fifty adult male Sprague Dawley rats were divided into five groups: Group I: [control]. Group II rats were fed a diet with 45 kcal% fat and drink fructose 60% [HFHFD] for 8w. Group III: fed on HFHFD and pioglitazone [PGZ 20 mg/kg/b.wt]. Group IV: fed on HFHFD and cinnamon extract200mg/kg.b.w. Group V: fed on HFHFD and treated with combination of PGZ drug and cinnamon extract. At the end of the experiment, blood glucose, serum insulin, lipid profile, and oxidative stress markers were done. Heart tissues were used for Inflammatory cytokines [tumor necrosis factor-α [TNF-α] and interleukin 6 [IL-6], nuclear factor kappa [NF-κB], and cardiac enzymes beside histopathological examination. Results: HFHFD administration resulted signs of cardiomyopathy revealed by significant increase in blood glucose, serum insulin, homeostasis model assessment of IR [HOMA-IR] index with disturbed lipid profile. Also, significant increase in serum cardiac enzymes, inflammatory cytokines and oxidative stress markers were also noticed. PGZ and cinnamon extract treatment resulted in a significant decrease in glucose, insulin, and HOMA-IR index, amelioration of lipid profile, cardiac enzymes, inflammatory cytokines and oxidative stress markers. Conclusion: The current study revealed that cinnamon extract improves cardiomyopathy resulted from HFHFD administration possibly via hypolipidemic, anti-inflammatory and anti-oxidative ways. It can be used as food supplement has cardioprotective role in patients with metabolic disorders

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Quantification of Total Phenolics and Tannins in the Bark Extract and Evaluation of Antioxidant Activity ofCinnamomum malabatrum(Burm.F) Blume

Cited by 5 publications

References 0 publications

Cinnamon: A Multifaceted Medicinal Plant

Cinnamon: A Multifaceted Medicinal Plant

Phytochemical Screening of Cinnamon Cassia and Its Protective Effects Against Hepatotoxicity Induced By Difenoconazole in Male Albino Rats.

Cardioprotective effect of Cinnamomum zeylanicum extract on rats fed on high fat high fructose diet

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