Quantification of the impact of endometriosis symptoms on health-related quality of life and work productivity

Abstract

OBJECTIVE To quantify the impact of endometriosis-related symptoms on physical and mental health status, health-related quality of life (HRQoL), and work-related aspects (absenteeism, presenteeism, work productivity, activity impairment). DESIGN Cross-sectional quantitative study. SETTING Academic and research institution. PATIENT(S) Women (n=193) with self-reported surgically diagnosed endometriosis from the Endometriosis Patient Registry at Ponce School of Medicine and Health Sciences (PSMHS). INTERVENTION(S) Patients completed an anonymous questionnaire divided into three sections consisting of questions from the Patient Health Survey (SF-12®), the Endometriosis Health Profile (EHP-5), and the Work Productivity and Activity Impairment Survey (WPAI). MAIN OUTCOME MEASURE(S) Impact of endometriosis symptoms on physical and mental health status, health-related quality of life (HRQoL), absenteeism, presenteeism, work productivity and activity impairment was quantified. RESULTS Patients had SF-12 scores denoting significant disability in the phyisical and mental health components. They also reported an average of 7.41 hrs (approximately one working day) of work time loss during the week the symptoms are worse. In addition, WPAI scores show high impact on work-related domains: 13% of average loss in work time (absenteeism), 65% of their work was impaired (presenteeism), 64% loss in efficiency levels (work productivity loss), and 60% of daily activities perturbed (activity impairment). CONCLUSION Endometriosis symptoms such as chronic, incapacitating pelvic pain and infertility negatively and substantially impact the physical and mental health status, HRQoL, and productivity at work of patients with endometriosis.

Endometriosis Is Associated With a Shift in MU Opioid and NMDA Receptor Expression in the Brain Periaqueductal Gray

“…2,3 Unfortunately, endometriosis negatively impacts the daily life activities of women who suffer from it, often more so than other chronic conditions. [4][5][6] Other chronic conditions that produce pelvic pain have been shown to produce plastic changes in the brain, especially on structures functionally involved in pain and stress processing. [7][8][9] However, little is known about the central changes that may occur in endometriosis.…”

Abordagem Psicológica Na Endometriose: Experiência De Dor E Melhora Na Qualidade De Vida Das Mulheres

“…e) Vocational dimension -Fourquet, Báez, Figueroa, Iriarte and Flores (2011) found work productivity to be at high risk in women with the disease: 7.41 hours of work time per week are lost when symptoms are worse; they also concluded a high impact on work-related domains: 13% absenteeism, 65% of work impaired (presenteeism), 64% loss in work productivity, and 60% of activity impairment. Realizing the importance of a rehabilitative component, and the necessity to maintain an active professional life, work rehabilitation should be considered.…”

What Does Diagnosis of Endometriosis Mean? The Patient′s Perspective

“…Nearly one out of every two women with endometriosis has reported decreased work productivity because of the severity of symptoms from endometriosis [6]. Of these women whom have reduced work productivity, over one third of them attribute this reduction to loss in efficiency and impaired work activity [6].…”

“…Endometriosis is pathologically defined as the development of endometrial glands and stromal cells outside of the uterus, but this definition has broadened to include the development of any endometrial cell type (glands or stroma) outside of the uterus [3]. The development of endometriotic lesions induces a wide variety of symptoms with the most reported being that of chronic pelvic pain [4,5] and infertility [6]. Endometriotic lesions develop primarily in the pelvic region on the outer lining of abdominal organs, but have also been associated with pulmonary conditions [7].…”