2011
DOI: 10.1016/j.jchromb.2011.04.032
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Quantification of riboflavin in human urine using high performance liquid chromatography–tandem mass spectrometry

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Cited by 12 publications
(8 citation statements)
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“…It is well known that flavins degrade when exposed to light [39,40]. However, this happens only when flavins are present in free (unbound) state in solution [34,41].…”
Section: Effect Of Light-mentioning
confidence: 99%
“…It is well known that flavins degrade when exposed to light [39,40]. However, this happens only when flavins are present in free (unbound) state in solution [34,41].…”
Section: Effect Of Light-mentioning
confidence: 99%
“…RF is a light sensitive vitamin, so a pool of urine samples was placed in a clear glass bottle and exposed to white light of a lamp for 120 hours [8,10]. This sample was analyzed to confirm that the concentration of RF was not detected by the proposed method.…”
Section: Validation and Test Samplesmentioning
confidence: 99%
“…When RF intake is low, excretion is proportional to the intake [3]. The most widely used analytical methods for the quantification of RF in human urine samples are liquid chromatography (LC)-fluorescence detection (FD) [8], LC-tandem mass spectrometry (MS/MS) [9,10], fluorescence with flow-injection analysis [11], capillary electrophoresis (CE) [12,13], voltammetry [14] and chemiluminescence [15]. These methods require rigorous extraction steps, the use of significant amounts of organic solvents and long analysis time.…”
Section: Introductionmentioning
confidence: 99%
“…Hence, the sensitive and selective detection of riboflavin is of great importance. At present, various analytical methods [34][35][36][37] including high-performance liquid chromatography, surface plasmon resonance, mass spectrometry, fluorescence, and spectrophotometry, have been established for the detection of this analyte. However, most of the analytical techniques require complicated instrumentation, have relatively high cost, or suffer from poor sensitivity and low selectivity.…”
Section: Introductionmentioning
confidence: 99%