Quantification of regional calcium burden in chronic total occlusion by 64-slice multi-detector computed tomography and procedural outcomes of percutaneous coronary intervention

Atherosclerosis and extensive arterial calcification: The same condition?

“…In addition, percutaneous coronary intervention of calcified lesions results in significantly less late recoil and less optimal stent expansion than fibronecrotic or fibrocellular plaques [5]. Furthermore, patients with extensively calcified CA lesions hardly ever develop restenosis after stent implantation, thus suggesting burnt out soft tissue.…”

Predictors of Interventional Success of Antegrade PCI for CTO

“…Rolf et al (3) found that pre-procedural coronary CTA was associated with a higher PCI success rate than lack of preprocedural coronary CTA. Therefore, studies have focused on morphological characteristics observed on CCA and/or coronary CTA that could predict successful PCI, such as blunt stump, tortuous course, and calcification (6,11). Unfortunately, predictors of successful PCI on either coronary CTA or CCA were not consistent in those studies (6,11,15).…”

Three-Dimensional Quantitative Volumetry of Chronic Total Occlusion Plaque Using Coronary Multidetector Computed Tomography

“…8-14 Furthermore, recent developments in MDCT technology, including increased detectors and dedicated coronary artery analysis software, have enabled sophisticated volumetric plaque analysis on intravascular ultrasound (IVUS). 15, 16 We therefore reasoned that MDCT can provide additional information beyond coronary angiography, and can predict the success of CTO PCI. Background: The purpose of the present study was to investigate whether multidetector computed tomography (MDCT) can identify the nature of chronic total occlusion (CTO) plaque, which cannot be measured quantitatively using traditional coronary angiography, and predict the success of percutaneous coronary intervention (PCI).…”

“…8- 14 Furthermore, recent developments in MDCT technology, including increased detectors and dedicated coronary artery analysis software, have enabled sophisticated volumetric plaque analysis on intravascular ultrasound (IVUS). 15, 16 We therefore reasoned that MDCT can provide additional information beyond coronary angiography, and can predict the success of CTO PCI.…”