Quantification of oxytetracycline residues in samples of beef from the municipality of Arjona-Bolivar (Colombia)

Correa, Diofanor Acevedo; Castillo, Piedad Margarita Montero; Martelo, Raúl J.

doi:10.12988/ces.2018.84198

Cited by 2 publications

(1 citation statement)

References 11 publications

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“…For example in Colombia (Correa et al 2018a), all the 60 animal carcases evaluated had OTC residues and 6% of these exceeded the MRLs set by Colombian standards body. These high levels of OTC residues in the tissue samples could be due to exposure of the animals to antibiotics weeks or even days before slaughter, unauthorized use of the antimicrobials, over use of the drug, inadequate knowledge of the farmers and/or failure to apply instructions on the drug label (Agmas and Adugna 2018;Correa et al 2018a;2018b). The differences in the OTC levels recorded in our study and previous studies in Uganda and other countries could be due to differences in the sample sizes considered and the analytical techniques used for the detection and quantification of OTC residues.…”

Section: Discussionmentioning

confidence: 99%

Oxytetracycline residues in bovine muscles, liver and kidney tissues from selected slaughter facilities in South Western Uganda

et al. 2022

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Background Due to high disease burden and poor animal health services in Uganda, administration of antimicrobials particularly oxytetracycline (OTC) is often done by farm owners and workers without any prescription. This results in misuse of OTC with consequent high chances of antibiotic residues and antimicrobial resistance hence posing public health threat. The degree of public health threat from OTC use is not well established due to limited published data on antibiotic residues and usage in livestock production in Uganda. This study comparatively determined OTC residue levels in 318 samples of bovine muscles, liver and kidney tissues from Kiruhura, Mbarara and Ntungamo districts of South Western Uganda during dry and wet seasons. Results The results revealed that the overall OTC residues positivity levels was 74.84% while the district wise rates were 56.88%, 84% and 84.52% for Kiruhura, Mbarara and Ntungamo, respectively. The mean OTC residue levels in bovine muscles, liver and kidney tissues were above the recommended maximum residue limits of 200, 600 and 1200 µg/kg, respectively as established by FAO/WHO. Of the collected samples, 72.41% (236/318) had OTC residues in concentrations above the recommended maximum residue limits. Wilcoxon signed rank test results showed that change in the seasons did not cause any significant changes in the liver OTC residue levels for all the districts, though this was significant for muscles from Kiruhura and Mbarara districts. Unacceptably high OTC levels were found in the muscles, liver and some kidney samples: Kiruhura muscles and liver samples had mean OTC concentrations of 1094 ± 378 µg/kg and 967 ± 198 µg/kg; Mbarara muscles, liver and kidney samples had mean OTC mean concentrations of 668 ± 163 µg/kg, 3778 ± 1140 µg/kg and 12,576 ± 1630 µg/kg, respectively while Ntungamo samples had mean OTC concentrations of 586 ± 123 µg/kg and 5194 ± 1463 µg/kg in muscle and liver tissues. Conclusions The results of this study indicated that there are unacceptably high OTC residue levels in bovine tissues consumed in South Western Uganda. This poses a public and veterinary health threat to consumers of these bovine tissues.

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Section: Discussionmentioning

confidence: 99%

Oxytetracycline residues in bovine muscles, liver and kidney tissues from selected slaughter facilities in South Western Uganda

et al. 2022

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Presencia De Residuos De Doxiciclina en Carne Bovina Procedente Del Matadero Del Gobierno Autónomo Descentralizado Del Cantón Mejía, Ecuador

Michilena

Beltrán²,

Miño

et al. 2020

revista

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El objetivo de este estudio fue determinar la presencia de residuos de doxiciclina en carne de bovinos procedente del matadero del Gobierno Autónomo Descentralizado (GAD) del cantón Mejía, localizado en la provincia de Pichincha, Ecuador, durante el periodo comprendido entre el 29 de septiembre y el 26 de octubre de 2017. Durante el primer semestre de 2017 se faenaron mensualmente un promedio de 1.179 bovinos, estableciéndose el tamaño de la muestra en 160 muestras de músculo, las cuales fueron analizadas en el Laboratorio de Contaminantes de Productos Pecuarios de AGROCALIDAD mediante la técnica de Ensayo de Inmunoabsorción Ligando a Enzimas (ELISA). Se determinó que existe la presencia de residuos de doxiciclina en el 15,63% (25/160) de las muestras analizadas. La concentración promedio de residuos de doxiciclina fue de 16,6 µg/kg (1,5-95,0 µg/kg), donde el 80% (20/25) de las muestras positivas presentaron una concentración entre 1-25 µg/kg. Se corroboró el uso de doxiciclina en animales de producción que son destinados para el consumo humano, pero sin que los residuos de este antibiótico superen el Límite Máximo de Residuos (LMR) en músculo de bovinos establecidos a nivel internacional, siendo datos preliminares que se deben confirmar con el uso de otras técnicas de diagnóstico.

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Quantification of oxytetracycline residues in samples of beef from the municipality of Arjona-Bolivar (Colombia)

Cited by 2 publications

References 11 publications

Oxytetracycline residues in bovine muscles, liver and kidney tissues from selected slaughter facilities in South Western Uganda

Oxytetracycline residues in bovine muscles, liver and kidney tissues from selected slaughter facilities in South Western Uganda

Presencia De Residuos De Doxiciclina en Carne Bovina Procedente Del Matadero Del Gobierno Autónomo Descentralizado Del Cantón Mejía, Ecuador

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