Quantification of Lung Perfusion Blood Volume With Dual-Energy CT: Assessment of the Severity of Acute Pulmonary Thromboembolism

Abstract

Quantification of lung PBV with DECT is useful for assessment of the clinical severity of PTE and can be used as an indicator of right ventricular dysfunction.

Short-Term Subcutaneous Fondaparinux and Oral Edoxaban for Acute Venous Thromboembolism

“…20 This seems to support the limitations of lung PBV-based quantitative evaluation of mild PE used in the present study. The reasons for the absence of statistically significant differences between the pre-treatment and post-treatment lung PBV in the present PE patients are as follows.…”

Histogram-pattern analysis of the lung perfused blood volume for assessment of pulmonary thromboembolism

“…In addition, the method used to inject the contrast material and scan time of LPBV also affect the absolute and relative values of LPBV (10). Nevertheless, the morphologic information regarding the presence of PTE and functional information of lung perfusion impairment can be obtained in one examination using a dual-energy technique (9), and quantitative evaluations of PTE using LPBV indicate the degree of pulmonary perfusion when determined using a workstation (14). However, the variation of injection rate of contrast material or scan timing also affects the quantitative evaluation of DECT images.…”

Factors affecting the lung perfused blood volume in patients with intrapulmonary clots after anti-coagulation therapy

“…In this study, the initial and subsequent volumetric values of LPBV were evaluated based on the presence of IPCs, because the volumetric values of LPBV display correlations with factors suggesting the severity of PE [7,8], and, in particular, the relative values with a lower attenuation threshold ranging from 1 to 5 HU (%V 5 ) demonstrate a better correlation with these factors [7]. In the present study, the %V 5 values on subsequent LPBV images were significantly decreased compared with those on initial LPBV images in the patients with IPCs (Fig.…”

“…The results of quantitative http://dx.doi.org/10.1016/j.ejrad.2015.05.018 0720-048X/© 2015 Elsevier Ireland Ltd. All rights reserved. evaluations of the LPBV with a low attenuation range demonstrate a correlation with factors suggesting the severity of PE [7,8]. The LPBV values after treatment have also been reported to reflect the degree of pulmonary perfusion before and after treatment, including the compensatory increase in lung perfusion [9] however, there are no detailed analyses of factors affecting increased LPBV values after treatment.…”