Quantification of estrogens in infant formulas by isotope dilution liquid chromatography-tandem mass spectrometry

Abstract

Isotope dilution liquid chromatography-tandem mass spectrometry without any derivatization step was developed to screen estrogens in real infant formula samples.

Detection, Risk Assessment, and Survey of Four Polycyclic Aromatic Hydrocarbon Markers in Infant Formula Powder

“…Infant foods are wildly concerned for its potential safety issues [5,6]. It is reported that PAH levels are highest in fatenriched foods, including infant formula powder, that contain vegetable oils such as coconut oil, palm oil, and soybean oil [4,[7][8][9]; the oils have been reported to contain PAH contamination to varying degrees in the order of corn oil, grape seed oil, groundnut oil, olive oil, palm oil, pumpkin seed oil, rapeseed oil, rice bran oil, soybean oil, and sunflower seed oil [10][11][12][13]; the PAHs enter infant formula powders through these vegetable oils.…”

Development of a Matrix Certified Reference Material for Quantification of Aflatoxin B1 in Peanut Oils

“…In the case of the LC-IDMS/MS method, u A is the uncertainty originating from the repeatability of LC-IDMS/MS measurement, and u B is the uncertainty stemming from the pure AFB 1 CRM ( P std ), preparation of the calibration solution, and weighing of the sample ( m s , m IS ). However, as for the SA LC-FLD method, u A is the uncertainty originating from the repeatability of the SA LC-FLD measurement and u B is the uncertainty from the calibration curve, pure AFB 1 CRM ( P std ), and weighing of the sample ( m s ) . Additionally, the two methods have been regarded as equal precision.…”

“…However, as for the SA LC-FLD method, u A is the uncertainty originating from the repeatability of the SA LC-FLD measurement and u B is the uncertainty from the calibration curve, pure AFB 1 CRM (P std ), and weighing of the sample (m s ). 39 Additionally, the two methods have been regarded as equal precision. Thus, the standard uncertainty of value is characterized using the following equation (eq 14)…”