Quantification of caffeine and loperamide in printed formulations by infrared spectroscopy

Quantification of Inkjet-Printed Pharmaceuticals on Porous Substrates Using Raman Spectroscopy and Near-Infrared Spectroscopy

“…Edible icing sheets and solvent-casted films, containing cellulose derivatives, were used as the substrates (13). ATR-FTIR was used for quantifying loperamide and caffeine printed on poly-tetrafluoroethylene films (14). Recently, our group used Raman spectroscopy for the quantification of IJP haloperidol on inorganic compacts and commercial paracetamol tablets (15).…”

Orodispersible films: Towards drug delivery in special populations

“…Process monitoring and control in terms of content uniformity and compositional homogeneity in the printed dosage forms is one of the key issues to be addressed for IJ-ODF for quantification of two APIs in the printed dosage form (Palo et al, 2016). To this end, hyperspectral (Near Infrared, Raman, Terahertz spectroscopy, Raman spectroscopy and chemical imaging etc.)…”

Determination of theobromine and caffeine in some Malaysian beverages by liquid chromatography-time-offlight mass spectrometry

“…To the best of our knowledge, this study is the first to evaluate the contents of compounds in coffee and tea in Malaysia. The analysis of theobromine and caffeine in foods, biological fluids, environmental samples, plants, and water, was provided with different instrumental methods, such as highperformance liquid chromatography (HPLC) [4], gas chromatography-mass spectrometry-flame ionization detection (GC-MS-FID) [5], Fourier transform-infrared spectrophotometry (FT-IR) [6], near-infrared spectroscopy [7], UV-Vis spectrophotometry [8], FT-Raman spectrometry [9], and capillary electrophoresis (CE) [10]. Of these techniques, HPLC which offers advantages, such as simplicity and selectivity coupled with a UV-Vis detector, was deemed the preferred analysis system for the analysis of theobromine and caffeine [8,11,12].…”