Quantification of 9-Carboxy-11-nor-Δ9-tetrahydrocannabinol in Urine Using Brominated 9-Carboxy-11-nor-Δ9-tetrahydrocannabinol as the Internal Standard and High-Performance Liquid Chromatography with Electrochemical Detection

Simultaneous analysis of human plasma catecholamines by high-performance liquid chromatography with a reversed-phase triacontylsilyl silica column

“…Various antioxidant agents are used to protect the degradation of DHPG throughout analysis [9,19,25,26]. Extraction with cation-exchange columns [27], boronate gels [21,27], C18 matrix [12,13,16,[28][29][30], MFC18 [29] and PLRP-S or OASIS HLB [13,30] have provided good recoveries of NE and other catecholamines from plasma and urine. However, recoveries of other catecholamines and metabolites, such as DHPG and 3,4-dihydroxylalanine (DOPA) in plasma, have not been reported using this method.…”

“…These retention times, caused by intermolecular forces, change depending on the concentration of DPB and the particles. The recovery of NE was greatly improved when the concentration of DPB was decreased to 0.01%, compared with previously reports of 0.1 or 0.2% [12,16,29,30]. This improvement might be partly due to C30 particle characteristics.…”

“…Therefore, the measurement of both NE and DHPG plasma levels would offer accurate information about sympathetic activities, since these levels change under various physiological and pathological situations [2,5,[9][10][11]. Various catecholamine analytical methods using high performance liquid chromatography (HPLC) with electrochemical detection have been reported [12][13][14][15][16][17]. However, problems still exist with such analyses from potential interferences that may influence detection sensitivity.…”

Review: The Application of Liquid Chromatography Electrochemical Detection for the Determination of Drugs of Abuse

“…THC has also been determined in human urine using a novel brominated 9-carboxy-11-nor-∆ 9 -tetrahydrocannabinol as an internal standard [41]. Amperometric determination was undertaken at +0.85 V (vs. Ag/AgCl) using gradient elution.…”

Introducing absorptive stripping voltammetry: wide concentration range voltammetric phenol detection

“…Various sensing methods for phenolic compounds are used, including electrochemical techniques, [4][5][6] high performance liquid chromatography, 1,[7][8][9] which is sometimes used in conjunction with electrochemical techniques, 1,7,8 and spectrophotometry. 10,11 Given their high reliability and their speed of response signicant recent research has focussed primarily on electrochemical sensors.…”