Abstract:The IGRAs (Interferon-γ Release Assays) are commercial assays which measure T-cell-mediated response in vitro after specific stimulation, and represent the alternative to TST (Tuberculin Skin Test) in the diagnosis of latent tuberculosis infection (ILTB) and of active tuberculosis (TB). Among these we choose the assay QuantiFERON ® -TB Gold IT (Cellestis Ltd, Carnegie,Victoria, Australia) (QFT) in which interferon-γ (IFN-γ) was measured after lymphocyte stimulation with 3 antigens of the RD1 region of M. tuber… Show more
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