Quality of life with tuberculosis

Abstract

Tuberculosis diagnosis and treatment currently revolves around clinical features and microbiology. The disease however adversely affects patients’ psychological, economic, and social well-being as well, and therefore our focus also additionally needs to shift towards quality of life (QOL). The disease influences all QOL domains and substantially adds to patient morbidity, and these complex and multidimensional interactions pose challenges in accurately quantifying impairment in QOL. For this review, PubMed database was queried using keywords like quality of life, health status and tuberculosis, and additional publications identified by a bibliographic review of shortlisted articles. Both generic and specific QOL scales show a wide variety of derangements in scores, and results vary across countries and patient groups. In particular, diminished capacity to work, social stigmatization, and psychological issues worsen QOL in patients with tuberculosis. Although QOL has been consistently shown to improve during standard anti-tubercular therapy, many patients continue to show residual impairment. It is also not clear if specific situations like presence of comorbid illnesses, drug resistance, or co-infection with human immunodeficiency virus additionally worsen QOL in these patients. There is a definite need to incorporate QOL assessment as adjunct outcome measures in tuberculosis control programs. Governments and program managers need to step up socio-cultural reforms and health education, and provide additional incentives to patients, to counter impairment in QOL.

Prevalence and Risk Factors of Infection with High Risk Human Papilloma Viruses among HIV-Positive Women with Clinical Manifestations of Tuberculosis in a Middle-Income Country

“…This may have resulted in de novo HPV infections and re-infections. This scenario is supported by the latest evaluations of the positive effects of TB treatment on the physical, emotional and psychological health of TB patients [ 105 ]. Thus, sociodemographic features of WLWH with TB, suggested an explanation for the increased prevalence of HR HPVs in those receiving ART and ART/TB-treatments in their improved health allowing return to everyday life with capacity to work and upkeep sexual relations.…”

The Effect of Self-Care Education on the Quality of Life in Patients with Pulmonary Tuberculosis

“…The results also indicated that tuberculosis -from the most to the least-mostly affects the physical, functional/independence, and social/family domains of QoL. Prolonged cough, fever, weakness and fatigue, chest pain, and weight loss are among the most common physical problems caused by TB (2), which in turn reduce the patient's ability and physical function and pave the way for the emergence of social and family problems (30).…”

Model Tatalaksana Komprehensif Tuberculosis Multidrug-Resistant (TB-MDR) Melalui Pendekatan Provider Pelayanan Kesehatan

“…Saat ini layanan pengendalian TB terfokus terhadap penyembuhan terhadap mikrobiologisnya, sedangkan pasien TB juga mengalami penderitaan secara mental dan sosial. 13 Program kuratif sendiri dirasa memakan biaya cukup tinggi sehingga dilakukannya manajemen kesehatan dengan tatalaksana komprehensif diantaranya adalah promotif, preventif, kuratif, dan rehabilitatif dirasa lebih efektif. 14 Promosi kesehatan adalah kegiatan penyuluhan dengan tujuan memastikan perilaku dan kesejahteraan hidup manusia.…”