Quality of Life: Radical Prostatectomy Versus Radiation Therapy for Prostate Cancer

Lim, Arthur J.; Brandon, Alfred H.; Fiedler, Jeffrey A.; Brickman, Andrew L.; Boyer, Cynthia; Raub, William; Soloway, Mark S.

doi:10.1016/s0022-5347(01)66881-2

Cited by 200 publications

(109 citation statements)

References 21 publications

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“…17 This study did not assess generic domains of quality of life, but the researchers did report significant associations between symptoms and the physical domains of the Functional Living Index: Cancer, a cancer specific quality-of-life measure.…”

Section: Discussionmentioning

confidence: 94%

“…Prior studies that have reported results on the association between bowel symptoms and quality of life have not examined the impact across such a wide range of domains. 3,11,17 Using a single question (After your prostate carcinoma treatment, do you feel your overall quality of life is: better than before/same as before/worse than before? ), Kao and colleagues 3 found that incontinence and impotence were significant predictors of overall health status (OR, 0.41 and 0.34, respectively for better or same vs. worse).…”

Section: Discussionmentioning

confidence: 99%

“…The AUA Symptom Index ranges from 0 (no symptoms) to 35 (maximum symptoms). Lower urinary tract symptoms were categorized as none to mild (AUA scores from 0 through 7), low to moderate (8 -14), high to moderate (15)(16)(17)(18)(19), or severe (20 -35). High internal consistency (Cronbach ␣ ϭ 0.86) and test-retest reliability (r ϭ 0.92) have been reported for this scale.…”

Section: Assessment Of Sexual Urinary and Bowel Symptomsmentioning

confidence: 99%

“…However, very few studies have directly examined and compared the impact of these symptoms on overall and cancer specific quality of life. In one of the few studies that examined this issue, Lim and colleagues 17 found that problems with incontinence, sexual function, and bowel function were associated with depression, tension, and fatigue. More recently, two studies found that incontinence and impotence were associated with reduced overall quality of life for prostatectomy patients.…”

mentioning

confidence: 99%

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The association of treatment‐related symptoms with quality‐of‐life outcomes for localized prostate carcinoma patients

Bacon

Giovannucci

Testa³

et al. 2002

Cancer

142

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BACKGROUNDMost studies of treatment outcomes in men with localized prostate carcinoma have emphasized sexual, urinary, and bowel symptoms with the assumption that they have an impact on quality of life. However, very few studies have directly examined and compared the impact of these symptoms on overall and cancer specific quality of life.METHODSThe authors examined 783 incident cases of localized prostate carcinoma, diagnosed from 1993 to 1998, and 1928 age‐matched healthy controls from the Health Professionals Follow‐Up Study cohort. Information on frequency of ejaculation and urinary symptoms were collected before cancer diagnosis. After cancer diagnosis, the authors mailed a questionnaire including the Medical Outcomes Study Short Form–36 Health Status Survey (SF‐36), the Cancer Rehabilitation Evaluation System–Short Form (CARES‐SF), and the University of California at Los Angeles Prostate Cancer Index in 1998.RESULTSCases had slightly lower scores on most of the SF‐36 scales and reported much more bother from sexual, urinary, and bowel symptoms compared with healthy controls. Among prostate carcinoma patients, bowel symptoms had the greatest negative impact on quality of life, followed by sexual and urinary symptoms. As expected, treatment‐related symptoms were associated with the physical domains of quality of life, but psychosocial domains were just as strongly affected.CONCLUSIONSPatients and health care providers need to consider the potential mental quality‐of‐life impacts associated with prostate carcinoma treatment symptoms when making treatment decisions. Even after patients have completed cancer treatment, significant health impairments may remain. Health care providers should continue to address the mental and physical well‐being of prostate carcinoma patients in follow‐up care. Cancer 2002;94:862–71. © 2002 American Cancer Society.DOI 10.1002/cncr.10248

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Section: Discussionmentioning

confidence: 94%

Section: Discussionmentioning

confidence: 99%

Section: Assessment Of Sexual Urinary and Bowel Symptomsmentioning

confidence: 99%

mentioning

confidence: 99%

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The association of treatment‐related symptoms with quality‐of‐life outcomes for localized prostate carcinoma patients

Bacon

Giovannucci

Testa³

et al. 2002

Cancer

142

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“…Recently, there has been increasing recognition that cancer therapy significantly impacts on patients' quality of life (QOL). [4][5][6][7][8][9][10] For patients, survival rate is not the sole factor influencing choice of treatment. A treatment with a lower survival rate may be preferred if it conferred a life of superior quality.…”

Section: Introductionmentioning

confidence: 99%

Patient‐reported quality of life after radical prostatectomy for prostate cancer

et al. 1999

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Background: Increasingly, quality of life (QOL) assessments are receiving greater attention in the management of malignancies, including prostate cancer. We evaluated the impact of radical prostatectomy on patient QOL 12 months or longer after surgery. Patients and Methods:We evaluated the impact of radical prostatectomy on QOL in 60 patients with prostate cancer. The patients comprised two groups: the first group (n = 32) was evaluated 12 months or longer after radical prostatectomy; the second group (n = 28) was evaluated while awaiting radical prostatectomy. General health-related QOL was measured with the European Organization for Research and Treatment of Cancer Prostate Cancer QOL Questionnaire. Sexual function was assessed with the Sapporo Medical University Sexual Function Questionnaire. A newly developed instrument assessing urinary function was prepared only for the postoperative group. Results: No differences between the two groups were seen in comparisons of general health-related QOL subscales. Men who underwent surgery reported significant deterioration in sexual function (decreased quality of erection, decreased sexual activity and decreased satisfaction with sex life) than those awaiting surgery. Of the 32 postoperative patients, 26 (81%) did not use pads at all, five (16%) used one or fewer pads per day due to occasional spotting and only one patient (3%) used two to four pads per day to deal with urine dripping. Twenty-six postoperative patients (81%) stated that, given the choice, they would undergo radical prostatectomy again. Conclusions: General health-related QOL does not appear to be compromised following radical prostatectomy. Patients are willing to accept some morbidity for a perceived survival benefit. Although minimal urinary dysfunction was reported, most patients were dissatisfied with postoperative sexual function. In preoperative counselling, greater emphasis should be placed on the risk of postoperative impotence.

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Urinary and Sexual Function After Radical Prostatectomy for Clinically Localized Prostate Cancer

Stanford¹,

Feng²,

Hamilton³

et al. 2000

JAMA

1,057

576

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Quality of Life: Radical Prostatectomy Versus Radiation Therapy for Prostate Cancer

Abstract: Radical prostatectomy and external beam radiotherapy have comparable impact upon quality of life.

Cited by 200 publications

References 21 publications

The association of treatment‐related symptoms with quality‐of‐life outcomes for localized prostate carcinoma patients

The association of treatment‐related symptoms with quality‐of‐life outcomes for localized prostate carcinoma patients

Patient‐reported quality of life after radical prostatectomy for prostate cancer

Urinary and Sexual Function After Radical Prostatectomy for Clinically Localized Prostate Cancer

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