Quality of Life (Qol) Outcomes in Congenital Chronic Intestinal Pseudo-Obstruction

Schwankovsky, Lenore; DiLorenzo, Carlo; Cocjin, Jose; Mousa, Hayat; Rowhani, Anita; Hyman, P E

doi:10.1097/00005176-199810000-00060

Cited by 16 publications

(23 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In a parental proxy assessment, parents of children with intestinal pseudo-obstruction report lower QOL (specifically lower self-care and mobility, decreased school attendance and participation in social activities, worse mental health, lower self-esteem and more physical limitations) for their children compared with normal school children and children with juvenile rheumatoid arthritis (33). Although the results appear generally similar to the parental proxy assessments in our study and the tool was the same CHQ, the results of the pseudo-obstruction study were not reported in sufficient detail to make comparisons by domain.…”

Section: Discussionmentioning

confidence: 99%

Quality of Life after Pediatric Intestinal Transplantation: The Perception of Pediatric Recipients and Their Parents

Sudan¹,

Horslen

Botha

et al. 2004

American Journal of Transplantation

View full text Add to dashboard Cite

The objective was to examine the perception of physical and psychosocial functioning of pediatric intestinal transplant recipients who are beyond the perioperative period and compare these with normal and chronically ill children.Child and parent forms of the Child Health Questionnaire were administered to all 29 pediatric intestinal transplant recipients between the ages of 5 and 18 years who had had a small bowel transplantation 1 year previous and had a functional allograft. Comparison was made with published norms and scores for pediatric patients on hemodialysis.Intestinal transplant recipients (on average 5 years after intestinal transplantation and at a mean age 11 years) reported similar scores in all domains compared with normal children. Parents of intestinal transplant recipients noted decreased function in several domains related to their child's general health, physical functioning, and the impact of the illness on parental time, emotions and family activities.Intestinal transplant recipients beyond the perioperative period perceive their physical and psychosocial functioning as similar to normal school children. Parental proxy assessments differ from the recipients, with the parent's perception of decreased general health and physical functioning for intestinal transplant recipients compared with norms.

show abstract

Section: Discussionmentioning

confidence: 99%

Quality of Life after Pediatric Intestinal Transplantation: The Perception of Pediatric Recipients and Their Parents

Sudan¹,

Horslen

Botha

et al. 2004

American Journal of Transplantation

View full text Add to dashboard Cite

show abstract

“…Intestinal pseudo-obstruction remains a serious life-threatening disease with devastating effects for patients and their families, including significantly impaired quality of life 84 . The mortality is not clear but is thought to be in the order of 20-30% long-term 66,67 .…”

Section: Prognosismentioning

confidence: 99%

“…Increasing expertise in both the surgical and medical management has contributed to an improved prognosis especially to prevent complication such as sepsis and PN related liver disease. Outcomes from intestinal transplantation appear to be showing some improvement 83,84 . …”

mentioning

confidence: 99%

Gastrointestinal and nutritional problems in neurologically impaired children

Quitadamo

Thapar

Staiano

et al. 2016

European Journal of Paediatric Neurology

View full text Add to dashboard Cite

Fax: + 44 20 7813 8382Gut Motility disorders comprise a heterogeneous group of disorders that result from disruption of the functional integrity of the intrinsic neuromusculature of the gastrointestinal (GI) tract. This intrinsic neuromusculature includes the smooth muscle layers, the intrinsic nervous system of the GI tract (enteric nervous system or ENS) and the interstitial cells of Cajal. The contribution of each of these components to function can be compromised by alterations in structure (ranging from absence to derangement in numbers and/or anatomy) or of function (complete or partial failure in physiological function). This pathology can be primary or secondary to a number of insults e.g. infections, inflammation, toxins etc. In children disorders may be congenital being present from birth or acquired later in life. Finally involvement of the enteric neuromusculature can be patchy/segmental or affect the gastrointestinal tract diffusely.Neuro-gastroenterology is the study of the interface of all aspects of the gastrointestinal tract or digestive system with the different branches of the body's nervous system including the enteric, central and autonomic nervous systems. The combined terms 'Neurogastroenterology and motility' are designed to encompass the study of all the components of the enteric neuromuscualture and their modulating influences and represents one of the fastest growing areas in gastroenterology clinical practice and research. This chapter aims to address some of the most common neurogastroenterology and motility conditions seen in clinical practice ranging from those with defined pathology to those which fall under the umbrella of functional gastrointestinal disorders. The latter comprise some of the commonest but challenging disorders and the term 'functional' reflects the fact that in the majority of such conditions no organic cause can be found. It should also be noted that at the present time many functional disorders e.g. abdominal pain-related functional GI disorders, represent symptom complexes that can further be subdivided into more discrete entities e.g. irritable bowel syndrome, functional abdominal pain etc depending on the nature, location and associations of the symptoms. Clinicians will often rely on the presence or absence of 'red flags' e.g. associated weight loss, severe or significant symptoms etc to decide whether patients are likely to have organic or functional disorders. Exhaustive investigations in the latter are likely to prove fruitless, expensive and perpetuate 'illness behaviours' in the patients. Abdominal pain-related functional gastrointestinal disorders IntroductionAbdominal pain-related functional gastrointestinal disorders (FGID) constitute a spectrum of conditions characterised by the presence of recurrent abdominal pain in the absence of any defined pathology 1 . In the past these disorders fell under the single term 'Recurrent abdominal pain' (RAP) but have since been recategorised under an international initiative (Rome Foundation) to improve the dia...

show abstract

“…Although asymptomatic, rectosigmoidoscopy to obtain new biopsies was performed after four and five years of treatment. The mucosa was macroscopically normal and biopsies were only slightly positive for Red Congo (there were a few irregularly distributed amyloid deposits) (fig 1) and positive on immunohistochemistry for substance P. 2 To date, there has been no effective treatment for secondary amyloidosis [3][4][5] ; treatment consisted of treating the underlying inflammatory disease. 2 6 7 This case is interesting because, when treated with Infliximab, there was an important clinical and analytical improvement, apparently followed by a decrease in the degree of Red Congo stain for amyloid deposits.…”

Section: Secondary Amyloidosis In Crohn's Disease: Treatment With Tummentioning

confidence: 99%

“…In teenagers, chronic pain is related to low self care and decreased participation in school and social activities. 4 CB and TS both proved efficient for pain relief in cancer of the pancreas and in chronic pancreatitis. 5-7 CB with local anaesthetic agents appears quite safe but offers only transient relief.…”

mentioning

confidence: 99%

Bilateral thoracoscopic splanchnicectomy in chronic intestinal pseudo-obstruction: report of two paediatric cases

Khelif¹,

Scaillon²,

Govaerts³

et al. 2006

Gut

View full text Add to dashboard Cite

Quality of Life (Qol) Outcomes in Congenital Chronic Intestinal Pseudo-Obstruction

Cited by 16 publications

References 0 publications

Quality of Life after Pediatric Intestinal Transplantation: The Perception of Pediatric Recipients and Their Parents

Quality of Life after Pediatric Intestinal Transplantation: The Perception of Pediatric Recipients and Their Parents

Gastrointestinal and nutritional problems in neurologically impaired children

Bilateral thoracoscopic splanchnicectomy in chronic intestinal pseudo-obstruction: report of two paediatric cases

Contact Info

Product

Resources

About