Quality of Life of Women with Ovarian Cancer

Kornblith, Alice B.; Thaler, Howard T.; Wong, George Y.; Vlamis, Vaia; Mccarthylepore, Jean; Loseth, Diane B.; Hakes, Thomas; Hoskins, William J.; Portenoy, Russell K.

doi:10.1006/gyno.1995.0014

Cited by 147 publications

(109 citation statements)

References 4 publications

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“…As noted above, previous studies have found gynecologic cancer survivors to be at particularly high risk for emotional distress (Parker et al, 2003), with high rates of depressive symptoms (Kornblith et al, 1995). In a review of studies using DSM-IV criteria, Thompson and Shear (1998) reported that as many as 23% had major depressive disorder; our data were consistent, with 10% having symptoms suggestive of major depression and another 9% with subclinical symptomatology.…”

Section: Schemas Sexuality and Psychological Functioningsupporting

confidence: 85%

Sexual Self Schema as a Moderator of Sexual and Psychological Outcomes for Gynecologic Cancer Survivors

et al. 2008

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Gynecologic cancer patients are at high risk for emotional distress and sexual dysfunction. The present study tested sexual self schema as an individual difference variable that might be useful in identifying those at risk for unfavorable outcomes. First, we tested schema as a predictor of sexual outcomes,including bodychangestress. Second,we examined schema as a contributor to broader quality of life outcomes, specifically as a moderator of the relationship between sexual satisfaction and psychological statue (depressive symptoms and quality of life). A cross-sectional design was used. Gynecologic cancer survivors (N = 175) 2−10 years post treatment were assessed during routine follow up. In regression analyses controlling for sociodemographic variables, patients' physical symptoms/signs as evaluated by nurses, health status, and extent of partner sexual difficulties, sexual self schema accounted for significant variance in the prediction of current sexual behavior, responsiveness, and satisfaction. Moreover, schema moderated the relationship between sexual satisfaction and psychological outcomes, suggesting that a positive sexual self schema might "buffer" patients from depressive symptoms when their sexual satisfaction is low. Furthermore, the combination of a negative sexual self schema and low sexual satisfaction might heighten survivors' risk for psychological distress, including depressive symptomatology. These data support the consideration of sexual self schema as a predictor of sexual morbidity among gynecologic cancer survivors.

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Section: Schemas Sexuality and Psychological Functioningsupporting

confidence: 85%

Sexual Self Schema as a Moderator of Sexual and Psychological Outcomes for Gynecologic Cancer Survivors

et al. 2008

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“…Overall, 12 of the studies were rated as methodologically good, 5 were rated average, and 1 was rated poor. Levels of depression in ovarian cancer groups tended to be higher than in community samples, with percentages of those scoring above the clinical cut-off ranging from 21-25% in the good studies to 33% in the poor study [5] (though, interestingly, this study found that 23% of individuals experienced little or no distress). Notably, the prevalence of depression decreased after the 3-month period following completion of treatment [21], although it does not appear to differ across the first 6 weeks post-diagnosis [27].…”

Section: Resultscontrasting

confidence: 61%

“…Worse performance status was associated with increased levels of psychological distress in one good study [15] and one poor study [5], although one average study [21] found no relationship between Karnofsky performance status and levels of depression/anxiety. This suggests inconclusive evidence for a relationship between Karnofsky performance status and levels of psychological distress.…”

Section: Resultsmentioning

confidence: 91%

“…Being diagnosed with advanced stage disease was associated with increased levels of psychological distress in three good studies [3,16,25] and one poor study [5], although two average studies found no relationship between disease stage and levels of distress (Hipkins et al [21]; Stewart et al [28]ovarian cancer survivors). On the basis of these results, there is strong evidence that having advanced stage disease at diagnosis is associated with higher levels of psychological distress.…”

Section: Resultsmentioning

confidence: 99%

“…Not surprisingly, a number of studies have found elevated levels of anxiety and depression in patients with ovarian cancer [2][3][4]. However, one longitudinal study [5] found that 23% of ovarian cancer patients experienced little or no distress. Thus, the psychological sequelae of ovarian cancer are quite heterogeneous.…”

Section: Introductionmentioning

confidence: 99%

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Psychological distress and its correlates in ovarian cancer: a systematic review

2008

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Objective: Ovarian cancer is often diagnosed at an advanced stage, and consequently high levels of distress are often experienced. It is necessary to understand the factors associated with psychological distress in order to guide interventions to target those factors. The purpose of this systematic review was therefore to identify correlates of psychological distress in ovarian cancer.Methods: Included studies had to be quantitative and empirical, with standardized measures of psychological distress (anxiety or depression), and to present results for ovarian cancer patients specifically. Standard systematic search methods were used. Information about design, ovarian cancer sample size, disease stage, time since diagnosis, measures of distress used and findings was extracted from each study. The studies were quality assessed using experimenterdefined criteria as good, average and poor quality. Strength of the evidence (strong, some, inconclusive) was based on the quality and consistency of findings.Results: Eighteen studies meeting the inclusion criteria were identified. There was strong evidence for a relationship between younger age, being diagnosed with more advanced disease, more physical symptoms and shorter time since diagnosis with increased levels of anxiety and/ or depression. Additional factors (e.g. immune) tested in a few studies also emerged as correlates of distress.Conclusions: Demographic, disease and quality of life factors correlated with distress. However, too few studies assessed possible psychological and immunological correlates, which could be potentially modified and should be assessed in future studies.

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Symptom and quality of life survey of medical oncology patients at a Veterans Affairs medical center

Chang

Hwang

Feuerman³

et al. 2000

Cancer

301

222

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BACKGROUND The current study was conducted to assess symptom prevalence and symptom intensity and their relation to quality of life in medical oncology patients at a Veterans Affairs medical center. METHODS Consecutive inpatients and outpatients were asked to complete the Functional Assessment Cancer Therapy (FACT‐G), Memorial Symptom Assessment Scale (MSAS), and the Brief Pain Inventory. Symptoms then were analyzed by their relation to Karnofsky performance status (KPS) and quality of life. RESULTS Two hundred forty patients participated. The median number of symptoms was 8 per patient (range, 0–30 symptoms). The 5 most prevalent symptoms were lack of energy (62%), pain (59%), dry mouth (54%), shortness of breath (50%), and difficulty sleeping (45%). Patients with moderate intensity pain had a median number of 11 symptoms and patients with moderate intensity lack of energy had a median number of 13 symptoms. The number of intense symptoms increased as the KPS decreased (P < 0.001). Patients with moderately intense pain or fatigue also were more likely to experience nausea, dyspnea, and lack of appetite. The number of symptoms rated as present on the MSAS was found to correlate significantly with the FACT‐G Sum Quality of Life score. CONCLUSIONS Intense symptoms were highly prevalent in this population. The presence of pain, lack of energy, or poor performance status should lead to comprehensive symptom assessment. Patients free of disease nevertheless still may experience intense symptoms. The number of symptoms present may be a helpful guide to quality of life. Routine comprehensive symptom assessment may identify a significant fraction of patients who urgently require intensive symptom palliation. Cancer 2000;88:1175–83. © 2000 American Cancer Society.

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Quality of Life of Women with Ovarian Cancer

Cited by 147 publications

References 4 publications

Sexual Self Schema as a Moderator of Sexual and Psychological Outcomes for Gynecologic Cancer Survivors

Sexual Self Schema as a Moderator of Sexual and Psychological Outcomes for Gynecologic Cancer Survivors

Psychological distress and its correlates in ovarian cancer: a systematic review

Symptom and quality of life survey of medical oncology patients at a Veterans Affairs medical center

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