Quality of Life of Patients with Nephrolithiasis and Recurrent Painful Renal Colic

Abstract

Background: Quality of life (QoL) has not been a priority goal for patients with recurrent painful colic of renal lithiasis. Aim: To evaluate QoL in patients with recurrent painful symptoms due to renal colic. Methods: In this case-control study, 194 subjects (97 cases/97 controls) were matched according to age and gender. Cases were patients at an outpatient clinic with a confirmed diagnosis of nephrolithiasis with recurrent painful renal colic. The control group consisted of patients seen at an ophthalmology outpatient clinic for refraction symptoms. Main outcome measures: QoL was measured using the SF-36. Results: Average SF-36 dimension scores for cases and controls, respectively, were: physical function 70/95, role-emotional function 33.3/100, role limitations due to physical problems 25/100, bodily pain 41/84, general health status 52/82, vitality 45/80, social function 62.5/100 and mental health 52/84. All values were statistically different (p < 0.001). Using multiple linear regression, there was a statistically significant QoL drop in subjects with lithiasis. Low social and economic levels were associated with the following SF-36 domains: physical function, general health status, vitality and mental health. The influence of the diagnosis on role-physical and role-emotional domains. Analysis of the physical and mental components of the SF-36 Scale showed significantly lower averages between cases and controls: PCS (p < 0.001) and MCS (p < 0.001). Conclusion: The QoL of patients with painful recurrent symptoms due to renal colic was substantially impaired.

Study of quality of life and its determinants in patients after urinary stone fragmentation

“…Obesity and DM type 2 are quite prevalent in Saudi Arabia, which may explain their influence on patient HRQOL [24,25]. Another factor that had a negative impact on patient HRQOL is recurrent stones, likely due to the effects of recurrent symptoms due to renal colic, hence recurrent surgical procedures that could affect patient QOL [23,26]. …”

Use of drug therapy in the management of symptomatic ureteric stones in hospitalised adults: a multicentre, placebo-controlled, randomised controlled trial and cost-effectiveness analysis of a calcium channel blocker (nifedipine) and an alpha-blocker (tamsulosin) (the SUSPEND trial)

“…1 Repeated episodes have a detrimental influence on perception of quality of life. 2 Pain is usually felt in the abdomen but can go down into the groin and scrotum in males, and labia in females. Some people also get increased frequency and urgency of urination.…”

“…Overall, it does appear that these drugs demonstrate efficacy for passage of larger stones and for stones in the upper section of the ureter that are considered to be less likely to pass without active intervention. Primary outcome Rate of stone passage (20) Time to stone passage (2) n, number of trials using this option. Data extracted from Campschroer et al…”

Translation and Linguistic Validation of the Korean Version of the Wisconsin Stone Quality of Life Questionnaire

“…However, a questionnaire was developed to measure the inconvenience caused by ureteral stents earlier than urinary stone QoL [20]. About 10 years ago, papers about the QoL of patients with urinary stone began to be published [11,14,15]. Since then, the QoL for patients with urinary stone has been reported to be far worse and different than expected.…”

“…Although many studies have been published about the development of new treatment methods or the efficiency of treatment, few studies have focused on QoL of patients with urinary stone. The importance of QoL for patients with urinary stone has recently begun to be acknowledged and several studies have been published up to date [5][6][7][8][9][10][11][12][13][14][15][16][17]. With increasing interest in QoL of patients with urinary stone, research has also focused on how to evaluate QoL more accurately.…”