Quality of life of early stage colorectal cancer patients in Morocco

Abstract

Background: A multicentre cohort study was held in Morocco, designed to evaluate the quality of life of cancer patients. The aim of this paper is to report the assessment of the quality of life of early colorectal cancer patients, before and after cancer treatment, to identify other factors which are related to this quality of life. Methods: We used the third version of the QLQ-C30 questionnaire of the European organization for Research and treatment of Cancer (EORTC) after a transcultural validation. The Data collection was done at inclusion and then every twelve weeks to achieve one year of follow up. Results: Overall 294 patients presented with early colorectal cancer, the median age was 56 years (range: 21-88). The male-female sex ratio was 1.17. At inclusion, the global health status was the most affected functional dimension. For symptoms: financial difficulties and fatigue scores were the highest ones. Emotional and social functions were significantly worse in rectal cancer. Most symptoms were more present in rectal cancer. At inclusion, global health status score was significantly worse in stage III. Anorexia was significantly more important among colorectal female patients. For Patients over 70 years-old, the difference was statistically significant for the physical function item which was lower. Overall, Functional dimensions scores were improved after chemotherapy. The symptoms scores did not differ significantly for patients treated by radiotherapy, between inclusion and at one year. Conclusion: Our EORTC QLQ C30 scores are overall comparable to the reference values. Neither chemotherapy, nor radiotherapy worsened the quality of life at one year.

The impact of postoperative complications on health-related quality of life in older patients with rectal cancer; a prospective cohort study

“…Similar results were found in other studies with longitudinal QOL measurements [27][28][29] and confirmed by a systematic review of 23 studies regarding the changes in physical-and role functioning after colorectal cancer treatment [30]. Also, worse postoperative physical functioning in older patients compared to younger patients was described previously [7,[32][33][34][35][36][37]. Our results may add that older patients still report poor physical-, social-, and role functioning up to one year after diagnosis compared to their pretreatment level and compared to the reference population, indicating slow recovery or permanently affected functioning.…”

Health literacy and quality of life following rectal resections for cancer

“…This is in keeping with previous studies that found rectal cancer patients tend to report more symptoms than when compared to all comers of colorectal cancers. 23 Furthermore, it is also possible that this is a reflection of the timing of the quality of life assessment in our patient cohort. A significant proportion of patients were recruited and assessed during the early post-operative and/or during an acute non-elective hospital admission, where higher levels of symptoms are to be expected.…”

Hubungan Antara Optimisme Dengan Kualitas Hidup Pada Pasien Kanker

“…Artinnya, semakin rendah stadium pada pasien kanker maka semakin tinggi kualitas hidupnya. Hasil penelitian ini didukung oleh penelitian yang dilakukan oleh Mrabti et al (2016) menyatakan bahwa semakin rendah stadium atau stage kanker yang diderita oleh pasien kanker maka semakin baik kualitas hidupnya, hal ini ditunjukkan bahwa pasien dapat berfungsi lebih baik seperti fungsi fisik, peran, emosional, kognitif, dan sosial dibandingkan dengan pasien yang berada pada stadium yang tinggi.…”