Quality of life measures in health care. II: Design, analysis, and interpretation.

Fletcher, A. E.; Gore, S M; Jones, David R.; Fitzpatrick, Ray; Spiegelhalter, D. J.; Cox, D. R.

doi:10.1136/bmj.305.6862.1145

Cited by 293 publications

(181 citation statements)

References 13 publications

(1 reference statement)

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“…symptoms, signs, visual acuity or intraocular pressure) has been important in the study of medical and surgical interventions in eye disease. However, in the past decade, the evaluation of health and eye care has increasingly focused on health-related quality of life (HRQOL) as a critical outcome of treatment [1][2][3][4][5]. The reason is that functional measurements may not provide adequate characterization of the burden of disability in dayto-day activities from the patient's perspective.…”

Section: Introductionmentioning

confidence: 99%

Health-related quality of life following blind rehabilitation

Kuyk

Liu

Elliott³

et al. 2008

Qual Life Res

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Purpose-The purpose of this study was to investigate the effect of residential blind rehabilitation on patients' vision targeted health-related quality of life (HRQOL) and general physical and mental function.Methods-The National Eye Institute 25-item Visual Function Questionnaire (NEI VFQ) plus appendix questions, the 12 item Short-Form Health Survey (SF-12), Hope Scale and Coopersmith self-esteem inventory were administered to 206 legally blind veterans prior to their entering a residential (in-patient) blind rehabilitation program and again to 185 and 176 of the original cohort at two and six months after completion of the rehabilitation program, respectively. Data on visual acuity, visual field extent, contrast sensitivity and scanning ability were also collected. The duration of the in-patient rehabilitation programs ranged from 11-109 days. Questionnaire scores were compared pre-rehabilitation and post-rehabilitation.Results-Following rehabilitation there was a significant improvement in nine of eleven NEI VFQ subscales and in a composite score at both 2-and 6-month post-rehab intervals. Mental health (SF-12) and self esteem also improved significantly although physical health ratings declined over the course of the study (approximately 10 months).Conclusions-Residential blind rehabilitation appears to improve patients' self-reported visiontargeted HRQOL, self-esteem, and mental health aspects of generic HRQOL.

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Section: Introductionmentioning

confidence: 99%

Health-related quality of life following blind rehabilitation

Kuyk

Liu

Elliott³

et al. 2008

Qual Life Res

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“…Much effort has recently been put into the propagation of the idea of including QoL measures routinely in clinical QUALITY OF LIFE ASSESSMENT 5 research (e.g. Fitzpatrick et al, 1992;Slevin, 1992;Spieglehalter et al, 1992;Finlay & Dunlop, 1994), but still more efforts are needed in this direction. In our view, the field of QoL evaluation requires further intensive interdisciplinary collaboration of physicians, psychosocial researchers and biostatisticians.…”

Section: Cochioa and Ms Cmnmmentioning

confidence: 99%

Quality of life assessment in clinical cancer research

Olschewski¹,

Schulgen²,

Schumacher³

et al. 1994

Br J Cancer

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“…This is the difference between the drugs in the Journal of Human Hypertension change in a particular variable, divided by the pooled standard deviation at baseline. 12 …”

Section: Methodsmentioning

confidence: 99%

Bisoprolol and nifedipine retard in elderly hypertensive patients: effect on quality of life

et al. 2000

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Subjects over the age 60 with sustained sitting diastolic pressures of 95-115 mm Hg were randomised to a regime based on bisoprolol (n ‫؍‬ 368) or nifedipine retard (n ‫؍‬ 379) for 24 weeks. The goal diastolic pressure was р90 mm Hg and to achieve this, double-blind medication could be doubled (5/10 mg bisoprolol, 40/80 mg nifedipine retard) or hydrochlorothiazide 25 mg (unblinded) could be added to the higher dose. In an intention-to-treat analysis, 309 subjects in both the bisoprolol and nifedipine retard treated group provided at least a baseline and a second quality of life assessment (82%). An excess of symptoms was observed in the nifedipine group for oedema of the legs, nocturia, constipation, racing heart and heart thumping. Fewer patients reported wheeze in the nifedipine group. For

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Quality of life measures in health care. II: Design, analysis, and interpretation.

Cited by 293 publications

References 13 publications

Health-related quality of life following blind rehabilitation

Health-related quality of life following blind rehabilitation

Quality of life assessment in clinical cancer research

Bisoprolol and nifedipine retard in elderly hypertensive patients: effect on quality of life

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