Quality of Life Is Improved in Renal Transplant Recipients Versus That Shown in Patients With Chronic Kidney Disease With or Without Dialysis

Iqbal, MM; Rahman, Naimur; Alam, Morshed; Nath, Palash Kumar Deb; Waheed, Shahryar; Islam, Kamrul; Hossain, Rana Mokarram; Chowdhury, Ayub Ali

doi:10.6002/ect.tond-tdtd2019.p11

Cited by 19 publications

(20 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Several studies also reported better pain scores in the KTR group compared to the non-dialysis CKD 53 and haemodialysis groups. 53,54 However, it should be stressed that nearly half of KTRs still report some form of pain, a substantial prevalence that remains much higher than what is observed in the general population. We also observed prevalence of long-term pain, with nearly half of the CKD population suffering with chronic pain and 10% with neuropathic pain.…”

Section: J O U R N a L P R E -P R O O Fmentioning

confidence: 94%

The prevalence of pain among patients with chronic kidney disease using systematic review and meta-analysis

Lambourg

Guthrie

Murugan

et al. 2021

Kidney International

View full text Add to dashboard Cite

This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

show abstract

Section: J O U R N a L P R E -P R O O Fmentioning

confidence: 94%

The prevalence of pain among patients with chronic kidney disease using systematic review and meta-analysis

Lambourg

Guthrie

Murugan

et al. 2021

Kidney International

View full text Add to dashboard Cite

show abstract

“…Three studies compared HRQOL between KTRs and patients with CKD Stages 3–5 before RRT ( Table 3 ) [ 39 , 40 , 48 ]. Stomer et al [ 48 ] reported comparable physical and mental HRQOL for age-, gender- and estimated glomerular filtration rate (eGFR)-matched KTRs and CKD patients when measured by the SF-36.…”

Section: Resultsmentioning

confidence: 99%

“…Karine et al [ 39 ] reported marginally better physical and mental HRQOL in KTRs compared with patients with CKD Stages 3–5 after adjusting for age, sex, education and diabetes. Finally, Iqbal et al [ 40 ] described higher mean scores in all physical and mental HRQOL domains in KTRs (mean eGFR 49 mL/min/1.73 m 2 ) compared with patients with CKD Stages 3–5 (mean eGFR 36 mL/min/1.73 m 2 ).…”

Section: Resultsmentioning

confidence: 99%

Mapping health-related quality of life after kidney transplantation by group comparisons: a systematic review

Wang

Hemmelder

Bos

et al. 2021

Nephrology Dialysis Transplantation

View full text Add to dashboard Cite

Background Health-related quality of life (HRQOL) is becoming an increasingly important outcome in kidney transplantation. To describe HRQOL in kidney transplant recipients (KTRs), this systematic review summarizes literature that compared HRQOL between KTRs to other relevant populations (i.e. patients receiving dialysis, patients on the waiting list for kidney transplantation, patients with chronic kidney disease [CKD] not receiving renal replacement therapy (RRT), the general population, and healthy controls) and themselves before kidney transplantation. Methods The literature search was conducted in PubMed, EMBASE, Web of Science, and COCHRANE Library. Eligible studies published between January 2000 and October 2020 were included. Results 44 studies comprising 6929 KTRs were included in this systematic review. Despite the study heterogeneity, KTRs reported a higher HRQOL after kidney transplantation compared with pre-transplantation and compared with patients receiving dialysis with or without being on the waiting list, especially in disease-specific domains (i.e. burden and effects of kidney disease). Additionally, KTRs had similar to marginally higher HRQOL compared with patients with CKD stage 3-5 not receiving RRT. When compared with healthy controls or the general population, KTRs reported similar HRQOL in the first one or two years after kidney transplantation, and lower physical HRQOL and lower to comparable mental HRQOL in studies with longer post-transplant time. Conclusions The available evidence suggests that HRQOL improves after kidney transplantation and can be restored to but not always maintained at pre-CKD HRQOL levels. Future studies investigating intervention targets to improve or maintain post-transplant HRQOL are needed.

show abstract

“…They demonstrated that HD patients and hematological patients undergoing chemotherapy were more frequently severely fatigued compared with KTR, hematological patients in remission and healthy controls, but still had a lower overall QoL than healthy controls, comparable to hematological patients in remission [ 16 ]. In the study of Iqbal et al, the energy/fatigue score on the KDQOL-SF-36 scale were significantly better in KTR (66 ± 11) than in patients on chronic hemodialysis (40 ± 7) [ 24 ].…”

Section: Resultsmentioning

confidence: 99%

Fatigue in Kidney Transplantation: A Systematic Review and Meta-Analysis

et al. 2021

View full text Add to dashboard Cite

Fatigue is still present in up to 40–50% of kidney transplant recipients (KTR), the results of studies comparing the prevalence among patients on hemodialysis (HD) and KTR led to conflicting results. Fatigue correlates include inflammation, symptoms of depression, sleep disorders and obesity. Fatigue in KTR leads to significant functional impairment, it is common among KTR poorly adherent to immunosuppressive therapy and is associated with a serious deterioration of quality of life. The following databases were searched for relevant studies up to November 2020: Medline, PubMed, Web of Science and the Cochrane Library. Several studies have compared the prevalence and severity of fatigue between KTR and hemodialysis or healthy patients. They have shown that fatigue determines a significant functional deterioration with less chance of having a paid job and a significant change in quality of life. The aim of the review is to report methods to assess fatigue and its prevalence in KTR patients, compared to HD subjects and define the effects of fatigue on health status and daily life. There is no evidence of studies on the treatment of this symptom in KTR. Efforts to identify and treat fatigue should be a priority to improve the quality of life of KTR.

show abstract

Quality of Life Is Improved in Renal Transplant Recipients Versus That Shown in Patients With Chronic Kidney Disease With or Without Dialysis

Cited by 19 publications

References 1 publication

The prevalence of pain among patients with chronic kidney disease using systematic review and meta-analysis

The prevalence of pain among patients with chronic kidney disease using systematic review and meta-analysis

Mapping health-related quality of life after kidney transplantation by group comparisons: a systematic review

Fatigue in Kidney Transplantation: A Systematic Review and Meta-Analysis

Contact Info

Product

Resources

About