Quality of Life in Women with Endometriosis Pelvic Pain Treated with the Levonorgestrel-Releasing Intrauterine System

Abstract

Objective: To evaluate the quality of life in patients with endometriosis pelvic pain before and after the application of the levonorgestrel-releasing intrauterine system (LNG-IUS). Design: Open non-comparative study. Setting: Obstetrics and Gynecology Hospital at Monterrey, Mexico. Sample: 29 women aged 18 to 40 years with pelvic pain associated with endometriosis confirmed by laparoscopy. Methods: After laparoscopy but before LNG-IUS insertion (basal visit) and 6 months afterwards, modified Endometriosis Health Profile (EHP-30) was applied. Main outcomes measures: Size of change of questionnaire scores, need of additional analgesic therapy and adverse effects. Statistical Analysis: Differences in the questionnaire scores before and after intervention were analyzed by Student t-test. Results: Final analysis set included 29 women aged 31.7 ± 4.7 years years. The ASRM surgical staging of endometriosis was mild in 19.3 moderate in 13.7 and severe in 76% of the patients. The general perception of quality of life improved from 52 at baseline to 98% at six months (p < 0.001). Adverse events were mild in nature, 19 patients reported no adverse events during the study (65.5%). Two patients (6.9%) required the use of concomitant therapy with non-steroidal analgesics for relief of pain. Conclusion: The application of LNG-IUS in patients with pelvic pain associated with endometriosis improved significatively all aspects related with quality of life as measured with Endometriosis Health Profile (EHP-30). We concluded that LNG-IUS may be an effective and convenient therapeutic alternative for the management of pain associated with endometriosis. R. C. Flores et al.

Relação entre ocorrência de endometriose e sofrimento psiquíco

“…Outra consequência desse quadro patológico é o comprometimento da qualidade de vida das portadoras. Normalmente, a mulher, ao vivenciar essas mudanças e experimentar esses sentimentos, pode desenvolver quadros de depressão que, quando não são corretamente diagnosticados e tratados, interferem no tratamento da endometriose, agravando-a com o decorrer do tempo (8) :…”

Mulheres convivendo com endometriose: percepções sobre a doença

“…Hoje, esforços no ramo da medicina estão sendo feitos para que esse tempo reduza. Os achados de nossa pesquisa assemelham-se aos de outros estudos em que se constatou que a endometriose é quase que exclusividade da mulher no seu período reprodutivo 3,6 . A endometriose, por ser uma doença enigmática, seu diagnóstico é difícil e demanda considerável tempo, deste modo, as mulheres sofrem durante anos, na tentativa de descobrir o que se passa em seu corpo, o porquê de tantas dores e padecimento.…”

“…A taxa de prevalência de endometriose na população geral é desconhecida, porque o diagnóstico definitivo da condição é possível por cirurgia laparoscópica, portanto, muitos casos não são reconhecidos. No entanto, vários estudos relataram uma prevalência de 2-15% de endometriose entre as idades reprodutivas 6,7,8 . Além disso, estudos mostraram que 30 a 45% das mulheres com infertilidade ou dor sofrem de endometriose 8 .…”

Endometriosis Psychological Aspects: A Literature Review

“…Endometriosis is one of the most common gynecological chronic conditions, which affects women of childbearing age (1–5). Endometriosis is defined as abnormal positioning of endometrial tissue outside the uterus (2, 6). Endometriosis has a range of symptoms, from chronic pelvic pain to infertility (3, 6).…”

“…Endometriosis is defined as abnormal positioning of endometrial tissue outside the uterus (2, 6). Endometriosis has a range of symptoms, from chronic pelvic pain to infertility (3, 6). It also has a multi-factorial etiology, which is unknown in most cases (7, 8).…”