Quality of Life in Schizophrenia: A Meta-Analysis of Comparative Studies

Dong, Min; Lu, Li; Zhang, Ling; Zhang, Yun Shu; Ng, Chee H.; Ungvári, Gábor S.; Li, Gang; Meng, Xiangyi; Wang, Gang; Xiang, Yu Tao

doi:10.1007/s11126-019-09633-4

Cited by 66 publications

(64 citation statements)

References 58 publications

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“…Quality of life (QOL) refers to individuals' subjective perception of their own life status, which involves the domains of physical health, psychological state, social relations and living conditions (1). In the past decade, QOL has been paid more and more attention by psychiatrists because of its importance for outcomes of patients with mental illness (2)(3)(4), especially for schizophrenia (5,6), major depression (7,8) and bipolar disorder (9,10). In fact, QOL is not one of the traditional or formal measures of outcomes.…”

Section: Introductionmentioning

confidence: 99%

Quality of Life in Patients With Methamphetamine Use Disorder: Relationship to Impulsivity and Drug Use Characteristics

et al. 2020

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Background: The quality of life (QOL) of patients with methamphetamine use disorder (MAUD) is increasingly recognized as an important outcome. Previous studies have found that impulsivity is negatively associated with QOL in mental disorders, but this relationship is rarely confirmed in patients with MAUD. We hypothesized that impulsivity is negatively correlated with QOL in patients with MAUD based on previous findings. In addition, a variety of drug use characteristics of patients that may potentially affect their QOL need to be further explored. Therefore, the purpose of this study was to explore the relationship between impulsivity, multiple drug use characteristics, and QOL in patients with MAUD. Methods: A total of 379 patients with MAUD were recruited, and the majority of them were male (85.5%), with an average age of 33.93 ± 7.08 years. Two psychiatrists conducted semi-structured interviews with methamphetamine (MA) users in two compulsory drug rehabilitation centers to obtain their demographics and drug use characteristics. The Barratt Impulsiveness Scale-11 (BIS-11) and Brief WHO Quality of Life Assessment (WHOQOL-BREF) were used to assess patients' impulsivity and QOL, respectively. Correlation and univariate regression analysis were used to explore the relationships between impulsivity, a series of drug use characteristics and patients' QOL in different domains. Further multiple linear regression analysis was used to identify what extent the above clinical variables explained the variations in patients' QOL. Results: Age, marital status, employment, and various drug use characteristics were significantly associated with at least one QOL domain. Among them, married and full-time job were positively correlated with QOL, while others were negatively correlated with QOL. The total score of BIS-11 was significantly negatively correlated with all four domains of QOL. Impulsivity, a range of drug use characteristics and certain

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Section: Introductionmentioning

confidence: 99%

Quality of Life in Patients With Methamphetamine Use Disorder: Relationship to Impulsivity and Drug Use Characteristics

et al. 2020

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“…Quality of life is a major treatment goal for patients with psychiatric disorders [7,11,23]. A lowthreshold telemedical care programme consisting of regular telephone calls and SMS messages was able to improve quality of life compared to a control group in almost all aspects.…”

Section: Discussionmentioning

confidence: 99%

Telemedical care improves quality of life in patients with schizophrenia and bipolar disorder. Results of a randomized controlled trial

Stentzel

Berg

Strobel

et al. 2020

Preprint

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Background: Schizophrenia and bipolar disorder are serious psychiatric disorders with a high disease burden, many years lived with disability and a high level of risk of relapses and re-hospitalisations. Besides, both diseases are often accompanied with a reduced quality of life. A low quality of life is one predictor for relapses. This study examines whether a telemedical care programme can improve quality of life. Methods: “Post stationary telemedical care of patients with severe psychiatric disorders” (Tecla) is a prospective controlled randomised intervention trial to implement and evaluate a telemedical care concept for patients with schizophrenia and bipolar disorder. Participants were randomised in an intervention or a control group. The intervention group received telemedical care including regular, individualised telephone calls and SMS messages. The quality of life was measured with the German version of WHOQOL-BREF. Effects of telemedicine on quality of life after 6 months were analysed using t-tests to compare the intervention with the control group. Participants also evaluated the telemedical care program based on a short standardised interview.Results: 118 participants were recruited, thereof 57.6% men (n = 68). Participants were 43 years old on average (SD) 13)). The IG showed higher QoL scores than the control group (CG) 6 months after the baseline for the WHOQOL total sum score (t-test (CI) 93.1 (92.4-93.8) vs 89.7 (88.8-90.6), p < 0.0001) and for 4 of 5 domains: global 62.0 (60.9-63.0) vs. 56.8 (55.6-58.1), p < 0.0001; physical health 63.8 (63.0-64.7) vs. 59.6 (58.5-60.6), p < 0.0001; psychological 60.9 (60.0-61.9) vs. 56.4 (55.1-57.6), p < 0.0001; environment 70.8 (70.1-71.6) vs. 67.5 (66.7-68.3), p < 0.0001).Conclusion: The Tecla telemedical care concept has led to improvements in quality of life for patients with severe psychiatric disorders. It provides a low-threshold and suitable component of psychiatric treatment. Trial registration: German Clinical Trials Register, DRKS00008548, registered 21 May 2015 – retrospectively registered, https://www.drks.de/drks_web/setLocale_EN.do

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“…Quality of life is a major treatment goal for patients with psychiatric disorders [7,11,23]. A lowthreshold telemedical care program containing regular telephone calls and SMS-messages was able to improve quality of life compared to a control group in almost all aspects.…”

Section: Discussionmentioning

confidence: 99%

Telemedical care improves quality of life in patients with schizophrenia and bipolar disorder. Results of a randomized controlled trial

Stentzel

Berg

Strobel

et al. 2020

Preprint

View full text Add to dashboard Cite

Background Schizophrenia and bipolar disorder are serious psychiatric disorders with a high disease burden, a high number of years of life lived with disability and a high risk for relapses and re-hospitalizations. Besides, both diseases are often accompanied with a reduced quality of life. A low level of quality of life is one predictor for relapses. This study examines whether a telemedical care program can improve quality of life. Methods Post stationary t elem e di c a l c a re of patients with severe psychiatric disorders” (Tecla) is a prospective controlled randomized intervention trial to implement and evaluate a telemedical care concept for patients with schizophrenia and bipolar disorder. Participants were randomized to an intervention or a control group. The intervention group received telemedical care including regular, individualized telephone calls and SMS-messages. The quality of life was measured with the German version of the WHOQOL-BREF. Effects of telemedicine on quality of life after 6 months were analyzed using t-tests to compare the intervention with the control group. Participants also evaluated the telemedical care program based on a short standardized interview. Results 118 participants were recruited, thereof 57.6% men (n = 68). Participants were on average 43 years old (SD) 13). The IG showed higher QoL scores as the control group (CG) 6 months after baseline for the WHOQOL total sum score (t-test (CI) 93.1 (92.4-93.8) vs 89.7 (88.8-90.6), p < 0.0001) and for 4 of 5 domains: Global 62.0 (60.9-63.0) vs. 56.8 (55.6-58.1), p < 0.0001; Physical health 63.8 (63.0-64.7) vs. 59.6 (58.5-60.6), p < 0.0001; Psychological 60.9 (60.0-61.9) vs. 56.4 (55.1-57.6), p < 0.0001; Environment 70.8 (70.1-71.6) vs. 67.5 (66.7-68.3), p < 0.0001. Conclusion The Tecla telemedical care concept has improved the quality of life in patients with severe psychiatric disorders. It provides for a low-threshold and well suitable component in psychiatric treatment.

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Quality of Life in Schizophrenia: A Meta-Analysis of Comparative Studies

Cited by 66 publications

References 58 publications

Quality of Life in Patients With Methamphetamine Use Disorder: Relationship to Impulsivity and Drug Use Characteristics

Quality of Life in Patients With Methamphetamine Use Disorder: Relationship to Impulsivity and Drug Use Characteristics

Telemedical care improves quality of life in patients with schizophrenia and bipolar disorder. Results of a randomized controlled trial

Telemedical care improves quality of life in patients with schizophrenia and bipolar disorder. Results of a randomized controlled trial

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