Quality of Life in Sarcopenia and Frailty

Abstract

The reduced muscle mass and impaired muscle performance that defines sarcopenia in older individuals is associated with increased risk of physical limitation and a variety of chronic diseases. It may also contribute to clinical frailty.A gradual erosion of quality of life (QoL) has been evidenced in these individuals, although much of this research has been done using generic QoL instruments, particularly the SF-36, which may not be ideal in older populations with significant comorbidities. This review and report of an expert meeting, presents the current definitions of these geriatric syndromes (sarcopenia and frailty). It then briefly summarises QoL concepts and specificities in Europe PMC Funders Author ManuscriptsEurope PMC Funders Author Manuscripts older populations, examines the relevant domains of QoL and what is known concerning QoL decline with these conditions. It calls for a clearer definition of the construct of disability and argues that a disease-specific QoL instrument for sarcopenia/frailty would be an asset for future research and discusses whether there are available and validated components that could be used to this end and whether the psychometric properties of these instruments are sufficiently tested. It calls also for an approach using utility weighting to provide some cost estimates and suggests that a time trade off study could be appropriate.

Age-related decline in muscle mass and muscle function in Flemish Caucasians: a 10-year follow-up

“…This underlines the importance for public health-care systems to better understand age-related syndromes and diseases, such as sarcopenia. This condition is characterized by a progressive loss of skeletal muscle mass and its action generating capacity-also termed muscle function-and implies a risk of adverse outcomes such as fall-related injuries and impaired quality of life (Campbell et al 1989;Cruz-Jentoft et al 2010;Rizzoli et al 2013). In addition, it is estimated that the prevalence of sarcopenia is approximately 1-33 % in the community (both genders combined) and that this prevalence increases in older populations (Cruz-Jentoft et al 2014).…”

Muscle Mass and Quality of Life of Elderly People in Panti Tresna Werdha in Bandung

“…5 Komponen utama dalam mengukur kualitas hidup pada lansia adalah energi, bebas dari rasa sakit, mampu menjalani aktivitas hariannya. 6 Penurunan massa otot pada lansia akan mempengaruhi kapasitas fisiknya yang secara tidak langsung akan mempengaruhi kualitas hidupnya. 7 Peningkatan angka usia harapan hidup tidak selalu disertai dengan peningkatan kualitas hidup pada lansia.…”

Public Health issues in hospital management of Sarcopenic patients

“…The development of sarcopenia is considered to be the result of several factors including the genetic background 13 , age related hormones 14 , nutrition [14][15][16] , neurodegeneration 5,17 , chronic diseases 15,18 and disability, immobility and lack of physical activity 19 .…”

“…Sarcopenia is also associated with other diseases and predicts poor outcomes is some of them. Endocrine diseases, especially diabetes, kidney diseases 26,27 , coronary heart diseases are linked with sarcopenia and affect negatively the outcomes 18 . Sarcopenia, also, may interactively correlate with the presence and severity of age-related osteoarthritis 38 .…”