Quality of Life in Psoriasis

Colombo, Delia; Perego, Rita

doi:10.5772/53998

Cited by 7 publications

(8 citation statements)

References 107 publications

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“…Psoriasis has a negative impact on the psychological status, social interaction, and overall quality of life (QoL) of the patients [11,1]. Various studies showed that psoriasis affects day-to-day activities, occupational, and sexual functioning, often independent of the extent, and severity of skin lesions [12][13][14][15]. It was also demonstrated that it can cause anxiety, depression, anger, and embarrassment, which then leads to social isolation and absenteeism at work and school.…”

Section: Introductionmentioning

confidence: 99%

Management practice, and quality of life and its associated factors among ambulatory psoriatic patients attending Dermatological Center in Addis Ababa, Ethiopia

Kumsa

Tadesse

Woldu

2021

Preprint

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Background: Psoriasis is a chronic inflammatory disease characterized by keratinocyte hyperproliferation and aberrant differentiation with great negative impact on patients’ quality of life (QoL). This study aimed at assessing management practice, and quality of life (QoL) and its associated factors among ambulatory psoriatic patients visiting All Africa Leprosy, Tuberculosis and Rehabilitation Training (ALERT) Center in Addis Ababa, Ethiopia.Materials and methods: A cross sectional study was conducted among 207 patients with psoriasis attending the dermatology clinic of ALERT Center in Addis Ababa, Ethiopia. Data were collected using structured questionnaire and patients’ chart review. Dermatology Life Quality Index (DLQI) was used to measure patients’ QoL. Data was analyzed entered and analyzed using Statistical Package for Social Sciences (SPSS®) version 25. Descriptive statistics like frequency, percent, mean and standard deviation were used to summarize patients’ characteristics while binary logistic regression was utilized to identify predictors of quality of life. Results: Among 207 study participants, 122(58.9%) were females. The mean age of the study population was 37.92(SD=14.86) years (ranging from 16 to 68 years). The mean age at which diagnosis of psoriasis made was 32.0(SD=13.7) years ranging from 10 to 62 years. The duration of the disease in 112(54.1%) patients were more than or equal to 5 years. Among study participants, the majority of them, 145(70.0%) had plaque psoriasis followed by sebopsoriasis, 24(11.6%). The majority of plaque psoriasis (80%) cases were managed by topical corticosteroids with or without salicylic acid or coal tar and only 21(14.5%) treated by methotrexate alone. Other forms of psoriasis were treated by only topical corticosteroids with or without salicylic acid. The mean DLQI was 6.25 corresponding to a moderate effect. Symptoms and feelings were the most affected domains of QoL. Factors associated with poor QoL were female gender [AOR=0.17 (95%CI: 0.06, 0.48)], low, above average and high family income ([AOR=0.12(95% CI: 0.02, 0.56)], [AOR=0.06(95% CI:0.01, 0.32)], and [AOR=0.03 (95% CI: 0.01, 0.22)]) respectively and primary education level [AOR=0.14 (95% CI: 0.03, 0.64)] while being on systemic therapy [AOR=4.26 (CI: 1.18, 15.35)] was predictor of better QoL.Conclusion: Topical corticosteroids were the mainstay of psoriasis treatment in our study. The mean DLQI was 6.25, corresponding to a moderate effect on QoL. Study participants with female gender, primary education level, and low, above average, and high monthly family income were considered to have worse QoL whereas receiving systemic therapy significantly associated with better QoL. Hence, future interventions targeting improving QoL and widening treatment options for psoriasis deemed to be necessary.

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Section: Introductionmentioning

confidence: 99%

Management practice, and quality of life and its associated factors among ambulatory psoriatic patients attending Dermatological Center in Addis Ababa, Ethiopia

Kumsa

Tadesse

Woldu

2021

Preprint

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“…Psoriasis is a chronic disease with a significant impact on quality of life [ 4 ]. Most psoriasis cases can be managed in the primary healthcare setting [ 2 ]; however, the management of severe cases is a challenge even for experienced dermatologists [ 3 , 4 , 5 ]. For treatment, patients’ conditions can be grouped into mild, moderate, and severe forms.…”

Section: Introductionmentioning

confidence: 99%

“…For treatment, patients’ conditions can be grouped into mild, moderate, and severe forms. Mild cases can often be treated with topical corticosteroids and emollients that include vitamin D analogs, or retinoids, while cases with severe forms may need phototherapy or systemic therapy with retinoids, methotrexate, cyclosporine, apremilast, or biologic immune-modifying agents [ 2 , 3 , 4 , 5 ]. At this juncture, a holistic approach is valuable due to the biopsychosocial nature of the disease, and integrated healthcare could make a contribution to the treatment of psoriasis.…”

Section: Introductionmentioning

confidence: 99%

Investigation of the Relationship between the Disease Severity and Quality of Life of Psoriasis Patients and Their Anthropometric Measurements and Diets

et al. 2022

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Psoriasis is a multifaceted, chronic, inflammatory skin disease that impacts patients’ quality of life. The aim of this study was to investigate the relationship between the disease severity and quality of life of psoriasis patients and their nutritional status. The study included 40 patients in the psoriasis group, compared with 40 healthy individuals in the control group. A questionnaire for determination of socio-demographic characteristics and nutritional intake, anthropometric measurements, psoriasis area and severity index (PASI), and dermatology life quality index (DLQI) were used for the assessments. Daily food consumption details were recorded for three consecutive days to determine daily energy and nutrient intakes. Compared to the control group, the frequencies of single participants, primary school graduates, and housewives were higher in the psoriasis group (p < 0.05). The psoriasis patients weighed more and had an increased waist/hip ratio in comparison with the healthy individuals. The energy intake was lower in the psoriasis group (p < 0.01). There was not a significant statistical difference in the intake of proteins, fiber, vitamin A, vitamin E, vitamin C, Zn, Fe, and Mg supplements between the groups. However, there was an inverse correlation between the daily vitamin E intake and PASI scores (p < 0.05). There was a positive moderate correlation between the DLQI and PASI scores (p < 0.01). Our study indicated that lower daily vitamin E intake levels were associated with the severity of psoriasis. In addition to this, abdominal obesity seems to be another risk factor in psoriasis patients, even if they have a normal body mass index (BMI). An integrated healthcare approach with dermatologists, family physicians, and dietitians is essential to the management of psoriasis.

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“…This affects the patient´s psyche and may result in depression (5). Psychological problems associated with the disease affect a sufferer´s quality of life more substantially than the skin disease and its manifestations (6).…”

Section: Introductionmentioning

confidence: 99%

Psoriasis – the impact on an individual´s mental state and quality of life

Vévodová¹,

Havelka

Vévoda³

et al. 2019

J. appl. health sci. (Online)

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Introduction: Psoriasis is a chronic skin disease characterized by scaly patches affecting approximately 2-5% of the population. The disease has a negative impact on quality of life and, therefore, psoriatic patients often develop depression. Our work deals with quality of life and depression in psoriasis sufferrers and strives to determine the correlation between their quality of life and depression. Methods: The research took place in the University Hospital Olomouc in 2017 and used questionnaires WHOQOL-BREF and BDI-II. 50 patients with psoriasis were chosen randomly. To process the data we used Mann-Whitney test (the level of significance = 5%) and Spearman´s correlation coefficient (the level of significance = 1%). Results: The results proved that psoriasis has a significant impact on quality of life. The scores for the overall life quality as well as for individual domains were significantly lower in psoriatic patients than in the control group (p<0.001). The degree of depression in patients with psoriasis showed statistically significant correlation in all domains of the quality of life. We proved negative correlation in the overall quality of life (rs =- 0.691**), physical condition (rs =-0.499**), social relations (rs =-0.546**), overall health (rs =-0.396**), and environment (rs =-0.386**). Conclusion: With regard to the ascertained negative correlation between psoriasis and depression and lower quality of life of the sufferers compared to the healthy population, it is essential for healthcare professionals to pay attention not only to somatic manifestations of the disease but also to the patients´ mental health.

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Quality of Life in Psoriasis

Cited by 7 publications

References 107 publications

Management practice, and quality of life and its associated factors among ambulatory psoriatic patients attending Dermatological Center in Addis Ababa, Ethiopia

Management practice, and quality of life and its associated factors among ambulatory psoriatic patients attending Dermatological Center in Addis Ababa, Ethiopia

Investigation of the Relationship between the Disease Severity and Quality of Life of Psoriasis Patients and Their Anthropometric Measurements and Diets

Psoriasis – the impact on an individual´s mental state and quality of life

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