Quality of life in patients older than 75 years following major head and neck surgery

Khafif, Avi; Posen, Jennie; Yagil, Yaron; Beiser, Michael; Gil, Ziv; Ben‐Yosef, Rami; Landsberg, Roee; Fliss, Dan M.

doi:10.1002/hed.20635

Cited by 28 publications

(21 citation statements)

References 25 publications

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“…Khafif et al also found no differences in overall QOL between patients aged 75 or older when compared with younger counterparts. 16 However, they did suggest some subdomains of QOL were adversely affected by advanced age.…”

Section: Discussionmentioning

confidence: 99%

Quality of life after treatment of laryngeal carcinoma: a single centre cross-sectional study

Williamson

Ingrams

Jones

2011

annals

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The mainstays of treatment for head and neck cancers include surgery, chemotherapy and radiotherapy given alone or in combination. However, the side effects of these treatments are multifactorial in nature, causing substantial physical as well as psychosocial morbidity.1,2 Their location inherently affects life's basic and vital functions including breathing, feeding and oral communication. Furthermore, altered appearance, difficulty in swallowing and pain as a result of treatment can cause problems with social function and have a further effect on a patient's quality of life (QOL). 3A number of studies have revealed QOL is affected by T and N stage, 4,5 time after treatment and treatment modality. [5][6][7] Investigation into the effect of these factors on specific aspects of QOL such as saliva production and swallowing has yielded varying conclusions. 7-10The aim of this study was to identify whether factors including patient age, treatment modality, tumour stage and nodal status significantly affect quality of life in patients treated for laryngeal cancer. It was hypothesised that patients with advanced T stage and nodal disease would experience poorer QOL. Furthermore, patients undergoing surgical treatment with or without chemoradiotherapy would experience poorer QOL than those undergoing primary radiotherapy.We aimed to identify those aspects of QOL that are significantly affected in order to counsel patients regarding the significant risks and benefits of treatment with uncertain curative outcomes. Furthermore, we aimed to identify patients at risk of significant side effects before treatment in order to effectively prepare them for their treatment experience and focus support from health professionals on the appropriate patients. MethodsThe University of Washington Quality of Life (UW-QOL) questionnaire is a validated tool for determining QOL outcomes in patients treated for head and neck cancer.9,11,12 We used version 3 of the questionnaire (the most current at the time), which consists of ten domain specific questions that ask patients regarding their experiences of pain, appearance, activity level, recreation, swallowing, chewing, speech, shoulder function, taste and saliva production in the last seven days, compared to the month before they de- . We aimed to identify which aspects of QOL and which patients are most affected by the various treatment options. METHODS The University of Washington Quality of Life (UW-QOL) questionnaire was administered to all patients with laryngeal cancer treated at a single institution over a seven-year period (2003)(2004)(2005)(2006)(2007)(2008)(2009)(2010). RESULTS In total, 41 patients responded. All had been treated for squamous cell carcinoma of the larynx. Questionnaires were completed at a median of 18.5 months after treatment. The overall quality of life was 81.1/100 as assessed by the UW-QOL scale, with only 4.9% reporting 'poor' or worse QOL. Neither patient age nor time after treatment significantly affected any aspect of QOL. Patients undergoing primary r...

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Section: Discussionmentioning

confidence: 99%

Quality of life after treatment of laryngeal carcinoma: a single centre cross-sectional study

Williamson

Ingrams

Jones

2011

annals

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“…To improve on these limitations, future studies could benefit from being prospective and having documented reasoning for including or excluding a patient from surgery. Incorporating QOL measures would also be beneficial, which could be compared with current QOL data . Using the Hopkins Frailty Score tool to see its predictive value in microsurgical outcomes would be of interest …”

Section: Discussionmentioning

confidence: 99%

Surgical outcomes in the elderly patient after osteocutaneous free flap transfer

et al. 2014

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“…5 Although more aggressive treatment provides gains in terms of locoregional control and disease recurrence, 7 it can also have a negative impact on vital organ functions and quality of life. [8][9][10] Moreover, patients with head and neck cancer often suffer from other alcohol-and tobacco related diseases, such as cardiac and respiratory illnesses, second primary tumours, hepatic or metabolic diseases, as well as cognitive disorders, 3,5,11 that may decrease their resilience, quality of life and treatment tolerance. 4,[11][12][13][14][15] As a result, older patients and those with comorbidity are often given a modified treatment in an attempt to avoid treatment-related complications and mortality.…”

Section: Introductionmentioning

confidence: 99%

Age-related differences in guideline adherence for head and neck cancer

Hamaker

Smorenburg

Bun

et al. 2012

Journal of Geriatric Oncology

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Quality of life in patients older than 75 years following major head and neck surgery

Abstract: Several QOL domains are decreased in elderly patients undergoing major head and neck surgery.

Cited by 28 publications

References 25 publications

Quality of life after treatment of laryngeal carcinoma: a single centre cross-sectional study

Quality of life after treatment of laryngeal carcinoma: a single centre cross-sectional study

Surgical outcomes in the elderly patient after osteocutaneous free flap transfer

Age-related differences in guideline adherence for head and neck cancer

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