Quality of life in obstructive sleep apnea: a systematic review of the literature

Moyer, Cheryl A.; Sonnad, Seema S.; Garetz, Susan L.; Helman, Joseph I.; Chervin, Ronald D.

doi:10.1016/s1389-9457(01)00072-7

Cited by 219 publications

(178 citation statements)

References 33 publications

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“…The results of the present study are in contrast to some earlier studies in similar settings in which the benefit of nCPAP was clear; 11,17,29,32 however, opposite results have also been reported. For example, in a wellplanned randomized study by Profant et al, 33 patients in both the control group and the nCPAP group showed only minor improvement in quality of life.…”

Section: Discussioncontrasting

confidence: 99%

“…Although earlier controlled studies have shown that nCPAP treatment is efficacious in selected sleep apnoea patients, 11,17,29 the true effectiveness of this treatment under everyday conditions has so far remained largely unproven. The strength of the present study is that it provides data on the effectiveness and costs of normal routine hospital practice, when patients are treated under currently accepted indication criteria and guidelines within the ordinary routine of a large university hospital.…”

Section: Discussionmentioning

confidence: 99%

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Effect of Nasal Continuous Positive Airway Pressure Therapy on Health-related Quality of Life in Sleep Apnoea Patients Treated in the Routine Clinical Setting of a University Hospital

et al. 2008

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The effectiveness and cost-utility of nasal continuous positive airway pressure (nCPAP) treatment was evaluated in obstructive sleep apnoea syndrome (OSAS), using a 15D health-related quality of life (HRQoL) instrument in a routine clinical setting. In total, 78 OSAS patients (43 receiving nCPAP; 35 receiving lifestyle guidance) were included in the study. nCPAP treatment had a minor effect on the total HRQoL score; only the dimension of sleep improved in both groups. The mean ± SD number of quality-adjusted life years (QALYs) gained was 0.016 ± 2.34 in the nCPAP group and 0.386 ± 1.16 in the lifestyle guidance group. The mean cost per QALY gained was ¤73 375 for the nCPAP group and ¤845 for the lifestyle guidance group. The effect of nCPAP treatment on the HRQoL in a population of unselected OSAS patients was surprisingly small and the cost per QALY gained was high.

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Section: Discussioncontrasting

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Effect of Nasal Continuous Positive Airway Pressure Therapy on Health-related Quality of Life in Sleep Apnoea Patients Treated in the Routine Clinical Setting of a University Hospital

et al. 2008

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“…In our exercise, we did not explore the impact of screening on intangible outcomes, such as drivers' quality of life (47)(48)(49). Quality of life may improve with treating cases that are identified by screening (49,50), provided that patients adhere to therapy.…”

Section: Discussionmentioning

confidence: 99%

Estimated cost of crashes in commercial drivers supports screening and treatment of obstructive sleep apnea

Gurubhagavatula

Nkwuo

Maislin

et al. 2008

Accident Analysis & Prevention

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Sleep apnea among commercial drivers may increase the risk of fall-asleep crashes, which incur large expenses. Drivers of passenger cars whose apnea is treated experience lower crash risk. Among community-based holders of commercial driver's licenses, we considered three methods for identifying sleep apnea syndrome: 1) in-lab polysomnography; 2) selective in-lab polysomnography for high-risk drivers, where high risk is first identified by body mass index, age and gender, followed by oximetry in a subset of drivers; and 3) not screening. The costs for each of these three programs equaled the sum of the costs of testing, treatment of identified cases, and crashes. Assuming that treatment prevents apnea-related crashes, polysomnography is not costeffective, because it was more expensive than the cost of crashes when no screening is done. Screening with BMI, age and gender, however, with confirmatory in-lab polysomnography only on high-risk drivers was cost-effective, as long as a high proportion (73.8%) of screened drivers accepts treatment. These findings indicate that strategies that reduce reliance on in-laboratory polysomnography may be more cost-effective than not screening, and that treatment acceptance may need to be a condition of employment for affected drivers.

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“…-a major interference with the quality of life as measured objectively on specific questionnaires 21,27,29,67,71,85 .…”

Section: -Introductionmentioning

confidence: 99%

“…The narrowness of air passages can be discerned by means of cephalometrics 9,71 , acoustic rhino-manometrics 69 , endoscopy 47 , and magnetic resonance imaging 7,22,28 .…”

mentioning

confidence: 99%

How to detect Obstructive Sleep Apnea Syndrome (OSAS) in children

Seailles¹,

Couloigner²,

Cohen-Lévy³

2009

J Dentofacial Anom Orthod

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Obstructive Sleep Apnea Syndrome (OSAS) is a frequently occurring childhood malady, whose is incidence is largely underestimated, that can lead to serious complications. Because of their understanding of the anatomy and physiology of the masticatory apparatus and of the upper airways, orthodontist are in a strategic position to detect in their young patients developing disorders in these regions; accordingly when they suspect the existence of OSAS they should ask systematic and well targeted questions of parents who may not be aware of the relationship between certain symptoms their children display and sleep breathing problems. The goal of this article is to provide practitioners with a better understanding of the symptoms and the physio-pathological mechanics of OSAS so that they can spare their afflicted patients the complications it provokes by seeing that early treatment is undertaken. KEYWORDSObstructive sleep apnea syndrome Children Diagnosis Polysomnography.

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Quality of life in obstructive sleep apnea: a systematic review of the literature

Cited by 219 publications

References 33 publications

Effect of Nasal Continuous Positive Airway Pressure Therapy on Health-related Quality of Life in Sleep Apnoea Patients Treated in the Routine Clinical Setting of a University Hospital

Effect of Nasal Continuous Positive Airway Pressure Therapy on Health-related Quality of Life in Sleep Apnoea Patients Treated in the Routine Clinical Setting of a University Hospital

Estimated cost of crashes in commercial drivers supports screening and treatment of obstructive sleep apnea

How to detect Obstructive Sleep Apnea Syndrome (OSAS) in children

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