Quality of Life in Keratoconus Patients After Penetrating Keratoplasty

Yıldız, Elvin; Cohen, Elisabeth J.; Virdi, Ajoy S.; Hammersmith, K.M.; Laibson, Peter R.; Rapuano, Christopher J.

doi:10.1016/j.ajo.2009.10.005

Cited by 43 publications

(42 citation statements)

References 15 publications

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“…10 The domain scores were similar to or lower than those reported in studies assessing patients with other chronic diseases, such as keratoconus patients after penetrating keratoplasty, with the exceptions of short distance vision activities, long distance vision activities, vision-related social functioning, driving, and color vision. 25 In this study, no statistically significant differences were observed in the color vision and peripheral vision domains of the NEI-VFQ between dry eye and control groups. This was expected, as dry eye has little impact on the fundus, which is involved in both color vision and peripheral vision.…”

Section: Discussionmentioning

confidence: 71%

“…7,25 This evaluation is important for obtaining a more complete understanding of the effects of treatments and the natural history of disease on an individual's daily routine. Miljanovic et al 6 evaluated the impact of dry eye on visionrelated QoL in the Women's Health Study and Physicians' Health Study by sending a supplementary questionnaire asking how much everyday activities were limited by symptoms of dry eye, and to what degree eye problems limited reading, driving, working at the computer, professional activity, and watching television.…”

Section: Discussionmentioning

confidence: 99%

“…Eleven of the 12 scale scores (excluding the general health item) were averaged to yield a composite score. 12 The Chinese version of NEI-VFQ used in this study has been assessed for reliability and validity and it has been shown to accurately measure vision-related QoL in Chinese individuals. [13][14][15] The OSDI, developed by Allergan, Inc., is a 12-item, patient reported outcome.…”

Section: Survey Instrumentmentioning

confidence: 99%

See 2 more Smart Citations

Assessment of Vision-Related Quality of Life in Dry Eye Patients

Gong

Chapin

et al. 2012

Invest. Ophthalmol. Vis. Sci.

164

136

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Section: Discussionmentioning

confidence: 71%

Section: Discussionmentioning

confidence: 99%

Section: Survey Instrumentmentioning

confidence: 99%

See 1 more Smart Citation

Assessment of Vision-Related Quality of Life in Dry Eye Patients

Gong

Chapin

et al. 2012

Invest. Ophthalmol. Vis. Sci.

164

136

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“…Participants were divided into three groups based on the average of the steep keratometry (K) readings: mild (average Sim K < 45 diopters [D]), moderate (average Sim K 45-52 D), and severe (average Sim K > 52 D). 5,31 Ethical approval was obtained, and all patients who agreed to participate signed a consent form. The study was conducted in accordance with the tenets of the Declaration of Helsinki.…”

Section: Methods Participantsmentioning

confidence: 99%

Assessment of the Impact of Keratoconus on Vision-Related Quality of Life

Gothwal

Reddy

Fathima

et al. 2013

Invest. Ophthalmol. Vis. Sci.

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PURPOSE. We determined if the Impact of Vision Impairment (IVI) is a valid questionnaire to measure the vision-related quality of life (VRQoL) in keratoconus patients, and investigated if the VRQoL varied with disease severity in this sample. METHODS.We recruited 160 consecutive bilateral keratoconus patients (mean age 23.3 years, 63% male) from an Indian tertiary eye care center. Participants underwent a clinical examination and completed the IVI. Participants were divided into three groups based on the average of the steep keratometry (K) readings: mild (average Sim K < 45 diopters [D]), moderate (average Sim K 45-52 D), and severe (average Sim K > 52 D). Rasch analysis was used to validate the IVI and the VRQoL scores thus obtained were compared across the disease groups.RESULTS. The majority (63%) of patients had severe, while the remainder (37%) had moderate keratoconus. Rasch analysis demonstrated the validity of the IVI to assess VRQoL through two subscales: vision-specific functioning (VF) and emotional well-being (EWB). There was no significant difference in VF (mean change À0.16, P ¼ 0.55) and EWB scores (mean change À0.32, P ¼ 0.23) between moderate and severe keratoconus groups.CONCLUSIONS. The revised IVI subscales have interval-level measurement properties, which support their suitability to measure VRQoL in this keratoconus sample. Patients with moderate or severe keratoconus had similar, but higher VRQoL scores as assessed by the revised IVI subscales, indicating lack of impact of the disease on their VRQoL. However, this does not exclude the possibility of finding an impact in other populations.

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“…The life impact of repeat intervention, and slow, often incomplete, visual rehabilitation after transplantation should not be underestimated. 12 Transplantation costs, and evidence for reduced quality of life in contact lens wearers, 13 underline the need for a new, more proactive approach to keratoconus management.…”

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confidence: 99%

New clinical pathways for keratoconus

Gore

Shortt

Allan

2012

Eye

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Pre-2000, the clinical management of keratoconus centred on rigid contact lens fitting when spectacle corrected acuity was no longer adequate, and transplantation where contact lens wear failed. Over the last decade, outcome data have accumulated for new interventions including corneal collagen crosslinking, intracorneal ring implantation, topographic phototherapeutic keratectomy, and phakic intraocular lens implantation. We review the current evidence base for these interventions and their place in new management pathways for keratoconus under two key headings: corneal shape stabilisation and visual rehabilitation.

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Quality of Life in Keratoconus Patients After Penetrating Keratoplasty

Cited by 43 publications

References 15 publications

Assessment of Vision-Related Quality of Life in Dry Eye Patients

Assessment of Vision-Related Quality of Life in Dry Eye Patients

Assessment of the Impact of Keratoconus on Vision-Related Quality of Life

New clinical pathways for keratoconus

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