Quality of life in individuals with cervical dystonia before botulinum toxin injection in a Brazilian tertiary care hospital

Queiroz, Mariana Ribeiro; Chien, Hsin Fen; Barbosa, Egberto Reis

doi:10.1590/s0004-282x2011000700010

Cited by 15 publications

(9 citation statements)

References 19 publications

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“…The findings suggest that the proportion of female patients diagnosed with CD was higher than for male patients, and females had an earlier average age of onset, which is consistent with findings from the wider literature 4–9,28. Comorbidities were frequently reported in patients with CD, and several publications have focused on anxiety and depression 13,29,30.…”

Section: Discussionsupporting

confidence: 85%

A retrospective study to assess resource utilization in patients with cervical dystonia in the United Kingdom

Raluy-Callado¹,

Gabriel²,

Dinet³

et al. 2015

NDT

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PurposeCervical dystonia (CD) is a hypertonic condition caused by damage to the central nervous system. Very few studies have assessed the overall economic burden of the disease. The objective of this study was to describe the utilization of health care resources of patients with CD in the UK primary care setting, using a large population-based database.Patients and methodsAdults with a first diagnosis of CD between January 1, 2007 and January 31, 2011, who were registered to a general practitioner (GP) practice contributing to The Health Improvement Network (THIN), were included. Sociodemographic and clinical characteristics were assessed at the time of diagnosis. Health care resource utilization and pharmacological treatment were investigated at the end of the first and second year after diagnosis.ResultsOverall, 4,024 newly diagnosed patients with CD were identified, with average age at diagnosis of 45 years old; 65.3% were female. Depression in the year prior to diagnosis was the most common comorbidity. Primary care utilization was high in the first year, with 99.2% of patients visiting their GP (on average 6.2 times), and 43% visiting a nurse (on average 2.5 times). Patients were most commonly referred to an orthopedic surgeon, and 15.9% reported at least one physiotherapy visit. In the second year, utilization was similar. Prescriptions of at least one of the investigated treatments were found in 82.0% and 45.3%, in the first and second year, respectively.ConclusionFindings suggest a high number of new CD cases are being identified in primary care, but not all will be referred to secondary care. Health care resource utilization was compared with that of all patients registered in THIN, which is representative of the UK, and the adjusted usage of primary care resources was found to be similar to that of the THIN population.

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Section: Discussionsupporting

confidence: 85%

A retrospective study to assess resource utilization in patients with cervical dystonia in the United Kingdom

Raluy-Callado¹,

Gabriel²,

Dinet³

et al. 2015

NDT

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“…In addition, pain occurs in 75% of patients and contributes to a greater degree of disability . CD has also been associated with psychiatric disorders, including depression, anxiety, panic disorders, and social phobia . Furthermore, several studies have also demonstrated impaired health‐related quality of life (HRQoL) in CD …”

mentioning

confidence: 99%

“…3 CD has also been associated with psychiatric disorders, including depression, anxiety, panic disorders, and social phobia. [4][5][6][7] Furthermore, several studies have also demonstrated impaired health-related quality of life (HRQoL) in CD. [8][9][10][11][12][13][14] Although there have been many rating scales developed for motor symptoms of CD, 15 only three of these, the Tsui scale, 16 the Cervical Dystonia Severity Scale (CDSS), 17 and the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS), have had clinimetric evaluation.…”

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confidence: 99%

Clinimetric testing of the comprehensive cervical dystonia rating scale

et al. 2016

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Objective To test the clinimetric properties of the Comprehensive Cervical Dystonia Rating Scale. Background This is a modular scale with modifications of the Toronto Western Spasmodic Torticollis Rating Scale (composed of three subscales assessing motor severity, disability and pain) now referred to as the revised Toronto Western Spasmodic Torticollis Scale-2.; a newly developed psychiatric screening instrument; and the Cervical Dystonia Impact Profile-58 as a quality of life measure. Methods Ten dystonia experts rated subjects with cervical dystonia using the comprehensive scale. Clinimetric techniques assessed each module of the scale for reliability, item correlation and factor structure. Results There were 208 cervical dystonia patients (73% women, age 59±10 years, duration 15±12 years). The internal consistency of the motor severity subscale was acceptable (Cronbach’s alpha = 0.57). Item to total correlations showed that elimination of items with low correlations (<0.20) increased alpha to 0.71. Internal consistency estimates for the subscales for disability and pain were 0.88 and 0.95 respectively. The psychiatric screening scale had a Cronbach’s alpha of 0.84 and satisfactory item to total correlations. When the subscales of the Toronto Western Spasmodic Torticollis scale -2 were combined with the psychiatric screening scale, Cronbach's alpha was 0.88, and construct validity assessment demonstrated four rational factors: motor, disability, pain and psychiatric disorders. The Cervical Dystonia Impact Profile-58 had an alpha of 0.98 and its construction was validated through a confirmatory factor analysis. Conclusions The modules of the Comprehensive Cervical Dystonia Rating Scale are internally consistent with a logical factor structure.

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“… 3 – 6 Apart from these, other factors, such as depression, ability to cope with the disease, severity and duration of dystonia, female gender, stigma, and poor financial situation, also play significant roles in determining the QoL of CD patients. 4 , 7 – 10 The negative impact of CD can be significant and is similar to Parkinson’s disease, multiple sclerosis, and stroke. 5 , 11 …”

Section: Introductionmentioning

confidence: 99%

Impact of Neu-botulinumtoxinA on the Severity and Quality of Life of Cervical Dystonia Patients

Jagota

Kaewwilai

Boonrod

et al. 2016

Tremor and Other Hyperkinetic Movements

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Quality of life in individuals with cervical dystonia before botulinum toxin injection in a Brazilian tertiary care hospital

Cited by 15 publications

References 19 publications

A retrospective study to assess resource utilization in patients with cervical dystonia in the United Kingdom

A retrospective study to assess resource utilization in patients with cervical dystonia in the United Kingdom

Clinimetric testing of the comprehensive cervical dystonia rating scale

Impact of Neu-botulinumtoxinA on the Severity and Quality of Life of Cervical Dystonia Patients

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