Quality of life in hemodialysis patients: hepatitis C virus infection makes sense

Afsar, Barış; Elsürer, Rengin; Sezer, Sıren; Özdemir, Nurhan

doi:10.1007/s11255-009-9576-3

Cited by 16 publications

(22 citation statements)

References 34 publications

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“…In agreement with our study, Afsar et al [4] found positive correlation between haemoglobin levels and the following SF-36 subscales: physical functioning, role-physical limitation, bodily pain, general health perception, vitality, social functioning, role emotional and mental health subscales, PCS and MCS.…”

Section: Discussionsupporting

confidence: 93%

“…In this group QOL was not affected by age, but affected by gender and males were found to have higher scores in role emotional, bodily pains and PCS compared to females. Afsar et al [4] demonstrated that the majority of the SF-36 subscales were lower in anti-HCV antibody positive HD patients compared with in anti-HCV antibody negative patients, with an independent association between anti-HCV antibody positivity and MCS of SF-36, but not with PCS, which was in agreement with our study.…”

Section: Discussionsupporting

confidence: 93%

“…Our findings were similar to the findings of Fabrizi et al [8] and Spiegel et al [15]. In contrast, Asfar et al [4] found that Kt/V was only correlated with the mental health subscale.…”

Section: Discussionsupporting

confidence: 92%

“…Moreover, ESRD has become worldwide public health problem [2] causing a high level of disability in different domains of the patients' lives, leading to impaired quality of life (QoL) [3]. Although there have been many advances in the treatment of end-stage renal disease (ESRD), mortality rates for ESRD patients remain several times higher than those of age-matched controls, and patients with ESRD continue to have significant impairments in quality of life (QOL), quality of life is related with morbidity and mortality in hemodialysis patients, and it is suggested that QOL should be considered in the regular monitoring of dialysis patients [4]. Hemodialysis patients infected with HCV often have poor shortterm clinical outcome, greater mortality, greater hospitalization rate, more significant protein-energy malnutrition and worse health -related quality of life [5].…”

Section: Introductionmentioning

confidence: 99%

“…It was well demonstrated that HCV had a negative impact on health-related quality of life (HRQOL). Why quality of life decreases in HCV infected patients is incompletely understood [4]. The aim of this study was is to assess health related quality of life (HRQoL) in hepatitis C Virus (HCV) seropositive hemodialysis Egyptian patients.…”

mentioning

confidence: 99%

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Quality of Life in Hepatitis C Virus Seropositive Hemodialysis Patients

Ezzat¹

2015

UNOAJ

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Background: Health-related quality of life (HRQOL) is a multidimensional concept that reflects a patient's perceived well-being. It was well demonstrated that HCV had a negative impact on (HRQOL). The aim of this study was to assess HRQOL in hepatitis C Virus (HCV) seropositive hemodialysis Egyptian patients and highlight possible factors affecting it.Patients and methods: : 200 ESRD patients on regular hemodialysis at Ain Shams University hospitals and National Institute of Nephrology and Urology were included in this study and divided into 2 equal groups of HCV Ab seronegative and seropositive. Both groups were subjected to full medical history taking and examination. Laboratory investigations included hemoglobin level, pre dialysis blood urea, creatinine, calcium, phosphorus, PTH, ALT, AST, albumin and viral markers. Dialysis adequacy using Kt/v. HRQOL was measured through Short Form 36 (SF-36). In each dimension the respondent receives a score from 0 to 100. The higher the score, the better the health.Results: Our study showed that HCV seropositive hemodialysis patients had compromised HRQOL in comparison to HCV seronegative patients which was found in most of SF-36 subscales with higher scores for employed patients compared to the unemployed and those with higher haemoglobin levels. High pre dialysis serum creatinine, dry weight and serum albumin had significant positive correlation with SF-36 scale scores. Elevated liver enzymes and dialysis adequacy had no significant correlation with SF-36 scale scores. A significant negative correlation was present between serum phosphate and PTH on overall HRQOL. Conclusion:HCV infection impairs HRQOL, in many aspects in hemodialysis patients. Better HRQOL is associated with male gender, younger age, employment, higher hemoglobin, higher pre dialysis serum creatinine and higher serum albumin. Prevention of HCV transmission by proper infection control measures reduces the economic burden and complications in hemodialysis. Keywords: IntroductionHealth-related quality of life (HRQOL) is a multidimensional concept that reflects a patient's perceived well-being and functioning in physical, psychological and social domains of health [1]. End-stage renal disease (ESRD) is a chronic restrictive illness that affects many aspects of patient's life. Moreover, ESRD has become worldwide public health problem [2] causing a high level of disability in different domains of the patients' lives, leading to impaired quality of life (QoL) [3]. Although there have been many advances in the treatment of end-stage renal disease (ESRD), mortality rates for ESRD patients remain several times higher than those of age-matched controls, and patients with ESRD continue to have significant impairments in quality of life (QOL), quality of life is related with morbidity and mortality in hemodialysis patients, and it is suggested that QOL should be considered in the regular monitoring of dialysis patients [4]. Hemodialysis patients infected with HCV often have poor shortterm clinical outcome,...

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Section: Discussionsupporting

confidence: 93%

Section: Discussionsupporting

confidence: 93%

“…Our findings were similar to the findings of Fabrizi et al [8] and Spiegel et al [15]. In contrast, Asfar et al [4] found that Kt/V was only correlated with the mental health subscale.…”

Section: Discussionsupporting

confidence: 92%

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

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Quality of Life in Hepatitis C Virus Seropositive Hemodialysis Patients

Ezzat¹

2015

UNOAJ

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Health-related quality of life among hemodialysis patients at El-Minia University Hospital, Egypt

et al. 2012

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Background Hemodialysis results in significant change in daily living, physical and psychological impairments, disruption of marital, family, and social life. Health-related quality of life (HRQOL) assessment helps to plan individual treatment strategies, and determine the efficacy, quality of medical and social care provided. Aim The focus of the study was to assess HRQOL of hemodialysis patients attending El-Minia University Hospital dialysis unit, determine the relation between HRQOL and some sociodemograghic factors and clinical disorders and also to compare HRQOL between patients performing hemodialysis for less than and more than 5 years. Subjects and methods The study is a cross-sectional hospitalbased study that included 170 hemodialysis patients; 81 males and 89 females, mean age 46.6±14.6 years. In all 59.4 % were rural residents. Data were collected by a questionnaire which included, demographic, social and medical data. Kidney Disease Quality of Life-36 (KDQOL-36) health survey was used for assessment of HRQOL. Results About two thirds (64 %) of the studied hemodialysis patients had physical and mental quality of life (QOL) scores below average level. HRQOL was lower in old, female, married, illiterate and non-worker hemodialysis patients. Hepatitis C positive (HCV), diabetic and anemic patients had decreased QOL scores. A longer duration of hemodialysis treatment was associated with reduced physical QOL. ConclusionThe most important sociodemographic factors affecting HRQOL were age, sex, education, occupation and marital status. The most important clinical disorders affecting QOL were anemia, HCV infection, sleep disturbances and diabetes. Increase awareness of hemodialysis patients and their caregivers about disabilities associated with hemodialysis treatment and educational programs to decrease the problems which the patients face and to increase the QOL.

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Pegylated interferon alpha-2a for treatment of chronic HCV infection in hemodialysis patients: a single Saudi center experience

2010

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Quality of life in hemodialysis patients: hepatitis C virus infection makes sense

Abstract: HCV infection impairs QOL, especially in mental aspects, in hemodialysis patients.

Cited by 16 publications

References 34 publications

Quality of Life in Hepatitis C Virus Seropositive Hemodialysis Patients

Quality of Life in Hepatitis C Virus Seropositive Hemodialysis Patients

Health-related quality of life among hemodialysis patients at El-Minia University Hospital, Egypt

Pegylated interferon alpha-2a for treatment of chronic HCV infection in hemodialysis patients: a single Saudi center experience

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