Quality of Life in Dementia: Impact of Cognition and Insight on Applicability of the SF-36

Geschke, Katharina; Fellgiebel, Andreas; Laux, Nina; Schermuly, Ingrid; Scheurich, Armin

doi:10.1016/j.jagp.2012.12.014

Cited by 22 publications

(16 citation statements)

References 30 publications

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“…Third, it is likely that lack of insight, or lack of engagement with their illness, could result in people with dementia under-reporting reduced QoL. Certainly, impaired insight provides less reliable ratings of QoL [48], and may even effect the reliability and validity of some self-report measures of QoL [49]. However, in absolute terms, as judged by the variance in the multivariate models, it is clear that the contribution of dementia severity to the QoL of people with dementia is minimal whatever the measurement used, be it self-or proxy-rated, or disease-specific or generic.…”

Section: Discussionmentioning

confidence: 99%

Disease severity accounts for minimal variance of quality of life in people with dementia and their carers: analyses of cross-sectional data from the MODEM study

et al. 2020

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Background: Due to the progressive nature of dementia, it is important to understand links between disease severity and health-related outcomes. The aim of this study is to explore the relationship between disease severity and the quality of life (QoL) of people with dementia and their family carers using a number of disease-specific and generic measures. Methods: In the MODEM cohort study, three-hundred and seven people with clinically diagnosed dementia and their carers were recruited on a quota basis to provide equal numbers of people with mild (standardised Mini-Mental State Examination (sMMSE), n = 110), moderate (sMMSE 10-19, n = 100), and severe (sMMSE 0-9, n = 97) cognitive impairment. A series of multiple regression models were created to understand the associations between dementia severity and the QoL of people with dementia and the QoL of their carers. QoL was measured using self-(DEMQOL, EQ-5D, CASP-19) and proxy-reports (DEMQOL-Proxy, EQ-5D) of disease-specific and generic QoL of the person with dementia. Carer generic QoL was measured by self-report (EQ-5D, SF-12). Results: Disease severity, as measured by the sMMSE, was not significantly associated with the QoL of the person with dementia or the carer (p > 0.05), even after controlling for potential confounding variables for self-reported instruments. Proxy measures (rated by the carer) differed systematically in that there were small, but statistically significant proportions of the variance of QoL was explained by severity of cognitive impairment in multiple adjusted models. We also found little in the way of statistically significant relationships between the QoL of people with dementia and that of their carers except between DEMQOL-Proxy scores and the carer EQ-5D scores and carer SF-12 mental sub-scores.

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Section: Discussionmentioning

confidence: 99%

Disease severity accounts for minimal variance of quality of life in people with dementia and their carers: analyses of cross-sectional data from the MODEM study

et al. 2020

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“…52 On the other hand, others found no significant association between insight (or lack thereof) and self-reported QOL in AD. How can this difference be explained?…”

Section: Different Underlying Frameworkmentioning

confidence: 98%

“…There is some evidence that anosognosia is indeed associated with QOL ratings in dementia 9,10 and that impaired insight might compromise the reliability of self-reported QOL. 52 On the other hand, others found no significant association between insight (or lack thereof) and self-reported QOL in AD. 7 Furthermore, proxies cannot take into account the nonobservable factors that codetermine the subjective world of the person with dementia to a considerable extent.…”

Section: Different Underlying Frameworkmentioning

confidence: 98%

Cognitive functioning and quality of life: Diverging views of older adults with Alzheimer and professional care staff

Dewitte

Vandenbulcke

Dezutter

2018

Int J Geriat Psychiatry

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Staff reports cannot simply substitute reports of the subjective experience of residents with Alzheimer, so both judgments should be taken into account to form an adequate picture of QOL. Staff might be guided more strongly by a cognitive point of view when evaluating QOL of residents with Alzheimer disease, while the latter might have shifted their evaluation standards to cope adequately with the challenges posed by their disease.

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“…The scoring for MHCS includes vitality, social functioning, role-emotional, and emotional wellbeing. A recent study found reliable and valid data for a broad spectrum of patients with dementia and concluded that the SF-36 is suitable for dementia (Geschke et al, 2013). In the current study, the patients filled in the SF-36 questionnaire.…”

Section: Assessment Of Health-related Quality Of Life (Hrqol)mentioning

confidence: 99%

The impact of depressive symptoms on health-related quality of life in patients with subjective cognitive decline, mild cognitive impairment, and Alzheimer's disease

Pußwald

Moser

Pflüger

et al. 2016

Int. Psychogeriatr.

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Quality of Life in Dementia: Impact of Cognition and Insight on Applicability of the SF-36

Cited by 22 publications

References 30 publications

Disease severity accounts for minimal variance of quality of life in people with dementia and their carers: analyses of cross-sectional data from the MODEM study

Disease severity accounts for minimal variance of quality of life in people with dementia and their carers: analyses of cross-sectional data from the MODEM study

Cognitive functioning and quality of life: Diverging views of older adults with Alzheimer and professional care staff

The impact of depressive symptoms on health-related quality of life in patients with subjective cognitive decline, mild cognitive impairment, and Alzheimer's disease

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