Quality of life in dementia patients in long-term care

Gonzalez-Salvador, Teresa; Baker, Alva; Hovanec, Linda; Roques, Carmel; Brandt, Jason; Steele, Cynthia D.

doi:10.1002/(sici)1099-1166(200002)15:2<181::aid-gps96>3.0.co;2-i

Cited by 270 publications

(205 citation statements)

References 26 publications

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“…There are also few longitudinal or cohort studies of HRQoL in dementia. Gonzalez-Salvador and colleagues 44 found that assisted-living residents with dementia reported consistently better HRQoL than those living in skilled nursing facilities, although the former group also had higher MMSE scores (mean 9.5 compared with 2.6). Ballard and colleagues 45 studied the impact of behaviour, ADL and taking psychotropic drugs on quality of life.…”

Section: Impact Of Dementia On Quality Of Lifementioning

confidence: 99%

Measurement of health-related quality of life for people with dementia: development of a new instrument (DEMQOL) and an evaluation of current methodology

Smith¹,

Lamping²,

Banerjee

et al. 2005

Health Technol Assess

510

520

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Section: Impact Of Dementia On Quality Of Lifementioning

confidence: 99%

Measurement of health-related quality of life for people with dementia: development of a new instrument (DEMQOL) and an evaluation of current methodology

Smith¹,

Lamping²,

Banerjee

et al. 2005

Health Technol Assess

510

520

View full text Add to dashboard Cite

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“…Depression in patients with AD is an important public health problem with substantial consequences for patients and their caregivers (Lyketsos and Olin 2002). Depressive symptoms in patients with AD have been linked to diminished quality of life (González-Salvador et al 2000), greater caregiver depression (Neundorfer et al 2001), and greater likelihood of physically aggressive behaviour (Lyketsos et al 1999). Because symptoms typical of depression such as apathy, insomnia, and weight loss may also be owed to dementia-related processes, its diagnosis in dementia is difficult (Brodaty and Luscombe 1996).…”

Section: Introductionmentioning

confidence: 99%

Depressive symptoms in later life: differential impact of social support and motivational processes on depression in individuals with and without cognitive impairment

et al. 2014

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This study investigates the role of a motivational process based on a composite of four subcomponents (self-efficacy, decision regulation, activation regulation and motivation regulation), as a mediator of the relationship between social support and depression assessed with the Geriatric Depression Scale in cognitively impaired and unimpaired individuals. Participants were 229 adults with a mean age of 74 years (range: 52-94 years). The sample comprised 64 participants diagnosed with mild cognitive impairment (MCI), 47 participants diagnosed with earlystage Alzheimer's disease (AD), and a group of 118 participants without any cognitive impairment. In this crosssectional study, bivariate correlations and linear regression models were used to assess the association between the predictor variables and depression. Linear regression models were controlled for age, gender, education, cognitive status, cognitive impairment and activities. In the total Based on these findings, it can be argued that the impact of social support on depressive symptoms is attenuated by cerebral deterioration in cognitively impaired individuals, while motivational processes remain relevant.

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“…[2][3][4] These symptoms can present as a psychiatric syndrome, such as major depression, or can occur in isolation. In dementia, neuropsychiatric symptoms are a major source of suffering to both patients and caregivers by interfering with sleep, 5 impairing quality of life, 6 leading to institutional placement, 7 and compounding caregiver financial burden and emotional stress. 8 While patients affected by dementia and TBI independently are at increased risk for neuropsychiatric symptoms, no published data have examined the question of whether people with dementia who have sustained a TBI in the past are at increased risk for developing neuropsychiatric symptoms.…”

mentioning

confidence: 99%

Neuropsychiatric Symptoms in Dementia Patients With and Without a History of Traumatic Brain Injury

Rao

Rosenberg²,

Miles³

et al. 2010

Journal of Neuropsychiatry

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The authors aim to determine if a history of traumatic brain injury (TBI) assessed before dementia onset is associated with a higher risk of neuropsychiatric symptoms after dementia onset. A population-based incident series of people with dementia were assessed for TBI prior to onset of dementia and for neuropsychiatric symptoms after the onset, using the Neuropsychiatric Inventory. Participants with predementia TBI were more likely to exhibit disinhibition (12.7%Address correspondence to Vani Rao, M.D., Division of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry, Johns Hopkins University, 5300 Alpha Commons Dr., 4th Floor, #444, Baltimore, MD 21224; vrao@jhmi.edu. These results were presented as a poster by DP at Northeastern Ohio Universities College of Medicine's Summer Research Fellowship Program on 9/3/08 in Rootstown, Ohio, and as an oral presentation at Summa Health System on 1/8/09 in Akron, Ohio. DP is a Medical Student Training in Aging Research (MSTAR) scholar and presented these results at the 2009 American Geriatric Society Annual Scientific Meeting. While patients affected by dementia and TBI independently are at increased risk for neuropsychiatric symptoms, no published data have examined the question of whether people with dementia who have sustained a TBI in the past are at increased risk for developing neuropsychiatric symptoms. Given that dementia and TBI are both associated with damage to the frontal cortex and associated frontal-subcortical circuits, and damage to these circuits from a variety of insults predisposes patients to psychopathology, 9 we hypothesized that, in persons with dementia, TBI prior to the onset of dementia would be a risk factor for increased neuropsychiatric symptoms associated with frontal lobe damage such as disinhibition, irritability, depression, apathy, and aggression. We examined this question in a population-based study of persons with dementia whose history of TBI was assessed prior to the onset of dementia and in whom dementia-onset was assessed prospectively (incident cohort). NIH Public Access METHODSThis is a prospective study involving persons with incident dementia who took part in the Cache County Study on Memory, Health, and Aging (CCSMHA). The CCSMHA is an ongoing population-based study of the epidemiology and progression of dementia. The study has been approved by Institutional Review Boards at Duke University Medical Center, Johns Hopkins University, and Utah State University. Informed consent was obtained from either the study participants or appropriate next of kin. This study has been described previously. 10,11 Briefly, a total of 5,092 respondents (5,677 were invited) ages 65 years and older participated in the study. All participants underwent a multistage screening and assessment for prevalent dementia (Wave 1). Those with dementia in Wave 1 and those that did not develop dementia or dropped out between Waves 1 and 3 were excluded from these analyses (n=4,265). TBI AssessmentHead injury was assessed prior to the onse...

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Quality of life in dementia patients in long-term care

Cited by 270 publications

References 26 publications

Measurement of health-related quality of life for people with dementia: development of a new instrument (DEMQOL) and an evaluation of current methodology

Measurement of health-related quality of life for people with dementia: development of a new instrument (DEMQOL) and an evaluation of current methodology

Depressive symptoms in later life: differential impact of social support and motivational processes on depression in individuals with and without cognitive impairment

Neuropsychiatric Symptoms in Dementia Patients With and Without a History of Traumatic Brain Injury

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