Quality of life in children with kidney transplant: Systematic review

Araújo, Noélia Souza Santos; Pereira, Rogério Rodrigues Floriano; Fram, Dayana Souza; Hino, Paula; Longo, Maria Cristina Barbosa; Taminato, Mônica

doi:10.1590/0034-7167-2018-0464

Cited by 6 publications

(3 citation statements)

References 22 publications

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Section: Discussionmentioning

confidence: 99%

“…This review aimed to collate the existing literature examining QoL among adults who underwent SOT in childhood. While past reviews have summarized findings of QoL among pediatric SOT recipients, 43,44 the current study is the first to systematically explore long‐term QoL outcomes of this population into adulthood. Specifically, this review sought to synthesize existing literature examining a broad definition of QoL, including overall or total QoL, as well as specific domains of QoL, such as physical functioning, psychological functioning, and social functioning.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Quality of life and psychosocial outcomes of adults who were pediatric solid organ transplant recipients: A systematic review

Durish

Lin

Pol

et al. 2022

Pediatric Transplantation

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Background The number of pediatric SOT recipients surviving into adulthood is increasing. Thus, understanding their psychosocial and QoL outcomes is important. We conducted a systematic review to collate existing literature examining QoL outcomes (physical functioning, psychological functioning, social functioning), as well as risk and protective factors associated with QoL, among adults who underwent SOT during childhood. Methods A systematic search of five databases, from inception to January 6, 2021, was conducted to identify articles that reported on QoL outcomes for adults (≥18‐year of age) who received a SOT during childhood (<19‐year of age). Results Twenty‐five articles met inclusion criteria. Studies examined QoL across a range of SOT populations (liver, kidney, heart). QoL and psychosocial outcomes were variable; however, the majority of studies indicated QoL in this population to be similar to the general population, or at least similar to other chronic illness groups, with the exception of physical and social functioning. Factors related to a more optimal medical course, younger age at transplant and follow‐up, and positive psychosocial functioning, were found to be predictive of better QoL outcomes. Conclusions While several studies indicated QoL to be similar to the general population, the literature is limited in both quantity and quality. No study employed prospective, longitudinal methodologies to systematically evaluate QoL over time and few studies utilized normative‐based measures of QoL. Furthermore, several SOT groups were under‐represented in the literature (e.g., lung, intestine, multi‐visceral). Nonetheless, findings have implications for intervention and clinical decision‐making.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Quality of life and psychosocial outcomes of adults who were pediatric solid organ transplant recipients: A systematic review

Durish

Lin

Pol

et al. 2022

Pediatric Transplantation

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“…As principais causas de DRCT nessa população são as glomerulonefrites crônicas, malformações urológicas, displasias renais e a Doença Renal Crônica (DRC) de etiologia desconhecida, porém as mais frequentes são a sepse, a lesão renal aguda, diarreia, malária e síndrome hemolítico-urêmica (SHU). [4] O caso apresentado a seguir versa sobre uma paciente pediátrica, que foi submetida a um transplante renal com nefrectomia peroperatória devido à glomeruloesclerose segmentar e focal (GESF) do subtipo colapsante, que acarretava hipertensão arterial sistêmica (HAS) grave chegando a cursar com síndrome da encefalopatia posterior reversível (PRES).…”

Section: Introductionunclassified

Transplante renal pediátrico por HAS grave em caso de GESF colapsante: um relato de caso / Pediatric kidney transplantation for severe NASH in a case of collapsing GESF: a case report

Vieira¹,

Rocha²,

Duarte³

et al. 2021

Braz. J. Hea. Rev.

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Quality of life of transplanted children and their parents: a cross-sectional study

Duvant

Fillat

Garaix

et al. 2021

Orphanet J Rare Dis

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Background Transplantation is a saving therapeutic that has heavy consequences. The quality of life (QoL) of transplanted children and their parents has been little studied and should help physicians better manage these patients. The objectives of the study were to assess: (1) the QoL of transplanted children and parents and compare it with that of children with other chronic conditions associated with long-term consequences, and (2) potential variables modulating the QoL. Methods This cross-sectional study was performed in a multidisciplinary paediatric unit (Timone Hospital, Marseille, France). Children were less than 18 years old; had a liver, kidney or heart transplant; and had a time since transplantation of 1–10 years. Socio-demographics and clinical data were recorded from medical forms. The QoL was assessed using the VSP-A (Vécu et Santé Perçue de l’Adolescent et de l’Enfant) and the WhoQoL self-reported questionnaires. Results Forty-five families were included (response rate: 76%). The transplanted organs were the liver for 20 children, the kidney for 15 children, and the heart for 10 children. The QoL of transplanted children reported by their parents was better than that of children with inborn errors of metabolism and similar to that of childhood leukaemia survivors. The QoL of parents of transplanted children was better than that of parents of children with inborn errors of metabolism and did not differ from French norms. The QoL did not differ according to the nature of the transplanted organ, sex or the main sociodemographic data. The main modulators decreasing QoL were residual treatment level, medications switch and the presence of another regular treatment. Conclusion Transplanted children and their families reported a fairly preserved QoL compared to children with other chronic health conditions. Special attention should be given to QoL modulators related to therapeutic management (medication switches, regular treatments) that might be amenable to improve the QoL. Trial registration Ethics committee of Aix-Marseille University, France (reference number: 2014-08-04-03, 24/4/2015; https://www.univ-amu.fr/fr/public/comite-dethique).

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Quality of life in children with kidney transplant: Systematic review

Cited by 6 publications

References 22 publications

Quality of life and psychosocial outcomes of adults who were pediatric solid organ transplant recipients: A systematic review

Quality of life and psychosocial outcomes of adults who were pediatric solid organ transplant recipients: A systematic review

Transplante renal pediátrico por HAS grave em caso de GESF colapsante: um relato de caso / Pediatric kidney transplantation for severe NASH in a case of collapsing GESF: a case report

Quality of life of transplanted children and their parents: a cross-sectional study

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