Quality of life in adult hematopoietic cell transplant patients at least 5 yr after treatment: a comparison with healthy controls

Abstract

Patients who had survived their HCT for more than 5 yr did generally well in terms of global QOL. This is consistent with Kiss et al. (J Clin Oncol 2002;20:2334-2343), who found that chronic myeloid leukemia patients who were alive at least 10 yr after HCT report lower physical functioning in comparison to healthy controls. Problems in the areas of social functioning and financial difficulty can possibly be addressed by intensive rehabilitation processes integrating patients, family members and significant others. Interdisciplinary (medical, psychological and social) treatment of patients should not come to an end after the acute phase of the illness but should continue during check-ups following transplantation.

Quality of life and social integration after allogeneic hematopoietic SCT

“…2,4,18,23 However, even if HRQL analyses have not always been done with the same instruments, a high level of satisfaction with life quality and a progressive improvement over time has been frequently described. [1][2][3][5][6][7]23,24,26 It has been suggested that full recovery after HSCT may be a 3-to 5-year process. 3,7,24 Indeed, Kopp et al 26 observed in a investigation with the EORTC QLQ-C30 and FACT-BMT questionnaires that HRQL improves significantly within 1 year after HSCT.…”

“…[1][2][3][5][6][7]23,24,26 It has been suggested that full recovery after HSCT may be a 3-to 5-year process. 3,7,24 Indeed, Kopp et al 26 observed in a investigation with the EORTC QLQ-C30 and FACT-BMT questionnaires that HRQL improves significantly within 1 year after HSCT. In the present study, however, a significant correlation between HRQL and follow-up time was not observed.…”

“…[1][2][3] Information about health-related quality of life (HRQL) provides a broader understanding of the patient's status after treatment beyond simple diseasefree survival time. Hence, HRQL is now considered an index of the effectiveness of treatment and should become an integral component in the assessment of medical outcome.…”

“…Awareness of long-term effects (including psychosocial distress) that may affect HRQL can also guide program revisions to decrease potential problematic side effects. 1,[3][4][5][6][7] The aim of this study was to assess HRQL using the Functional Assessment of Cancer Therapy scale with specific modules for BMT (FACT-BMT) and the European Organization for Research and Treatment of Cancer (EORTC QLQ-C30) questionnaires in patients of a single institution after allogeneic HSCT and free of disease at the time of evaluation. These two instruments focus possibly on different aspects of HRQL.…”

Kwaliteit van leven en zingeving bij chronische lymfatische leukemie

“…Dit is zeker van belang voor patiën-ten die lijden aan een chronische en ongeneeslijke ziekte waarbij behandelmethoden geen effect hebben op overlevingskansen, maar eerder worden toegepast om de symptomen terug te dringen en een terugval in het ziekteproces te voorkomen. Zo wees een eerdere studie uit dat patiënten die aan deze ziekte lijden de KvL aanzienlijk kunnen verbeteren door effectiever om te gaan met de symptomen van de ziekte en door de psycho-oncologische bijstand die ze daarbij ontvangen (Kopp et al, 2005).…”