Quality of life in adolescents with epilepsy, cerebral palsy, and population norms

Boldyreva, Uliana; Streiner, David L.; Rosenbaum, Peter; Ronen, Gabriel M.

doi:10.1111/dmcn.14450

Cited by 18 publications

(19 citation statements)

References 29 publications

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“…The quality of life is determined by the functioning of a person; therefore, it is especially important among adolescents to diagnose any relationships between the quality of life and health condition. Negligence in care over children and adolescents at all stages of development has a multitude of detrimental effects on the health, both social and economic [16].…”

Section: Discussionmentioning

confidence: 99%

Quality of life, health, eating habits and physical development of middle school adolescents in the Świetokrzyskie

Jasińska¹,

Strzelecka²,

Chmielewski³

et al. 2021

Ann Agric Environ Med.

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Introduction and objective. Measurement of the health-related quality of life is currently one of the significant methods of self-evaluation of heath, enabling the detection of disorders in the biopsychosocial functioning of children and adolescents. The aim of the study was to establish significant relationships between the subjective sense of the health-related quality of life, eating habits and objective parameters of physical development among a group of adolescents. Materials and method. The study applied a diagnostic survey methodology with the use of the KIDSCREEN-52 questionnaire, the Health Behaviour in School-aged Children (HBSC) questionnaire, anthropometric measures of choice, and a selfconstructed questionnaire. The significance level was set at p<0.05. The collected data was gathered and analyzed using Statistica 10.0 PL. Results. Three distinct groups of adolescents with a varying subjective sense of the quality of life were identified. The frequency of basic meal consumption among participants showed some abnormalities. This concerned breakfast in particular, which was consumed before going to school by over half of the participants (63.61%), with boys (70.07%) eating it significantly more frequently than girls (57.83%). Indices based on weight-to-height ratios, such as: BMI, Rohrer's Index and Slender Index were significantly greater in value among boys compared with girls. Conclusions. Adolescents from the Świętokrzyskie region, for the most part exhibited a high subjective sense of the quality of life. The physical development of the participants, as far as basic anthropometric characteristics are concerned, was mostly appropriate and consistent with a high subjective sense of the quality of life and exhibited eating habits.

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Section: Discussionmentioning

confidence: 99%

Quality of life, health, eating habits and physical development of middle school adolescents in the Świetokrzyskie

Jasińska¹,

Strzelecka²,

Chmielewski³

et al. 2021

Ann Agric Environ Med.

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“…Епілепсія -група поширених медичних станів, головною ознакою яких є повторювані епілептичні напади. У людини вона може супроводжуватися супутніми розладами, серед яких депресивні та тривожні стани [1] з відповідним порушенням емоційної регуляції [2], що істотно знижують якість життя [3]. Проте нині існує досить мало даних щодо механізмів супутніх до епілепсії психіатричних розладів, і відповідно пошук шляхів їх корекції наразі є достатньо утрудненим [4].…”

Section: вступunclassified

Pharmacological Blockade of Acid Sensing Ion Channels Normalizes Emotionally Conditioned Learning Disturbed Due to Epileptic Status

Fedoriuk¹,

Stefanenko²,

Bohovyk³

et al. 2020

Fiziol Zh

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The effect of pharmacological blockade of ASIC1a channels on emotionally conditioned learning in rats with lithiumpilocarpine model of temporal lobe epilepsy was studied. The development of status epilepticus is known to impair both contextual and stimulated emotional learning. In our experiments, the painful effect was directly accompanied by freezing in animals of all groups, however, under conditions of induced epilepsy, its duration was shorter, and blocking ASIC1a channels neutralized this difference. The induction of epilepsy disrupted both contextual and stimulated emotional learning. Suppression of ASIC1a channels partially restored this process in animals with induced epilepsy. This means that pharmacological blocking of ASIC1a channels can have a positive therapeutic effect in correcting the emotional disorders associated with temporal lobe epilepsy.

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“…[2][3][4][5][6][7] These conditions can contribute to reduced quality of life in some children with epilepsy, 8,9 although quality of life for these young people is complex and remains an area of active research. [10][11][12] Researchers continue to explore which factors are most important to supporting quality of life in young people with epilepsy. 9,[13][14][15] To date, results indicate that parental and peer support, clinical seizure burden, and low verbal cognitive abilities all affect quality of life, 9,14,16 both directly and indirectly via child mental health.…”

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confidence: 99%

Self‐esteem mediates mental health outcomes in young people with epilepsy

et al. 2021

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Summary Objective To evaluate the extent to which self‐esteem mediates the impacts of epilepsy‐specific and environmental factors on mental health outcomes in young people with epilepsy. Methods A prospective cohort of 480 young people with epilepsy and their families participated in five visits over 28 months. We collected data on clinical seizure burden, cognitive comorbidity, peer and parental support, self‐esteem, and self‐reported mental health symptoms. We used structural equation modeling to specify and test relationships among these constructs simultaneously. Direct, indirect, and total effects were estimated with confidence intervals constructed through bias‐corrected bootstrapping. Results Self‐esteem mediated the effects of clinical seizure burden (β = 0.23, 95% confidence interval [0.05, 0.42]) and peer support (β = −0.15, 95% CI [−0.28, −0.03]) on mental health. There were no mediating effects of parental support (β = −0.07, 95% CI [−0.14, 0.00]) or cognitive comorbidity (β = −0.01, 95% CI [−0.02, 0.01]) on mental health. Significance We found evidence that self‐esteem mediates the impact that both clinical seizure burden and peer support have on mental health outcomes, indicating that assessment of and interventions targeting self‐esteem may be appropriate for young people with epilepsy. Supporting self‐esteem could mitigate negative influences on mental health, whether from resistant epilepsy or low peer support.

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Quality of life in adolescents with epilepsy, cerebral palsy, and population norms

Cited by 18 publications

References 29 publications

Quality of life, health, eating habits and physical development of middle school adolescents in the Świetokrzyskie

Quality of life, health, eating habits and physical development of middle school adolescents in the Świetokrzyskie

Pharmacological Blockade of Acid Sensing Ion Channels Normalizes Emotionally Conditioned Learning Disturbed Due to Epileptic Status

Self‐esteem mediates mental health outcomes in young people with epilepsy

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