Quality of life, fatigue and seizure severity in people living with epilepsy in a selected Nigerian population

Akosile, Christopher Olusanjo; Anomneze, John Uche; Okoye, Emmanuel Chiebuka; Adegoke, Babatunde O. A.; Uwakwe, Richard; Okeke, Emeka

doi:10.1016/j.seizure.2020.10.029

Cited by 6 publications

(2 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Dealing with the difficulties of the disease remains a considerable challenge for PWE, as well as their relatives [8]. Quality of life (QoL) is often disturbed and can be influenced by many factors, like anti-seizure medication side effects, the sociocultural environment, and various disease-related factors [9][10][11]. Furthermore, epilepsy is surrounded by a number of mental illnesses (anxiety, depression) and social issues that make managing it more difficult [12] and have a substantial negative impact on quality of life [13].…”

Section: Introductionmentioning

confidence: 99%

Quality of life and associated factors among people with epilepsy in Ethiopia: a systematic review and meta-analysis

Andualem,

Melkam,

Tadesse

et al. 2024

BMC Public Health

View full text Add to dashboard Cite

Background Epilepsy is a global health and economic burden with major problems that have an impact on physical, psychological, and social activities. Quality of life (QoL) is often disturbed and can be influenced by many factors, like anti-seizure medication side effects, the sociocultural environment, and various disease-related factors. The aim of this systematic review and meta-analysis is to provide an overview of the most recent information available regarding the pooled prevalence of poor quality of life and associated factors among adult people with epilepsy in Ethiopia. Methods The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) is an appropriate set of guidelines for reporting systematic reviews and meta-analyses. This systematic review and meta-analysis protocol was registered on the International Prospective Register of Systematic Reviews (PROSPERO) with CRD42024527914. To find publications for the systematic review and meta-analysis, we used both manual and electronic searches. The publications were searched by PubMed, MEDLINE, EMBASE, Cochrane Library, Scopus, and other grey publications were searched by Google Scholar. The Joanna Briggs Institute (JBI) for cross-sectional study quality assessment was employed to evaluate the methodological quality of the studies included in this review. The data was extracted in Microsoft Excel, and then it was exported into STATA 11.0 for analysis. A funnel plot and an objective examination of Egger’s regression test were used to check for publication bias. Results We have included 7 studies conducted in Ethiopia with 2123 study participants, of whom 1163 (54.78%) were male individuals, and 1196 (56.34%) of the participants were living without marriage (either single, divorced, or widowed). The pooled prevalence of poor quality of life among people with epilepsy in Ethiopia is 45.07 (95% CI: 39.73–50.42%). Further, in subgroup analysis regarding the assessment tool of poor quality of life of people with epilepsy, QOLIE-31 accounted for 50.05% (95%CI: 46.65–53.45) and WHO QOL BREF accounted for 39.72% (95%CI: 27.67–51.78). Among the associated factors, being unable to read and write, anxiey and depression were significantly linked to the quality of life of people with epilepsy. Conclusion This review found that there was a high pooled prevalence of poor quality of life related to people with epilepsy in Ethiopia. This study may provide further information to concerned bodies that do early screening and manage the quality of life of individuals with epilepsy. Also, screening and intervention for anxiety and depression problems should be considered in regular epilepsy care management.

show abstract

Section: Introductionmentioning

confidence: 99%

Quality of life and associated factors among people with epilepsy in Ethiopia: a systematic review and meta-analysis

Andualem,

Melkam,

Tadesse

et al. 2024

BMC Public Health

View full text Add to dashboard Cite

show abstract

“… 11 However, premature mortality is not the only consequence of stroke and epilepsy; both conditions also affect the health-related quality of life (HRQoL) of individuals. 12 , 13 Measuring the health status of individuals is important because health status is considered in any equation that defines the benefits or effectiveness of interventions and is used to evaluate health care in terms of patient outcomes, to describe population health levels, and to study changes in health over time. 14 …”

mentioning

confidence: 99%

Estimating Utility Values for Health States of Nigerian Individuals with Stroke or Epilepsy Using the SF-36: A Brief Report on the Results of a Cross-Sectional Survey

Gebrye,

Akosile,

Okoye

et al. 2024

MDM Policy & Practice

View full text Add to dashboard Cite

Background. Stroke and epilepsy are the most common neurologic conditions affecting individuals. The Short Form Six-Dimension Health Index (SF-6D) is a preference-based measure of health developed to estimate utility values from the SF-36. This study estimated utility values for health states of Nigerian individuals with stroke or epilepsy using the SF-36. Methods. SF-36 responses from 125 and 69 individuals with stroke and persons with epilepsy, respectively, were transformed into health state utility values using the SF-6D algorithm. The Excel program developed by Brazier and colleagues was used to generate the SF-6D utility score estimated using a set of parametric preference weights. The health state utility values were determined using ordinal health state and standard gamble valuation techniques. Results. Mean ( s) ages of the stroke and epilepsy participants were 63.1 (11) and 39.6 (16) y, respectively. The mean ( s) utility scores for stroke and epilepsy were 0.52 (0.10) and 0.65 (0.1) for standard gamble and 0.48 (0.13) and 0.68 (0.11), respectively, using the ordinal health state paradigm. The mean ( s) utility of stroke (female = 0.46 [0.15]; male = 0.50 [0.12]) and epilepsy (female = 0.65 [0.13], male = 0.69 [0.11]) participants were reported. The mean ( s) annual episodes of seizure was 18.7 (39). Conclusions. To our knowledge, this is the first study to suggest that females with stroke and those with epilepsy considered their health to be poorer than that of their male counterparts. The significance of our findings is that they may be helpful for researchers, policy makers, and clinicians by providing input into economic evaluations to facilitate resource allocation for stroke survivors and people living with epilepsy to improve their health outcomes and reduce the huge burden associated with the conditions. Highlight We estimated a health state utility value for stroke and epilepsy to aid researchers and public health policy makers in conducting health economic analysis and outcomes research.

show abstract

Effects of progressive muscle relaxation exercises on patients with epilepsy on level of depression, quality of sleep, and quality of life: A randomized controlled trial

Özden

Turan

2023

Seizure: European Journal of Epilepsy

View full text Add to dashboard Cite

Quality of life, fatigue and seizure severity in people living with epilepsy in a selected Nigerian population

Cited by 6 publications

References 42 publications

Quality of life and associated factors among people with epilepsy in Ethiopia: a systematic review and meta-analysis

Quality of life and associated factors among people with epilepsy in Ethiopia: a systematic review and meta-analysis

Estimating Utility Values for Health States of Nigerian Individuals with Stroke or Epilepsy Using the SF-36: A Brief Report on the Results of a Cross-Sectional Survey

Effects of progressive muscle relaxation exercises on patients with epilepsy on level of depression, quality of sleep, and quality of life: A randomized controlled trial

Contact Info

Product

Resources

About