Quality of life during formoterol treatment: comparison between asthma-specific and generic questionnaires. Canadian and the Dutch Formoterol Investigators

Molen, Thys van der; Sears, M.R.; Graaff, Casper S. de; Postma, D.S.; Jong, Betty Meyboom-de

doi:10.1183/09031936.98.12010030

Cited by 45 publications

(23 citation statements)

References 19 publications

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“…Other studies have also found that the average HRQL in mild-to-moderate asthma patients is close to that of the general population [24]. A strong link between asthma-related quality of life and disease severity has been reported [20,25], and this relationship was also observed in the current study.…”

Section: Discussionsupporting

confidence: 73%

Relationship between guideline treatment and health-related quality of life in asthma

Pont¹,

Molen²,

Denig³

et al. 2004

Eur Respir J

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The aim of this study was to compare the health-related quality of life (HRQL) of asthma patients treated according to the 1997 National Institute of Health (NIH) international asthma guideline and that of asthmatics receiving non-guideline treatment.The suitability of 146 asthmatics9 medication regimes was determined according to the 1997 NIH asthma guideline. Quality of life was assessed on a seven-point scale using the Asthma Quality of Life questionnaire.Just over half of the patients were not currently using the treatment considered necessary for controlling their asthma. Patients treated according to the guideline (n=72) had a significantly higher overall HRQL than patients with non-guideline treatment (5.7 versus 5.3). The differences were also significant for the subscales measuring symptoms and environmental exposure, but not for activities or emotional function.An association between non-guideline treatment and a poorer health-related quality of life in asthma patients treated in general practice was observed. This study supports the role of evidence-based guidelines in daily practice. Further studies are needed to determine if guideline treatment is responsible for the increase in health-related quality of life observed in this work. Eur Respir J 2004; 23: 718-722.

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Section: Discussionsupporting

confidence: 73%

Relationship between guideline treatment and health-related quality of life in asthma

Pont¹,

Molen²,

Denig³

et al. 2004

Eur Respir J

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“…However, the logarithmic mean scale score improved slightly but significantly in the second study. In previous studies, HQOLincreased slightly by 0.09 (1 1) or remained unchanged (1). Therefore the change in scale scores in this study was within the reported range of variation.…”

Section: Discussionsupporting

confidence: 51%

“…However, in the present study, a distribution approximating normal was found only in the logarithmic values and not in the raw scale scores. That frequency distribution of scale scores was not normally distributed was also recognized in the report by Molen et al (1). Wesuggest that comparison of distributions should be done in logarithmic values.…”

Section: Discussionmentioning

confidence: 96%

“…The mean scale score of 304 patients in the first study was 1.83 (range, 1.14-2.77). As shown in Fig.…”

Section: Distribution and Reproducibility Of Scale Scoresmentioning

confidence: 99%

“…On the other hand, measurement of health-related quality of life (HQOL)has increasingly been used to assess main outcome variables in clinical studies (1). With regard to bronchial asthma, there are international scales for HQOL assessments such as asthma quality of life questionnaire (AQLQ) (2), living with asthma questionnaire (LWAQ) (3) and others (4,5).…”

Section: Introductionmentioning

confidence: 99%

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Applicability of Hyland's Living with Asthma Questionnaire for Japanese Asthmatic Patients.

et al. 2000

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Objective To assess the applicability of Hyland's Living with Asthma Questionnaire (LWAQ,1991), one of the international health-related quality of life scales, for Japanese asthmatic patients with reference to its reproducibility and validity. Subjects and Methods The LWAQwas given to randomly selected asthmatic patients on two occasions separated by a 12-week interval. Results The mean scale score in the first study (n=304) was 1.83 (range, 1.14-2.77) and logarithmic values of the scores approached normal distribution. The scale scores in the first and second (n=158) studies were well correlated (r=0.81), however, the mean score decreased (0.08) significantly. The questions were further separated into ll domains. Thesex-domainwasnotable for a low response rate (68%), and scale scores in the sleep-, colds-and sex-domains in the first study varied considerably from those of the other domains. Frequency distributions of scores in the five constructs (Hyland 1996) were not normal and, with the exception of the colds construct, the relations amongthe remaining four constructs were similar to those previously reported (Hyland 1996). Conclusion Analysis using the meanscale score, domain and construct in the LWAQ is applicable to Japanese asthmatic patients.

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Incidence of occupational asthma by occupation and industry in Finland

Karjalainen¹,

Kurppa²,

Virtanen³

et al. 2000

Am. J. Ind. Med.

143

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Background Systematic research on occupation or industry‐specific incidence of occupational asthma (OA) is sparse. We calculated the incidence of notified OA by occupation, industry and causative agent in Finland for the years 1989–95. Methods The numbers of cases of reported OA were retrieved from the Finnish Registry of Occupational Diseases for the population between 20 and 64 years of age. The numbers of employed workers were retrieved from Statistics Finland. Incidence rates were calculated for each occupation, industry and the total workforce. Results Altogether 2602 cases of OA were notified and the mean annual incidence rate was 17.4 cases/100,000 employed workers. The incidence rate was the highest in bakers, other painters and lacquerers, veterinary surgeons, chemical workers, farmers, animal husbandry workers, other food manufacturing workers, welders, plastic product workers, butchers and sausage makers, and floor layers. Cases caused by animal epithelia, hairs and secretions or flours, grains, and fodders accounted for 60% of the total. Conclusions Estimation of occupation and industry‐specific incidence rates forms the basis for successful prevention of OA, but necessitates collection of data over several years from well‐established surveillance systems. Am. J. Ind. Med. 37:451–458, 2000. © 2000 Wiley‐Liss, Inc.

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Quality of life during formoterol treatment: comparison between asthma-specific and generic questionnaires. Canadian and the Dutch Formoterol Investigators

Cited by 45 publications

References 19 publications

Relationship between guideline treatment and health-related quality of life in asthma

Relationship between guideline treatment and health-related quality of life in asthma

Applicability of Hyland's Living with Asthma Questionnaire for Japanese Asthmatic Patients.

Incidence of occupational asthma by occupation and industry in Finland

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