Quality-of-Life Changes and Psychiatric and Neurocognitive Outcome After Heart and Liver Transplantation

Riether, Anne Marie; Smith, Susan L.; Lewison, Barbara; Cotsonis, George; Epstein, Charles M.

doi:10.1097/00007890-199209000-00012

Cited by 95 publications

(54 citation statements)

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“…It has been demonstrated that quality of life can be improved after transplantation in liver disease patients. [1][2][3][4] Previous investigations into quality of life among transplant recipients have primarily focused on the relation between medical treatment, course of transplantation (revisions, retransplantation, rejection), and patient quality of life. Some authors have observed that maladaptive coping strategies and the presence of high levels of anxiety/depression after transplantation can relate to poor outcomes and a poorer quality of life.…”

Section: O Ver the Last Decade Liver Transplantation Hasmentioning

confidence: 99%

Psychosocial Determinants of Quality of Life 6 Months After Transplantation: Longitudinal Prospective Study

Telles-Correia

Barbosa²,

Mega

et al. 2009

Transplantation Proceedings

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Objectives. We sought to investigate the psychosocial determinants of quality of life at 6 months after transplantation. Methods. A sample of liver transplant candidates (n ϭ 60), composed of consecutive patients (25% with familial amyloid polyneuropathy [FAP]) attending outpatient clinics was assessed in the pretransplant period using the Neo Five Factor Inventory, Hospital Anxiety and depression Scale (HADS), Brief COPE, and SF-36, a qualityof-life, self-rating questionnaire. Six months after transplantation, these patients were assessed by means of the SF-36. Results. Psychosocial predictors where found by means of multiple regression analysis. The physical component of quality of life at 6 months after transplantation was determined based upon coping strategies and physical quality of life in the pretransplant period (this model explained 32% of variance). The mental component at 6 months after transplantation was determined by depression in the pretransplant period and by clinical diagnoses of patients. Because FAP patients show a lower mental component of quality of life, this diagnosis explained 25% of the variance. Conclusions. Our findings suggested that coping strategies and depression measured in the pretransplant period are important determinants of quality of life at 6 months after liver transplantation.

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Section: O Ver the Last Decade Liver Transplantation Hasmentioning

confidence: 99%

Psychosocial Determinants of Quality of Life 6 Months After Transplantation: Longitudinal Prospective Study

Telles-Correia

Barbosa²,

Mega

et al. 2009

Transplantation Proceedings

View full text Add to dashboard Cite

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“…The SIP has been applied to study several diseases of varying severity (12)(13)(14)(15). While its psychometric properties are good and its overall validity reasonable, many of the items in the SIP measure extremely low levels of function; thus, the SIP may be more useful to assess HRQOL in those who are very ill. Because this instrument may lack the sensitivity to detect meaningful changes in HRQOL, particularly for patients with hepatitis C without cirrhosis, it is important to validate the SIP in patients with hepatitis C before its use in clinical trials.…”

Section: Health-related Quality Of Lifementioning

confidence: 99%

Outcomes Research in Chronic Viral Hepatitis C: Effects of Interferon Therapy

2000

Canadian Journal of Gastroenterology

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“…Most studies have demonstrated that quality of life is improved by transplantation of patients with liver disease. [1][2][3][4] Nevertheless, many authors debate when the improvement occurs. Most studies assess patients more than 6 months after transplantation.…”

mentioning

confidence: 99%

When Does Quality of Life Improve After Liver Transplantation? A Longitudinal Prospective Study

Telles-Correia

Barbosa²,

Mega

et al. 2009

Transplantation Proceedings

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Objectives. We sought to investigate the improvement in quality of life (mental and physical components) at 1 and 6 months after liver transplantation. Methods. A sample of liver transplant candidates (n ϭ 60), comprising consecutive patients attending outpatient clinics of a liver transplantation central unit (25% of the patients had familial amyloid polyneuropathy [FAP] and the remaining patents had chronic liver diseases), was assessed by means of the Short Form (SF)-36, Portuguesevalidated version, a self-rating questionnaire developed by the Medical Outcome Trust, to investigate certain primary aspects of quality of life, at 3 times: before, and at 1 and 6 months after transplantation. Results. We observed a significant improvement in quality of life (both mental and physical components) by 1 month after transplantation. Between the first month and the sixth month after transplantation, there also was an improvement in the quality of life (both mental and physical components), although only the physical components of quality of life was significantly improved. Conclusions. Our findings suggested that quality of life improved early after liver transplantation (1 month). Between the first and the sixth months, there only was a significant improvement in the physical quality of life.

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Quality-of-Life Changes and Psychiatric and Neurocognitive Outcome After Heart and Liver Transplantation

Cited by 95 publications

References 0 publications

Psychosocial Determinants of Quality of Life 6 Months After Transplantation: Longitudinal Prospective Study

Psychosocial Determinants of Quality of Life 6 Months After Transplantation: Longitudinal Prospective Study

Outcomes Research in Chronic Viral Hepatitis C: Effects of Interferon Therapy

When Does Quality of Life Improve After Liver Transplantation? A Longitudinal Prospective Study

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