2013
DOI: 10.1002/hed.23305
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Quality of life before and after total laryngectomy: Results of a multicenter prospective cohort study

Abstract: QOL decreases initially after laryngectomy; some QOL areas recover slowly over the course of the year after surgery, and some remain significantly worse than at baseline.

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Cited by 72 publications
(69 citation statements)
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References 48 publications
(70 reference statements)
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“…As such, TL is most commonly reserved for those who fail chemoradiation, have extensive disease with contiguous spread or cartilage invasion, or present with a nonfunctional larynx . Despite the accepted indications, TL is known to negatively impact patient quality of life in several domains including speech, eating, aesthetics, and social interactions …”
Section: Introductionmentioning
confidence: 99%
“…As such, TL is most commonly reserved for those who fail chemoradiation, have extensive disease with contiguous spread or cartilage invasion, or present with a nonfunctional larynx . Despite the accepted indications, TL is known to negatively impact patient quality of life in several domains including speech, eating, aesthetics, and social interactions …”
Section: Introductionmentioning
confidence: 99%
“…When laryngeal SCC recurs, salvage of limited recurrences may be attempted with organ‐sparing surgery . With more extensive recurrences, total laryngectomy is often the only option, with its sequelae of permanent tracheostoma, loss of laryngeal voice, and decreased quality of life . In case of an inoperable recurrence that persists, despite palliative surgical and nonsurgical treatments, the patient often dies of laryngeal cancer with locally progressing disease and its devastating effect on the quality of life.…”
Section: Introductionmentioning
confidence: 99%
“…Details of the study design have been published in previous papers . In brief, patients were approached before total laryngectomy [t1], before onset of rehabilitation (t2), at the end of rehabilitation (t3), and 1 year (t4), 2 years (t5), and 3 years (t6) after surgery.…”
Section: Methodsmentioning
confidence: 99%