Quality of Life Assessment in Retinoblastoma: A Cross‐Sectional Study of 122 Survivors from India

Batra, Atul; Kumari, Mamta; Paul, Reeja; Patekar, Mukesh; Dhawan, Deepa; Bakhshi, Sameer

doi:10.1002/pbc.25781

Cited by 31 publications

(59 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…12 An Indian study reported that because of differences in the medical and social support systems of pediatric patients with RB from those in Western societies, the differences in scores of the social and school dimensions between pediatric patients and the control group were statistically significant. 13 In our study, only the school dimension score in the PedsQL TM 4.0 of pediatric patients in the younger age group (5-7 years) was significantly lower than that of normal children, whereas the differences in scores of the social and school dimensions in the PedsQL TM 4.0 for 8-18-year-old children between the study group and the normal control group were both statistically significant. It has been shown that when the survival time of pediatric patients with cancer is longer, the quality of life is worse.…”

Section: Discussioncontrasting

confidence: 56%

“…The differences in these results were greater than those in the Indian study, which showed that the differences in quality of life between pediatric patients with unilateral and bilateral RB were not statistically significant. 13 In this study, the quality of life scores of pediatric patients with diagnosis ages ≤ 18 months were better than those of patients with diagnosis ages > 18 months. Some evidence has indicated that older diagnosis ages of pediatric patients with cancer are associated with more physiological and psychological problems in long-term cancer survivors.…”

Section: Discussionmentioning

confidence: 56%

“…The 40% eye salvage rate in the Dutch study samples might be the reason why the quality of life of Dutch pediatric patients with RB was close to that of normal children. 11,13 The differences in scores of the social and school dimensions in the PedsQL TM 4.0 between pediatric patients with RB and the control group were statistically significant. The differences in scores of these dimensions among Dutch pediatric patients with RB were not statistically significant, and only pediatric patients in the 12-18-yearold age range had certain difficulties in "peer relationship and social support."…”

Section: Discussionmentioning

confidence: 93%

“…12 Additionally, an Indian study with a large sample size showed that the quality of life of children with RB was significantly lower than that of normal children. 13 Current studies on subjects that include both children with RB with eye salvage and enucleation do not consider the presence of possible differences in quality of life between these two population groups. Eyes not only perform physiological functions such as vision but are also significant in the maintenance of appearance.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Quality of life in children with retinoblastoma after enucleation in China

Zhang

Gao

Shen

2018

Pediatric Blood & Cancer

View full text Add to dashboard Cite

Objective: To study the quality of life of Chinese pediatric patients with retinoblastoma (RB) after enucleation and the influencing factors.Methods: A questionnaire survey was performed on 71 cases of pediatric patients with RB after enucleation and 80 cases of healthy children, using the Pediatric Quality of Life Inventory 4.0 Generic Core Scales (PedsQL TM 4.0). Results:The social dimension scores, school dimension scores, and total scores for the PedsQL TM 4.0 among the pediatric patients with RB were statistically significantly lower than those of healthy children. The influencing factors were unilateral/bilateral affected eyes, diagnosis age, and ocular prosthesis satisfaction. Conclusion:Early discovery, timely treatment, increased eye salvage rate, and cosmetic effects of ocular prosthesis were key factors for increasing the quality of life of pediatric patients with RB.Attention should be paid to the health, social, and school development of pediatric patients with RB.

show abstract

Section: Discussioncontrasting

confidence: 56%

Section: Discussionmentioning

confidence: 56%

Section: Discussionmentioning

confidence: 93%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Quality of life in children with retinoblastoma after enucleation in China

Zhang

Gao

Shen

2018

Pediatric Blood & Cancer

View full text Add to dashboard Cite

show abstract

“…3 Despite the high cure rates, retinoblastoma survivors tend to have a poorer quality of life and have greater school absenteeism. 4 Further, pediatric cases of heritable retinoblastoma have an elevated risk for developing sarcoma and leukemia by age 14. 5 In adulthood, these children have an increased risk of chronic medical conditions including a second malignant neoplasm.…”

Section: Introductionmentioning

confidence: 99%

Residential Pesticide Exposures in Pregnancy and the Risk of Sporadic Retinoblastoma: A Report From the Children's Oncology Group

Omidakhsh

Ganguly

Bunin

et al. 2017

American Journal of Ophthalmology

View full text Add to dashboard Cite

Purpose To examine whether parental pesticide exposure contributes to the development of sporadic retinoblastoma. Design Case-control study. Methods Data were collected by a large multicenter study of sporadic retinoblastoma in which parents of 99 unilateral and 56 bilateral age matched case-control pairs were interviewed by telephone. Retrospective exposure information was collected on the type, location, timing and frequency of residential pesticide use. We used conditional logistic regression analyses to estimate odds ratios for maternal pesticide exposure in the month before or during pregnancy and to assess whether the type of product, and the circumstances under which it was applied, were associated with risk of disease. Results Unilateral retinoblastoma was associated with parental insecticide use (OR, 2.8; CI, 1.1–6.7) and the use of professional lawn or landscape services (OR, 2.8; CI, 1.0–8.2). For bilateral disease we observed large point estimates for several exposures but the small number of cases rendered these results uninformative i.e. resulted in wide confidence intervals. Whether parents used the pesticide inside vs. outside the home did not appear to modify risk estimates for unilateral retinoblastoma (OR, 2.5; CI, 0.9–7.0 vs. OR, 2.5; CI, 1.0–6.5), nor did the type, frequency, timing related to pregnancy or applicator of pesticide used influence estimates to an appreciable degree for disease. Conclusions Our results suggest that parental pesticide exposure before or during pregnancy may play a role in the development of childhood retinoblastoma. Retrospectively collected exposure data introduces the possibility of recall bias, therefore, results should be interpreted cautiously until additional studies are conducted.

show abstract

Vision-Targeted Health-Related Quality of Life in Adult Survivors of Retinoblastoma

et al. 2018

View full text Add to dashboard Cite

IMPORTANCE Retinoblastoma survivors are at risk for adverse oculo-visual outcomes. Limited data are available regarding long-term vision-targeted health-related quality of life (HRQoL) of adult retinoblastoma survivors.OBJECTIVE To examine vision-targeted HRQoL as reported on the 25-item National Eye Institute Visual Field Questionnaire for overall and specific scale scores among adult survivors of retinoblastoma.

show abstract

Quality of Life Assessment in Retinoblastoma: A Cross‐Sectional Study of 122 Survivors from India

Abstract: We found a significantly poorer QOL in retinoblastoma survivors with the psychosocial health domain being more affected than the physical domain. Age less than 18 months at diagnosis predicted better QOL.

Cited by 31 publications

References 18 publications

Quality of life in children with retinoblastoma after enucleation in China

Quality of life in children with retinoblastoma after enucleation in China

Residential Pesticide Exposures in Pregnancy and the Risk of Sporadic Retinoblastoma: A Report From the Children's Oncology Group

Vision-Targeted Health-Related Quality of Life in Adult Survivors of Retinoblastoma

Contact Info

Product

Resources

About