Quality of life as a predictor of morbidity, mortality, and resource utilization after solid organ transplant

Phillips, AL; Walker, E.L; Martin, Jill E.; First, M. Roy; Hanto, Douglas W.; Whiting, James F.

doi:10.1016/s0041-1345(00)02713-5

Cited by 13 publications

(7 citation statements)

References 1 publication

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“…First, in comparison with the only two other published cohort studies (20,21), ours was smaller than one study (21), and although our study had a much longer follow-up, deaths were fewer. As expected, there were several different causes of death in the present sample, but the subgroups were too small for meaningful analyses.…”

Section: Discussionmentioning

confidence: 61%

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Health-Related Quality of Life and Long-Term Survival and Graft Failure in Kidney Transplantation

2013

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Section: Discussionmentioning

confidence: 61%

“…far less information about the associations between HRQOL and mortality in kidney transplantation (20). A recent study of a large sample of transplant recipients showed that physical HRQOL dimensions were independently associated with survival after case-mix adjustment (21).…”

mentioning

confidence: 99%

Health-Related Quality of Life and Long-Term Survival and Graft Failure in Kidney Transplantation

2013

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“…In liver transplant recipients, SF-36 scores were significantly associated with rates of unemployment and disability post-transplant establishing construct validity [14]. Phillips et al demonstrated predictive validity of the SF-36 in liver transplant recipients by showing a significant correlation between pre-transplant SF-36 scores and post-transplant morbidity, mortality, and resource utilization [15]. The number of longitudinal studies using the SF-36 is limited; however, several studies have demonstrated responsiveness of this instrument to changes in health over time, as demonstrated by improvements in scores following transplant [16−19].…”

Section: Resultsmentioning

confidence: 99%

A review of quality of life instruments used in liver transplantation

Jay

Butt

Ladner

et al. 2009

Journal of Hepatology

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SUMMARYWith improvements in patient and graft survival after liver transplantation, recipient quality of life (QOL) has become an important focus of patient care and clinical outcomes research. To provide a better understanding of the instruments used to assess QOL in the adult liver transplant population, we conducted a systematic review of the MEDLINE database and Cochrane library. Our review identified 128 relevant articles utilizing more than 50 different QOL instruments. Generic health status instruments are the most commonly used, and among them the Medical Outcomes Study Short Form-36 (SF-36), the Hospital Anxiety and Depression Scale (HADS), and the Beck Depression Inventory (BDI) are the most prevalent. Few studies (16%) included targeted, disease-specific instruments. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Quality of Life questionnaire, the Liver Disease Quality of Life questionnaire, and the Chronic Liver Disease questionnaire are the most frequently employed targeted instruments; however, these instruments have been designed to assess QOL in patients with chronic liver disease rather than patients after liver transplantation. The present review focuses on the psychometric properties of the existing QOL instruments and discusses their individual strengths and limitations in evaluating liver transplantation recipients. The lack of a gold-standard QOL instrument for liver transplant recipients is an impediment to cross-study comparisons. We conclude that the development of a QOL instrument specifically for liver transplant recipients will improve QOL assessment in this population leading to a more nuanced understanding of the factors that influence transplant recipients' well-being.

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“…All subscales as well as the summary components are presented as scores between 0 and 100 with higher scores indicating better health status. The validity and reliability of SF-36 have been tested in patients with renal disease including those after kidney transplantation (6,7,16,18). Skalska et al validated the questionnaire in the Czech population (19).…”

Section: Procedures and Measuresmentioning

confidence: 99%

“…Despite the uncertainty in definitions, healthrelated quality of life or perceived health status is not a mere construct devoid of clinical relevance. Recent research has shown that it is a very important predictor of other outcomes in patients with chronic renal disease (5)(6).…”

mentioning

confidence: 99%

Predictors of Perceived Health Status in Patients after Kidney Transplantation

Rosenberger

Dijk

Nagyová³

et al. 2006

Transplantation

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Major differences exist in PHS among kidney transplant recipients depending on their age. Side effects of therapy are the most important predictor of PHS for all age groups. PHS of young patients mostly depends on their renal function and their social support. Education and working activities are most important for middle-aged people whereas in older patients PHS is mostly affected by comorbidity.

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Quality of life as a predictor of morbidity, mortality, and resource utilization after solid organ transplant

Cited by 13 publications

References 1 publication

Health-Related Quality of Life and Long-Term Survival and Graft Failure in Kidney Transplantation

Health-Related Quality of Life and Long-Term Survival and Graft Failure in Kidney Transplantation

A review of quality of life instruments used in liver transplantation

Predictors of Perceived Health Status in Patients after Kidney Transplantation

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