Quality of life, anxiety and depression in Sarcoidosis

Goracci, Arianna; Fagiolini, Andrea; Martinucci, M.; Calossi, Sara; Rossi, S.; Santomauro, Tonino; Mazzi, Angela; Penza, Francesco; Fossi, Antonella; Bargagli, Elena; Pieroni, Maria; Rottoli, Paola; Castrogiovanni, Paolo

doi:10.1016/j.genhosppsych.2008.04.010

Cited by 48 publications

(38 citation statements)

References 8 publications

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“…The magnitude of stressful life events was significantly higher in patients with sarcoidosis when compared with healthy controls. In a recent study of 80 patients, 44% endorsed at least one major psychiatric diagnosis using a structured interview, with major depressive disorder being the most common [47]. In this study, individuals with multisystemic involvement, asthenia, and a more severe radiographic stage, along with those receiving steroids reported a poorer quality of life [47].…”

Section: Restrictive Lung Diseasementioning

confidence: 53%

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Psychiatric aspects of chronic lung disease

Jain

Lolak²

2009

Curr Psychiatry Rep

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Chronic lung diseases continue to be common and cause significant morbidity and mortality. There is a complex interplay between psychiatric issues and pulmonary diseases. This review aims to summarize the recent literature and advances involving psychiatric aspects of lung diseases, including chronic obstructive pulmonary disease, asthma, restrictive lung disease, and cystic fibrosis. The authors include the latest findings in epidemiology, impact, etiology, screening, and management of psychiatric and pulmonary comorbidity. The relationship between mental health and lung disease, as it is between mental health and other physical illnesses, is multifactorial. Further studies continue to clarify issues and treatment guidelines for this comorbidity.

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Section: Restrictive Lung Diseasementioning

confidence: 53%

“…It is associated with a higher rate of psychiatric comorbidity, especially mood and anxiety disorders, and poorer quality of life [47]. In addition, neurosarcoidosis, which affects 5% to 10% of sarcoidosis patients, can be the source of psychiatric symptoms, including depression, dementia, and psychosis [40•].…”

Section: Restrictive Lung Diseasementioning

confidence: 99%

Psychiatric aspects of chronic lung disease

Jain

Lolak²

2009

Curr Psychiatry Rep

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“…Chang et al [27] reported depression in 60% of sarcoidosis patients, and showed correlations with female gender, economical status, access to health service and disease severity. Goracci et al [28] confirmed strong relationship between sarcoidosis and depression, and its negative impact on quality of life. De Klejn et al [29] found, that fatigue is related to depression in 34−36% and to anxiety in 43−46% of patients.…”

Section: Psychological Aspectsmentioning

confidence: 92%

Fatigue Syndrome in Sarcoidosis

Górski

Piotrowski

2016

Advances in Respiratory Medicine

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Sarcoidosis is an inflammatory disease of unknown etiology. Most commonly it results in the formation of non-caseating granulomas in intrathoracic lymph nodes and lung parenchyma, but the clinical course and picture may be complicated by extrapulmonary involvement and many non-respiratory signs and symptoms which are directly related to the disease. In addition, sarcoidosis patients may suffer from a plethora of symptoms of uncertain or unknown origin. Fatigue is one of these symptoms, and according to some authors it is reported by the majority of patients with active sarcoidosis, but also by a smaller proportion of patients with inactive sarcoidosis, or even with complete clinical and radiological remission. Therefore the term fatigue syndrome is frequently used to name this clinical problem. The definition of fatigue syndrome in sarcoidosis is imprecise and the syndrome is usually recognized by use of validated questionnaires. In this review the uptodate knowledge in this field was presented and different challenges connected with this syndrome were described.

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“…There are few reports pointing out the possible link between fatigue with depression. Goracci et al [15] reported on strong relationship between sarcoidosis and its negative impact on quality of life. De Klejn et al [16] found, that fatigue is related to depression in 34−36% and to anxiety in 43−46% of patients suffering from active sarcoidosis.…”

Section: Introductionmentioning

confidence: 99%

“…Assessment of health-related quality of life may be as important as assessment of depressive symptoms and fatigue among patients suffering from sarcoidosis [15]. Sarcoidosis Health Questionnaire (SHQ) is one of the most popular psychometric tools assessing quality of life designed for patients with sarcoidosis [18].…”

Section: Introductionmentioning

confidence: 99%

The Utility of Selected Questionnaires in the Assessment of Fatigue, Depression and Health Quality in Post-Sarcoidosis Fatigue Syndrome

Górski

Mokros

Kumor-Kisielewska

et al. 2017

Advances in Respiratory Medicine

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Introduction: The nature of post-sarcoidosis fatigue syndrome (PSFS) is unknown and tools for the assessment of health quality (HQ) in these patients have not been fully assessed. The aim was to validate the Polish version of sarcoidosis health questionnaire (SHQ) and verify the association of HQ with fatigue and depressive symptoms among Polish patients with PSFS. Material and methods: 71 patients with sarcoidosis (34 women, the mean age 47) were divided to: PSFS (n = 21), active sarcoidosis (S-A, n = 27) and sarcoidosis with complete remission (S-R, n = 23) groups. Fatigue Assessment Scale (FAS) was used to define significant fatigue (≥ 22 points). Polish version of SHQ was prepared by the authors and validated. Beck Depression Index (BDI) and Patient Health Questionnaire 9 (PHQ-9) were used to evaluate self-reported depressive symptoms. Results: Polish version of SHQ was proved reliable and valid. HQ was worse and depressive symptoms were more frequent in PSFS and S-A when compared with S-R group. SHQ total score correlated negatively with depressive symptoms (r = -0.787 for BDI and r = -0,755 for PHQ-9, p < 0.01). A negative correlation between SHQ and FAS score was found (r = -0.784, p < 0.01). FAS score correlated with depressive symptoms (r = 0.726 for BDI and r = 0.755 for PHQ-9, p < 0.01). Conclusion: Polish version of SHQ is a valuable tool for the assessment of HQ in sarcoidosis. HQ is impaired in PSFS comparing to patients with complete remission, but is comparable to active sarcoidosis. Depressive symptoms impact HQ and may influence perception of fatigue. Both fatigue and depression have a negative impact on HQ in sarcoidosis.

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Quality of life, anxiety and depression in Sarcoidosis

Cited by 48 publications

References 8 publications

Psychiatric aspects of chronic lung disease

Psychiatric aspects of chronic lung disease

Fatigue Syndrome in Sarcoidosis

The Utility of Selected Questionnaires in the Assessment of Fatigue, Depression and Health Quality in Post-Sarcoidosis Fatigue Syndrome

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