Quality of life and voice assessment in patients with early-stage glottic cancer

Arias, Fernando; Arrarás, Juan Ignacio; Asin, Gemma; Uzcanga, María; Maraví, E; Chicata, V.; Eito, C.; Zarandona, Unai Irusta; Mora, I.; Vila, M.T.; Dominguez, Miguel A.

doi:10.1002/hed.23603

Cited by 27 publications

(32 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Section: Discussionmentioning

confidence: 99%

“…From the literature, 2 studies aimed at investigating QOL in patients with early glottic cancers using the QLQ‐H&N35 . Arias et al reported that social contact was significantly better (4.6 vs 12.1; P = .009) from patients who underwent RT than those who underwent TLM. However, a similar study done by Laoufi et al reported that subscales of speech (4.51 vs 5.25; P = .04) and feeling ill (1.07 vs 1.22; P = .05) were different instead of social contact .…”

Section: Discussionmentioning

confidence: 99%

“…Arias et al reported that social contact was significantly better (4.6 vs 12.1; P = .009) from patients who underwent RT than those who underwent TLM. However, a similar study done by Laoufi et al reported that subscales of speech (4.51 vs 5.25; P = .04) and feeling ill (1.07 vs 1.22; P = .05) were different instead of social contact . One possible cause of this discrepancy may also be due to the timing of the evaluation was either not clearly defined or varied from a long range of time (range 12‐114 months) .…”

Section: Discussionmentioning

confidence: 99%

“…Because the observation time differs, controversies exist regarding voice outcomes between TLM and RT. Studies that favored RT having a superior self‐reported voice outcome lacked either information regarding the baseline condition or a diverse timing of evaluation . In a systematic review, evidence was inconclusive for RT being superior over TLM on both objective voice analysis and subjective QOL outcome .…”

Section: Introductionmentioning

confidence: 99%

“…Studies that favored RT having a superior selfreported voice outcome lacked either information regarding the baseline condition or a diverse timing of evaluation. [10][11][12] In a systematic review, evidence was inconclusive for RT being superior over TLM on both objective voice analysis and subjective QOL outcome. 13 As fluctuations of voice condition were observed in patients after TLM, the timing of voice evaluation should be well documented.…”

mentioning

confidence: 99%

See 4 more Smart Citations

Life quality improvement in hoarse patients with early glottic cancer after transoral laser microsurgery

et al. 2017

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

See 3 more Smart Citations

Life quality improvement in hoarse patients with early glottic cancer after transoral laser microsurgery

et al. 2017

View full text Add to dashboard Cite

show abstract

Quality of life and voice outcome of patients treated with transoral CO2 laser microsurgery for early glottic carcinoma (T1–T2): a 2-year follow-up study

Hendriksma

Loon

Klop

et al. 2019

Eur Arch Otorhinolaryngol

View full text Add to dashboard Cite

PurposeLongitudinal studies in laryngeal cancer can provide clinicians information about short-term and long-term functional outcomes, like quality of life (QoL) and voice outcome. This information is important when counseling patients or choosing a primary treatment modality. The present study assessed long-term (2 years) QoL and voice outcome in patients with extended T1 and limited T2 glottic carcinoma treated with transoral CO2 laser microsurgery (TLM) (unilateral type III or bilateral type II resections).MethodsThree questionnaires were administered: the Voice Handicap Index (VHI), the European Organization for Research and Treatment of Cancer (EORTC) QoL questionnaire (QLQ)-C30, the EORTC QLQ-HN35. A perceptual voice evaluation at six different time points was conducted: preoperatively, and postoperatively at 6 weeks, 3 months, 6 months, 1 year, and 2 years. Fluctuations over time were investigated.ResultsSixty-one patients were included in the analysis. Patients reported high-level functioning and low symptom scores 2 years postoperatively. Gender significantly affected the VHI scores at 2 years (mean VHI scores: female 8.7 vs. male, 23.9; p = 0.023). The major improvement in VHI scores was observed within the first 6 months. The tumor stage (T1a, T1b, and T2) significantly impacted the grade (mean scores at 2 years: 1.0, 1.9, and 1.7; p = 0.001). These scores stabilized at 6 months.ConclusionsPatients show good long-term QoL with low symptom scores, a low voice handicap, and mild to moderate dysphonia, 2 years postoperatively. Scores stabilize at 6 months and provide a clear indication of status at 1 and 2 years.

show abstract

Evolution of voice after transoral laser cordectomy for precancerous lesions and early glottic cancer

Staníková

Zeleník

Formánek

et al. 2021

Eur Arch Otorhinolaryngol

View full text Add to dashboard Cite

Purpose To evaluate voice quality evolution after a transoral laser cordectomy (TLC) for precancerous lesions and early glottic cancer. Methods This prospective study enrolled 18 patients scheduled for TLC for high-grade dysplasia, Tis, T1, and T2 glottic squamous cell cancers, from May 2017 to March 2020. Patients were grouped according to the extent of TLC: Group I (n = 11, 61.1%): unilateral subepithelial or subligamental cordectomy; Group II (n = 7, 38.9%): unilateral transmuscular, total, or extended cordectomy. Voice quality parameters, including dysphonia grade (G), roughness (R), breathiness (B), maximal phonation time (MPT), jitter, and shimmer, were evaluated before, and at 6 weeks and 6 months after the TLC. Results In Group I, the degree of G and R items remained without substantial improvement 6 weeks after surgery; however, improved above the pre-surgery level up to 6 months after surgery. The MPT, jitter, and shimmer did not change significantly at 6 weeks or 6 months post-TLC. In Group II, G, R, and B remained significantly impaired even 6 months post-surgery. Jitter, and shimmer worsened at 6 weeks, but reached preoperative levels at 6 months post-surgery. MPT was significantly worse at 6 weeks and remained deteriorated at 6 months post-surgery. All measured parameters were significantly worse in Group II than in Group I at 6 weeks and 6 months post-surgery. No patient required a phonosurgical procedure. Conclusion After a TLC, voice quality evolution depended on the extent of surgery. It did not improve at 6 weeks post-surgery. Improvements in less extent cordectomies occurred between 6 weeks and 6 months post-surgery. Understanding voice development over time is important for counseling patients when considering phonosurgical procedures.

show abstract

Quality of life and voice assessment in patients with early-stage glottic cancer

Abstract: In this cross-sectional study, voice quality, emotional functioning, and social contact were better in the RT group.

Cited by 27 publications

References 23 publications

Life quality improvement in hoarse patients with early glottic cancer after transoral laser microsurgery

Life quality improvement in hoarse patients with early glottic cancer after transoral laser microsurgery

Quality of life and voice outcome of patients treated with transoral CO2 laser microsurgery for early glottic carcinoma (T1–T2): a 2-year follow-up study

Evolution of voice after transoral laser cordectomy for precancerous lesions and early glottic cancer

Contact Info

Product

Resources

About