Quality of life and outcomes after radiofrequency His-bundle catheter ablation and permanent pacemaker implantation: Impact of treatment in paroxysmal and established atrial fibrillation

Gender differences and quality of life in atrial fibrillation: The mediating role of depression

“…It is associated with considerable morbidity and mortality [1,2,4], as well as with significant impairments in health-related quality of life (QoL) in terms of physical, social, emotional, and mental functioning [5][6][7][8]. AF patients report greater QoL impairments relative to patients with congestive heart failure or myocardial infarction (MI) [5,9].…”

Prospective Randomized Study of Ablation and Pacing Versus Medical Therapy for Paroxysmal Atrial Fibrillation

“…Of the studies to date, most have been uncontrolled, retrospective, or have not distinguished between chronic AF and PAF. [3][4][5][6][7][8][9] The only prospective study comparing medical treatment for PAF with ablation and pacing suggested superiority for the latter but did not assess the optimum pacing mode 10 ; because both VVIR 4 and DDDR/MS 3 pacing have been shown to be effective, an assessment of pacing mode is required. Similarly, no study has assessed whether the modeswitching algorithm used affects the efficacy of ablation and pacing.…”

Atrial fibrillation and quality of life after pacemaker implantation for sick sinus syndrome: Data from the Mode Selection Trial (MOST)

“…17,19 Studies in highly symptomatic patients with AF undergoing atrioventricular node ablation and often subsequent pacemaker placement also reported marked improvement in QOL in these selected patient populations. [20][21][22][23] However, in the older, less selected population enrolled in the AFFIRM QOL substudy, QOL was comparable between rate and rhythm control strategies and was also similar in SR versus AF, 24,25 suggesting that effects on QOL associated with AF were quite modest in an older, medically managed population.…”