Quality of life and needs assessment on people living with HIV and AIDS in Malawi

Fan, Angela; Kuo, Huai Ching Claire; Kao, Diana; Morisky, Donald E.; Chen, Yi Ming Arthur

doi:10.1080/09540121.2010.507742

Cited by 15 publications

(15 citation statements)

References 31 publications

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“…In Africa, the social, psychological, and medical contexts differ from those in Western countries. In Sub-Saharan African (SSA) countries hit hard by the HIV epidemic, QOL has been assessed in HIV-affected populations 9,10 . In one study from Malawi, HIV-seropositive people (267) were compared to HIV-seronegative people (598) with the use of the Short Form 36 Health Survey (SF-36) to analyse QOL 10 .…”

Section: Introductionmentioning

confidence: 99%

“…In Sub-Saharan African (SSA) countries hit hard by the HIV epidemic, QOL has been assessed in HIV-affected populations 9,10 . In one study from Malawi, HIV-seropositive people (267) were compared to HIV-seronegative people (598) with the use of the Short Form 36 Health Survey (SF-36) to analyse QOL 10 . This study concluded that HIV infection, the severity of HIV-related symptoms, and CD4 count less than 200 cells/ mm³ are associated with lower QOL.…”

Section: Introductionmentioning

confidence: 99%

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Quality of Life after First-Ever Stroke: An Interview Based Study from Blantyre, Malawi

Heikinheimo¹,

Chimbayo²

2015

Mal. Med. J

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BackgroundIn post-stroke patients, impairment of quality of life (QOL) has been associated with functional impairment, age, anxiety, depression, and fatigue. Good social support, higher education, and better socioeconomic status are associated with better QOL among stroke survivors. In Africa, studies from Nigeria and Tanzania have reported on post-stroke QOL. AimThe aim of this study was to describe QOL more than six months after first-ever stroke in Malawi. MethodsThis was an interview-based study about a stroke-surviving cohort. Adult patients were interviewed six or twelve months after their first ever stroke. HIV status, modified stroke severity scale (mNIHSS) score, and brain scan results were recorded during the acute phase of stroke. At the time of the interviews, the modified Rankin scale (mRS) was used to assess functional outcome. The interviews applied the Newcastle Stroke-specific Quality of Life Measure (NEWSQOL). All the data were analysed using Statview™: the X 2 test compared proportions, Student's t-test compared means for normally distributed data, and the Kruskal-Wallis test was used for nonparametric data. ResultsEighty-one patients were followed up at least six months after the acute stroke. Twenty-five stroke patients (ten women) were interviewed with the NEWSQOL questionnaire. Good functional outcome (lower mRS score) was positively associated with better QOL in the domains of activities of daily living (ADL)/self-care (p = 0.0024) and communication (p = 0.031). Women scored worse in the fatigue (p = 0.0081) and cognition (p = 0.048) domains. Older age was associated with worse QOL in the ADL (p = 0.0122) domain. Seven patients were HIV-seroreactive. HIV infection did not affect post-stroke QOL. ConclusionIn Malawi, within specific domains, QOL after stroke appeared to be related to patients' age, sex, and functional recovery in this small sample of patients.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Quality of Life after First-Ever Stroke: An Interview Based Study from Blantyre, Malawi

Heikinheimo¹,

Chimbayo²

2015

Mal. Med. J

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“…Accuracy of outcome data was 72%. 38 Greater reduction in mortality and better outcomes have been shown in Uganda by Mermin et al in 2008. 24 They showed that ART decreased mortality in HIV-infected individuals with CD4 count < 250 cells/mm 3 or pre-2006 WHO clinical stage 3 or 4 or recurrent herpes zoster.…”

Section: Discussionmentioning

confidence: 91%

Antiretroviral Therapy Outcomes in Malawi: Access, Mortality and Opportunistic Infections

Kachingwe

Wang

Cheng

2012

Journal of Experimental & Clinical Medicine

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“…Kabore et al (2010) found that patients in sub-Saharan Africa exposed to community-based services experienced a more rapid increase in CD4 counts and healthrelated QoL indicators. In Uganda, Kyajja et al (2010) focused on side-effects, while a Malawian study of the improvement in QoL reports that little is known about how QoL and needs/survival strategies of PLHA vary in less-developed regions (Fan, Kuo, Kao, Morisky, & Chen, 2011). In South Africa, Rosen et al (2010) found a large and sustained improvement of patients' symptom prevalence, general health, ability to perform normal activities and employment status through the first three years with ART.…”

Section: Introductionmentioning

confidence: 97%

Using an innovative mixed method methodology to investigate the appropriateness of a quantitative instrument in an African context: Antiretroviral treatment and quality of life

et al. 2013

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The relationship between quality of life (QoL) and antiretroviral treatment (ART) has mainly been studied using quantitative scales often not appropriate for use in other contexts and without taking peoples' lived experiences into consideration. Sub-Saharan Africa has the highest incidence of HIV and AIDS yet there is paucity in research done on QoL. This research report is intended to give an account of the use of a mixed method convergent parallel design as a novice approach to evaluate an instrument's context specificity, appropriateness and usefulness in another context for which it was designed. Data were collected through a qualitative exploration of the experiences of QoL of people living with HIV or AIDS (PLHA) in Africa since being on ART, as well as the quantitative measurements obtained from the HIV/AIDS-targeted quality of life (HAT-QoL) instrument. This study was conducted in three African countries. Permission and ethical approval to conduct the study were obtained. Purposive voluntary sampling was used to recruit PLHA through mediators working in community-based HIV/AIDS organisations and health clinics. Interviews were analysed through open coding and the quantitative data through descriptive statistics and the Cronbach's alpha coefficient. A much wider range and richness of experiences were expressed than measured by the HAT-QoL instrument. Although an effective instrument for use in the USA, it was found not to be sensitive, appropriate and useful in an African context in its present form. The recommendations focus on adapting the instrument using the data from the in-depth interviews or to develop a context-sensitive instrument that could measure QoL of PLHA in Africa.

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Quality of life and needs assessment on people living with HIV and AIDS in Malawi

Cited by 15 publications

References 31 publications

Quality of Life after First-Ever Stroke: An Interview Based Study from Blantyre, Malawi

Quality of Life after First-Ever Stroke: An Interview Based Study from Blantyre, Malawi

Antiretroviral Therapy Outcomes in Malawi: Access, Mortality and Opportunistic Infections

Using an innovative mixed method methodology to investigate the appropriateness of a quantitative instrument in an African context: Antiretroviral treatment and quality of life

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