Quality of Life and Late Toxicities in Head and Neck Cancer

List, Marcy A.; Stracks, John

doi:10.1007/0-306-48060-3_14

Cited by 9 publications

(8 citation statements)

References 93 publications

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“…Mucositis, and its clinical sequelae, are consistently reported as the most bothersome side effects of CRT in HNC patients and often require narcotic analgesia [17].…”

Section: Discussionmentioning

confidence: 99%

Professional oral health care reduces oral mucositis pain in patients treated by superselective intra-arterial chemotherapy concurrent with radiotherapy for oral cancer

Kubota

Kobayashi

Sakaki

et al. 2015

Support Care Cancer

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“…Mucositis, and its clinical sequelae, are consistently reported as the most bothersome side effects of CRT in HNC patients and often require narcotic analgesia [17].…”

Section: Discussionmentioning

confidence: 99%

Professional oral health care reduces oral mucositis pain in patients treated by superselective intra-arterial chemotherapy concurrent with radiotherapy for oral cancer

Kubota

Kobayashi

Sakaki

et al. 2015

Support Care Cancer

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“…Because of the location of the structures, the disease, and its treatment, this disease can cause debilitating and permanent disability. Surgery and radiotherapy can cause a visible disfigurement in facial and neckline appearance and affect vital life functions, such as the ability to swallow, taste, speak, and eat …”

Section: Introductionmentioning

confidence: 99%

“…Surgery and radiotherapy can cause a visible disfigurement in facial and neckline appearance and affect vital life functions, such as the ability to swallow, taste, speak, and eat. [3][4][5][6] The extensive rehabilitation and long-term maintenance needs of this population are complex and involve a diverse set of health care providers, including head and neck surgeons, radiation oncologists, medical oncologists, plastic and reconstructive surgeons, nurses, dentists and prosthodontists, physical rehabilitation specialists, speech and swallowing experts, nutritionists, pathologists, and adjunctive services, such as addiction services and psychiatry. [7][8][9] Collaboration between the patient and the many providers is key to restoration of swallowing, taste, and speech, and the prevention of further deterioration of physical function.…”

Section: Introductionmentioning

confidence: 99%

Survivorship care experiences, information, and support needs of patients with oral and oropharyngeal cancer

et al. 2016

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Background There is little research documenting the post-treatment experiences and needs of oral/oropharyngeal cancer survivors. Methods In this cross-sectional study, 92 patients diagnosed with oral/oropharyngeal cancer diagnosed between 2 and 5 years prior completed a survey about oral cancer information and support needs. Results About half retrospectively reported that they did not receive a written treatment summary. The desire for more oral cancer information was common: One-third or more desired more information about long-term effects, recommended follow-up, and symptoms that should prompt contacting a doctor. Support needs were less common: Only a lack of energy was rated as a significant support need. Patients who had a recurrence, did not drink alcohol, and had a greater recurrence fear desired more information. Smokers and more distressed patients reported more support needs. Conclusions Survivors reported the desire for more oral cancer information. A desire for assistance was less common.

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“…Although CRT is associated with improved efficacy, it is accompanied by an increase in toxicity, in particular mucositis, which is now almost universal 6 . Mucositis, and its clinical sequelae, are consistently reported as the most bothersome side effects of CRT in HNC patients and often require narcotic analgesia 7 . In addition, mucositis can lead to nutritional deficits requiring enteral feeding, dehydration, and treatment compromise.…”

Section: Introductionmentioning

confidence: 99%

Study of functional infrared imaging for early detection of mucositis in locally advanced head and neck cancer treated with chemoradiotherapy

et al. 2013

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Background and Purpose Chemoradiotherapy (CRT) has led to improved efficacy in treating locally advanced squamous cell carcinoma of the head and neck (LA-SCCHN) but has led to almost universal in-field mucositis. Patients treated with the same regimen often have differences in mucositis occurrence and severity. Mucositis induced via radiation is known to represent an intense inflammatory response histologically. We hypothesized that patients destined to display severe mucocutaneous toxicity would demonstrate greater alterations in thermal intensity early in therapy than identically treated counterparts. This will allow identification of patients that will require more intensive supportive care using thermal imaging technology. Materials and Methods Subjects with LA-SCCHN (oral cavity or oropharynx) being treated with the identical chemoradiotherapy regimen underwent baseline and weekly thermal imaging. Changes in skin temperature caused by mucositis and dermatitis compared with a reference area (T were calculated and correlated to grade of mucositis based on NCI-CTCAE 3.0. Results Thirty-four subjects were enrolled. Grade 3 mucositis and dermatitis was observed in 53% and 21%, respectively. We observed a statistically significant positive association between an early rise in T and mucositis grade (p value=0.03). Conclusions Thermal imaging is able to detect small and early changes in skin surface temperature that may be associated with development of mucositis in patients being treated with chemoradiotherapy.

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Quality of Life and Late Toxicities in Head and Neck Cancer

Cited by 9 publications

References 93 publications

Professional oral health care reduces oral mucositis pain in patients treated by superselective intra-arterial chemotherapy concurrent with radiotherapy for oral cancer

Professional oral health care reduces oral mucositis pain in patients treated by superselective intra-arterial chemotherapy concurrent with radiotherapy for oral cancer

Survivorship care experiences, information, and support needs of patients with oral and oropharyngeal cancer

Study of functional infrared imaging for early detection of mucositis in locally advanced head and neck cancer treated with chemoradiotherapy

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