Quality of life among postmenopausal women enrolled in the Minnesota Green Tea Trial

Webster, Allison Dostal; Finstad, Deborah; Kurzer, Mindy S.; Torkelson, Carolyn J.

doi:10.1016/j.maturitas.2017.10.013

Cited by 20 publications

(9 citation statements)

References 15 publications

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“…This questionnaire was designed by Hilditch et al (29) at the University of Toronto in Canada and contains 29 items on menopausal symptoms and complications in four dimensions, including vasomotor, psychosocial, physical, and sexual, and the total score is obtained based on a Likert scale from 1 to 6. Lower scores indicate a better quality of life, and vice versa (30). The reliability of the Persian version of this scale has been confirmed in previous studies conducted on the quality of life in Iranian women with a Cronbach's alpha of 0.8 (9).…”

Section: The Menopause-specific Quality Of Life (Menqol) Questionnairesupporting

confidence: 68%

The Effect of Mindfulness-Based Cognitive Therapy on Quality of life in Perimenopausal Women

Enjezab

Zarehosseinabadi

Farzinrad

et al. 2019

Iran J Psychiatry Behav Sci

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Background: Menopause is a physiological alteration affecting women's quality of life. Mindfulness-based cognitive therapy (MBCT) as a psychological and non-pharmacological method can be effective to improve the quality of life in perimenopausal women. Objectives: The present study was conducted to determine the effectiveness of MBCT on the quality of life in perimenopausal women. Methods: This randomized controlled trial was conducted on 73 perimenopausal women from August 2017 to February 2018 in four health centers in Yazd. They were randomly divided into the intervention (n = 36) and control (n = 37) groups by using simple random sampling method; indeed, the random number table. The MBCT was given once a week to the intervention group over eight two-hour sessions and the control group received no intervention. The data collection instruments included a demographic questionnaire, Cooperman's index, and the menopause-related quality of life questionnaire, which were fulfilled by both groups before, immediately after, and one month after the completion of the intervention. Results: In the intervention group, the mean score of quality of life and its dimensions (except for the sexual dimension) immediately and one month after the completion of the intervention showed a significant reduction compared with the control group (P < 0.001). Also, the improvement of the quality of life and its dimensions mean scores was significant in three intervals of the study in the intervention group (P < 0.001). Conclusions: Given the effectiveness of MBCT in enhancing the quality of life in perimenopausal women, this method is recommended to be used as a supportive method for management of perimenopausal period.

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Section: The Menopause-specific Quality Of Life (Menqol) Questionnairesupporting

confidence: 68%

The Effect of Mindfulness-Based Cognitive Therapy on Quality of life in Perimenopausal Women

Enjezab

Zarehosseinabadi

Farzinrad

et al. 2019

Iran J Psychiatry Behav Sci

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“…To enhance the overall quality of life of women during transition to menopause and during post-menopausal period, it is important for the woman to know necessary information on what menopause is and how to deal with its related problems. Clinicians are recommended to interact with middle-aged women in order to give them advice on how to manage this crucial period of their lives [ 23 ]. This study aimed to evaluate the knowledge, attitudes and practices towards menopause among middle-aged Congolese women.…”

Section: Discussionmentioning

confidence: 99%

Knowledge, attitudes and practices towards menopause among Congolese middle-aged and postmenopausal women

Muchanga¹,

Lumumba²,

Kamba³

et al. 2021

Pan Afr Med J

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Introduction with the increase in life expectancy, women will live longer during their postmenopausal period. To improve their quality of life, they should be aware of what challenges they will be facing. This study aimed to evaluate the knowledge, attitudes and practices of middle-aged women towards menopause. Methods in this cross-sectional study, data collected using a multistage clustered random sampling from 54 health centres in the Democratic Republic of Congo were used. Participants filled a questionnaire derived from the menopause rating scale and from local beliefs. The knowledge, attitudes and practices towards menopause were evaluated among pre- and postmenopausal women. Results of the 353 women, both pre- and postmenopausal women knew the definition of menopause but for the symptoms, postmenopausal women were more informed than premenopausal. For the attitudes and practices towards menopause, while both had equally positive attitudes, the premenopausal women did not know which practice to adopt. Conclusion Congolese women had limited knowledge, positive attitudes and unconventional practices towards menopause. Health-care providers, therefore, need to dispense appropriate advice to middle-aged women before the advent of menopause.

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“…In general, menopausal women have been considered to suffer from cognitive disorders as a result of estrogen decline. However, this viewpoint was challenged by a recent study that demonstrated that women aged 50-54.9 years had even poorer memory than older women (39). Their verbal memory did decline at the menopausal transition but probably rebounded during the postmenopausal stage (40).…”

Section: Discussionmentioning

confidence: 99%

Effects of estrogen deprivation on memory and expression of related proteins in ovariectomized mice

et al. 2020

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Background: The ovariectomized (OVX) rodent model is most widely used for studying the influence of estrogen deprivation on memory. However, the results of these studies are inconsistent, in that the memory of OVX rodents shows either impairment or no change. These inconsistent outcomes increase the difficulty of researching neurochemical mechanisms and evaluating drug efficacy. One possible explanation for these discrepancies might be that the time point for memory examination after OVX varies considerably among studies. The aim of our study was to investigate the effects of estrogen deprivation on memory and the expression of memory-related proteins at different times after OVX.Methods: Novel object recognition (NOR), step-through passive avoidance (STPA) and the Morris water maze (MWM) were performed to evaluate the memory performance of mice at different times after OVX.The expressions of BDNF, TrkB, ULK1 and LC3II/LC3I in the hippocampus were also assessed to explore the relevant mechanisms.Results: After OVX, a significant memory impairment was found in the STPA test at 4 weeks. In the NOR and MWM tests, however, memory deficits were not observed until 8 weeks post-OVX. Interestingly, at 8 weeks, a memory rebound was found in the STPA test. In the hippocampus, the levels of BDNF and TrkB in OVX mice were markedly decreased at 4 and 8 weeks. Subsequently, a significant decrease in the ULK1 and LC3II/LC3I level in OVX mice was observed at 8 weeks.Conclusions: Memory impairment in mice was observed as early as 4 weeks after OVX, although there was a possibility of memory rebound with the prolongation of estrogen deprivation. Eight weeks of estrogen deprivation would be more likely to induce hippocampus-dependent memory impairment. This progressive impairment of memory might be due to the downregulation of the BDNF/TrkB signaling pathway at the early post-OVX stage, while the decrease of autophagy level in the later stage might also contribute to these progressive alterations. The underlying relationship between the BDNF/TrkB signaling pathway and autophagy in this progressive impairment of memory requires further study.

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Quality of life among postmenopausal women enrolled in the Minnesota Green Tea Trial

Abstract: The findings of this descriptive analysis of postmenopausal women may help clinicians counsel women about expectations and treatment options to address menopause-associated symptoms and the relationship between postmenopausal symptoms and overall health.

Cited by 20 publications

References 15 publications

The Effect of Mindfulness-Based Cognitive Therapy on Quality of life in Perimenopausal Women

The Effect of Mindfulness-Based Cognitive Therapy on Quality of life in Perimenopausal Women

Knowledge, attitudes and practices towards menopause among Congolese middle-aged and postmenopausal women

Effects of estrogen deprivation on memory and expression of related proteins in ovariectomized mice

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