Quality of life among advanced cancer patients in Vietnam: a multicenter cross-sectional study

Huyen, Bui Thanh; Anh, Pham Thi Van; Dai, Duong Le; Guo, Ping; Thuc, Pham Van; Khue, Luong Ngoc; Krakauer, Eric L.; Harding, Richard

doi:10.1007/s00520-021-06012-3

Cited by 8 publications

(5 citation statements)

References 18 publications

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“…lowest, but still adequate, Cronbach's α was Social Relationships. This finding is consistent with the results of the initial standardization of the instrument in the Greek language (Ginieri-Coccossis et al, 2012), and with other studies, in which the Cronbach's α for this domain was even lower (de Mol et al, 2018;Lin et al, 2019;Huyen et al, 2021). One possible explanation is the small number of items in the Social Relationships domain.…”

Section: Discussionsupporting

confidence: 91%

“…The psychometric properties of this instrument have been evaluated in patients with a variety of types of cancer and at different phases of the disease progression (Van Esch et al, 2011;Lin et al, 2017), but to the best of our knowledge, there is little documentation of its psychometric properties in patients with advanced cancer. A recent study testing the psychometric characteristics of the WHOQOL-BREF in patients with advanced cancer in Vietnam recorded excellent internal consistency, reliability, and discriminant validity (Huyen et al, 2021), and satisfactory psychometric properties of this instrument were also demonstrated in a sample of patients with advanced stage lung cancer (de Mol et al, 2018).…”

Section: Introductionmentioning

confidence: 92%

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The WHOQOL-BREF instrument: Psychometric evaluation of the Greek version in patients with advanced cancer and pain and associations with psychological distress

et al. 2022

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Objectives Assessment of the psychometric characteristics of the Greek version of the brief World Health Organization Quality of Life Instrument (WHOQOL-BREF) in patients with advanced cancer and pain, and exploration of the association between psychological distress and quality of life (QoL). Method The sample consisted of 145 patients with advanced cancer and pain who completed the WHOQOL-BREF, the Symptom Checklist-90 (SCL-90), and the Pain Visual Analogue Scale (VAS). In analysis, the following methods were used: Cronbach's alpha, Item Response Theory (IRT), polychoric, Pearson and polyserial correlation, t-test, and Linear regression. Results The internal consistency was high for all domains of the WHOQOL-BREF (Cronbach's α ≥ 0.731). Similarly, with the exception of three items, the WHOQOL-BREF items has large discrimination parameters suggesting that they have a high ability in differentiating subjects. On SCL-90, the three dimensions with the highest scores were Depression, Somatization, and Anxiety. The overall score for psychological distress, the Global Severity Index (GSI), showed significant negative association with all the WHOQOL-BREF factor scores (Physical Health: B = −1.488, p < 0.001, Psychological Health: B = −1.688, p < 0.001, Social Relationships: B = −0.910, p < 0.001, Environment: B = −1.064, p < 0.001). Male gender was associated with lower scores for Social Relationships (B = −0.358, p = 0.007) and Environment (B = −0.293, p = 0.026). Significance of results The Greek version of the WHOQOL-BREF showed good psychometric properties in patients with advanced cancer and can be used as a reliable instrument in clinical practice. The level of psychological distress can be considered a determinant of QoL in patients with advanced cancer and pain, independently of pain intensity or other clinical characteristics. In cancer, the disease process can activate multiple physiological and psychological mechanisms that lead to a wide range of symptoms of psychological distress. To improve their QoL, psychological intervention focused on the identification and alleviation of psychological distress in patients with advanced cancer, and help in finding meaning in their experience, should be provided.

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Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 92%

The WHOQOL-BREF instrument: Psychometric evaluation of the Greek version in patients with advanced cancer and pain and associations with psychological distress

et al. 2022

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“…In the present study, the ECOG score ranked first in the nomogram. Other studies also demonstrated the association between ECOG score and HRQoL among advanced cancer patients (37,38). In the present study, targeted therapy was found to be a positive contributor to improving HRQoL among lung cancer patients.…”

Section: B Asupporting

confidence: 76%

“…In our nomogram, we also included four model predictors, because a higher ECOG score, no targeted therapy, a higher anxiety score, and a larger number of comorbidities were associated with poorer HRQoL. Previous studies had already demonstrated that ECOG scores were closely relevant to HRQoL (35)(36)(37)(38). For example, Daly et al (35) showed that an ECOG score of 3 or 4 was independently related to poorer HRQoL among incurable cancer patients, and the odd ratio could be up to 14.33, indicating the importance of the variable.…”

Section: B Amentioning

confidence: 99%

Prediction of postoperative health-related quality of life among patients with metastatic spinal cord compression secondary to lung cancer

Fu,

Shi,

Zhao

et al. 2023

Front. Endocrinol.

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BackgroundHealth-related quality of life (HRQoL) is a critical aspect of overall well-being for patients with lung cancer, particularly those with metastatic spinal cord compression (MSCC). However, there is currently a lack of universal evaluation of HRQoL in this specific patient population. The aim of this study was to develop a nomogram that can accurately predict HRQoL outcomes in patients with lung cancer-related MSCC.MethodsA total of 119 patients diagnosed with MSCC secondary to lung cancer were prospectively collected for analysis in the study. The least absolute shrinkage and selection operator (LASSO) regression analysis, along with 10-fold cross-validation, was employed to select the most significant variables for inclusion in the nomogram. Discriminative and calibration abilities were assessed using the concordance index (C-index), discrimination slope, calibration plots, and goodness-of-fit tests. Net reclassification index (NRI) and integrated discrimination improvement (IDI) analyses were conducted to compare the nomogram’s performance with and without the consideration of comorbidities.ResultsFour variables were selected to construct the final nomogram, including the Eastern Cooperative Oncology Group (ECOG) score, targeted therapy, anxiety scale, and number of comorbidities. The C-index was 0.87, with a discrimination slope of 0.47, indicating a favorable discriminative ability. Calibration plots and goodness-of-fit tests revealed a high level of consistency between the predicted and observed probabilities of poor HRQoL. The NRI (0.404, 95% CI: 0.074–0.734, p = 0.016) and the IDI (0.035, 95% CI: 0.004–0.066, p = 0.027) confirmed the superior performance of the nomogram with the consideration of comorbidities.ConclusionsThis study develops a prediction nomogram that can assist clinicians in evaluating postoperative HRQoL in patients with lung cancer-related MSCC. This nomogram provides a valuable tool for risk stratification and personalized treatment planning in this specific patient population.

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“…By gauging cancer patients’ satisfaction with their care journey, health care providers can identify areas for improvement, leading to better patients’ experiences and potentially even improved health outcomes. Previous studies among Vietnamese cancer patients primarily focused on health-related quality of life in both newly admitted and established cancer patients [ 10 , 11 ], with specific diagnoses such as gastric cancer [ 12 ] and breast cancer [ 13 ]. The healthcare facilities in Vietnam are divided into four levels, corresponding to a hierarchical administrative organization: communal, district, provincial, and national/central.…”

Section: Introductionmentioning

confidence: 99%

Adult cancer patients’ barriers to and satisfaction with care at a National Cancer Hospital in Vietnam

Vu,

Weiss,

Nguyen

et al. 2024

PLoS ONE

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Study objective This study assessed the overall satisfaction with oncological care, including barriers to care, and identified its associated predictors among adult cancer patients in Vietnam. Methods In this cross-sectional study, we enrolled 300 adult cancer patients receiving inpatient care at a large urban oncological hospital between June and July 2022. Multivariable linear regression analyses examined associations between patient experiences and overall satisfaction ratings with cancer care. Results The mean overall satisfaction with oncological care was 8.82 out of 10, with 98.0% recommending this facility to their friends and family. In an adjusted model, being female (β = 0.29, 95%CI: 0.04, 0.53), endorsing satisfaction with patient-nurse communication (β = 0.33, 95%CI: 0.13, 0.53), patient-doctor communication (β = 0.40, 95%CI: 0.11, 0.70), and psychoeducation about oncological medication management (β = 0.30, 95%CI: 0.14, 0.45) were positively associated with overall ratings. In contrast, individuals with delays in treatment scheduling reported lower overall satisfaction with oncological care (β = -0.38, 95%CI: -0.64, -0.13). Patients perceived health system, social/environmental, and individual barriers to care: worries about income loss due to attending treatment (43.3%); fear, depression, anxiety, and distress (36.8%); concerns about affordability of treatment (36.7%) and transportation problems (36.7%); and excessive waiting times for appointments (28.8%). Conclusion This study showed high overall patient satisfaction with cancer care quality. Patient-centered communication strategies and psychoeducation about oncological medication management may be targeted to further enhance the cancer inpatient experience. Raising awareness about treatment options and services, and integrating mental health awareness into oncological care may ameliorate patient distress and facilitate greater satisfaction with oncological treatment processes.

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Quality of life among advanced cancer patients in Vietnam: a multicenter cross-sectional study

Cited by 8 publications

References 18 publications

The WHOQOL-BREF instrument: Psychometric evaluation of the Greek version in patients with advanced cancer and pain and associations with psychological distress

The WHOQOL-BREF instrument: Psychometric evaluation of the Greek version in patients with advanced cancer and pain and associations with psychological distress

Prediction of postoperative health-related quality of life among patients with metastatic spinal cord compression secondary to lung cancer

Adult cancer patients’ barriers to and satisfaction with care at a National Cancer Hospital in Vietnam

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