Quality of life after endoscopic procedures for chronic pancreatitis: A multicentre study

Abstract

BackgroundChronic Pancreatitis (CP) causes morphological changes in the pancreatic tissue, leading to complications and pain, which may require endoscopic interventions.ObjectiveOur aim was to determine the frequency of endoscopic procedures (EP) in CP patients and to analyse pain and quality of life (QoL) in these patients after their EP.MethodsThis study included 1327 CP patients from the Scandinavian Baltic Pancreatic Club (SBPC) database including four countries and eight centres. We analysed patients undergoing EPs and gathered information on the EP, pancreatic function, pain, disease and duration. The EORTC C‐30 QoL questionnaire was gathered prospectively and multivariable analysis was conducted on independent parameters between the groups. The reference population had no interventions (n = 870).Results260 CP patients (22%) underwent EPs, median one year (range 0–39 years) after CP diagnosis. 68% were males. The median age was 59 (20–90) years. Most common aetiological factors were alcohol in 65% and smoking in 71%. Extracorporeal shock wave lithotripsy (ESWL) was used in 6% of the CP population and in 21% of the EP group. Biliary duct stenting was performed on 37% and pancreatic stenting was performed on 56% of the patients. There was no difference in pain patterns between patients who had pancreatic stenting and the reference population. The EP group had slightly better QoL (p = 0.047), functioning and fewer symptoms than the reference population, in the multivariable analysis there was no interaction effect analysis between the groups. The pancreatic stent group had better QoL and the same amount of pain than the reference group. The patients who needed later surgery (23%) had more pain (p = 0.043) and fatigue (p = 0.021).ConclusionsOne in five of the CP patients underwent EP. These patients scored higher on QoL responses and had better symptom scores. CP patients who had pancreatic stenting performed had the same pain patterns as the reference population. Randomised prospective trials are needed to determine the effect of endoscopy procedures on CP patients.

Assessing the Impact of Medication and Stenting on the Quality of Life of Patients With Chronic Pancreatitis: A Prospective Study

“…Stenting, when indicated, significantly improves the global health score and role functioning. These findings were in line with the study conducted by Parhiala et al [24].…”

Comments on quality of life after endoscopic procedures for chronic pancreatitis: A multicentre study

“…2 The number of smokers in the reference population was found to be significantly higher when compared with the EP group. 1 Secondly, the EP itself may contribute In conclusion, while this study holds value and significance in guiding clinical practice, further refinement of the study design is necessary to enhance the reliability of the results.…”

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We recently read with interest the studies related to quality of life (QoL) after endoscopic procedures (EP) for chronic pancreatitis (CP). 1 The authors discovered that the group of patients who underwent EP experienced a higher QoL in comparison to those who did not require any intervention. They speculated that this improvement could be This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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“…We recently read with interest the studies related to quality of life (QoL) after endoscopic procedures (EP) for chronic pancreatitis (CP). 1 The authors discovered that the group of patients who underwent EP experienced a higher QoL in comparison to those who did not require any intervention. They speculated that this improvement could be attributed to the alleviation of pain and symptoms resulting from the EP.…”

“… 2 The number of smokers in the reference population was found to be significantly higher when compared with the EP group. 1 Secondly, the EP itself may contribute to the improvement of QoL in patients with CP. A national cohort study conducted in the Netherlands demonstrated that patients diagnosed with CP who underwent invasive interventions, such as endoscopy, experienced gradual enhancements in both physical and mental dimensions of their QoL.…”