Quality of life after definitive treatment for bladder cancer: A systematic review and meta-analysis

Francolini, Giulio; Ghoshal, Arunangshu; Caini, Saverio; Piazzini, Tessa; Becherini, Carlotta; Detti, Beatrice; Di Cataldo, Vanessa; Valzano, Marianna; Visani, Luca; Salvestrini, Viola; Olmetto, Emanuela; Desideri, Isacco; Meattini, Icro; Livi, Lorenzo

doi:10.1016/j.radonc.2023.110038

Cited by 3 publications

(1 citation statement)

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“…A recent study by Francolini et al [ 32 ] focused on evaluating the impact of radical cystectomy (RC), continent cutaneous urinary diversion (CCUD), orthotopic neobladder (ONB), and trimodal therapy (TMT) on the quality of life (QoL) of patients with non-metastatic muscle-invasive bladder cancer (MIBC). The findings highlighted a significant advantage of ONB over other methods in terms of Physical Functioning, with a pooled mean standardized difference of −0.73 SD, and Emotional Functioning, with a −0.16 SD difference.…”

Section: Discussionmentioning

confidence: 99%

The Assessment of SF-36 Survey for Quality-of-Life Measurement after Radical Cystectomy for Muscle-Invasive Bladder Cancer: A Systematic Review

Barbos,

Feciche,

Latcu

et al. 2024

Diseases

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This study presents a systematic review of the literature on individuals’ health-related quality of life (HRQoL) following radical cystectomy for muscle-invasive bladder cancer (MIBC), utilizing the Short Form-36 Health Survey (SF-36) as a primary assessment tool. The review was designed as an exhaustive literature search across three major databases including PubMed, Scopus, and Embase up to December 2023, using the PRISMA guidelines. The selection process refined 2281 identified articles down to 11 studies meeting our inclusion criteria. These studies encompassed a diverse demographic and clinical profile of 774 participants, with follow-up durations ranging from 3 to 130 months, thereby offering insights into both short-term and long-term HRQoL outcomes. The results highlighted significant alterations in individuals’ HRQoL across various domains post-radical cystectomy. Notably, the Physical Functioning (PF) and Bodily Pain (BP) domains generally scored higher, indicating a moderate to high perceived physical health status. However, the Role Physical (RP) and Role Emotional (RE) domains showed variability, reflecting the challenges in daily role fulfillment and emotional adjustment post-surgery. A marked variability in physical recovery was observed, with studies reporting significant differences in PF and RP scores between patient groups. The General Health (GH) and Vitality (VT) domains sometimes reflected perceived deteriorations, whereas the Mental Health (MH) scores suggested that many patients maintained or achieved high levels of well-being post-operatively. The conclusions drawn from this systematic review underscore the profound and multi-faceted impact of radical cystectomy on HRQoL, varying widely between studies, being influenced by geographic factors, surgical methods, and the time of evaluation. The findings emphasize the necessity for holistic patient care approaches that address both physical and emotional rehabilitation, aiming to improve HRQoL outcomes.

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Section: Discussionmentioning

confidence: 99%